Nutrient Regulation during Pregnancy, Lactation, and Infant Growth / Edition 1

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Describes changes in the metabolism of important nutrients during pregnancy and lactation, including the physiological basis for the changes and their implications for nutrient requirements and assessment. Considers such issues as inter-relationships between endocrine changes and nutrient metabolism at the tissue, cellular, and molecular level; alterations in nutrient binding proteins; the efficiency of nutrient absorption and retention; and the impact on maternal as well as fetal nutritional status. The 25 papers are from an August 1992 conference in Helsinki, Finland. Annotation c. Book News, Inc., Portland, OR (
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Table of Contents

1 Mechanisms of Fetal Growth Retardation in the Underweight Mother 1
2 Energy Balance in Pregnancy and Lactation 11
3 Influence of Body Composition on Food Intake 27
4 Cellular Mechanisms for the Regulation of Adipose Tissue Lipid Metabolism in Pregnancy and Lactation 45
5 Animal Models for the Study of Adipose Regulation in Pregnancy and Lactation 71
6 Endocrine Regulation of Nutrient Flux in the Lactating Woman: Do the Mechanisms Differ from Pregnancy? 85
7 Maternal Fatness in Mexican Women Predicts Body Composition Changes in Pregnancy and Lactation 99
8 Maternal Anthropometry Predicts Benefit in Lactational Performance of Undernourished Guatemalan Women 109
9 The Physiological Significance of Circulating Transferrin Receptors 119
10 The Consequences of Iron Deficiency and Anemia in Pregnancy 127
11 Folate Binding Proteins: Mechanisms for Placental and Intestinal Uptake 141
12 Iron and Folate Supplementation during Pregnancy: Maternal and Fetal Consequences 151
13 Folate Status during Pregnancy and Lactation 157
14 Vitamin B[subscript 12] Metabolism and Status during Pregnancy, Lactation and Infancy 173
15 The Function of Vitamin A in Cellular Growth and Differentiation, and Its Roles during Pregnancy and Lactation 187
16 The Role of Vitamin A in Child Growth, Development and Survival 201
17 Molecular Basis for Abnormal Parturition in Zinc Deficiency in Rats 209
18 Zinc Supplementation and Child Growth in Ecuador 215
19 Whole Body Zinc Metabolism in Full-Term Breastfed and Formula Fed Infants 223
20 Cellular Growth and Differentiation during Embryogenesis and Fetal Development: The Role of Vitamin D 227
21 Effect of Calcium Deficiency on Vitamin D Metabolism 237
22 Calcium Intakes and Bone Densities of Lactating Women and Breast-Fed Infants in The Gambia 243
23 Interactions between Zinc, Vitamins A and D, and Hormones in the Regulation of Growth 257
24 Stable Isotopes for Measurement of Nutrient Dynamics during Pregnancy and Lactation 265
25 Issues in Constant Tracer Infusion and Mineral Metabolism 279
Index 291
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