Nutrients in Cancer Prevention and Treatment / Edition 1

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Overview

In Nutrients in Cancer Prevention and Treatment, leading researchers present the most up-to-date findings available on the role of vitamins and diet in both cancer prevention and treatment. Their articles offer new insights into how vitamins act in our bodies and the effects of vitamins on gene regulation.

Highlights include preliminary data showing that high doses of certain vitamins in combination with conventional therapeutic agents may enhance their growth inhibitory effects on tumor cells, and that some vitamins inhibit protein kinase C activity, increase the production of certain growth factors, and modulate the expression of key oncogenes. Several articles illuminate the role of protease inhibitors, calories, exercise, and fat in carcinogenesis.

Nutrients in Cancer Prevention and Treatment is an excellent reference source for those involved in nutrition and cancer research, as well as for those oncologists who are treating and caring for cancer patients. It should stimulate much new research on all the many promising areas of basic and clinical nutritional oncology.

The book contains black-and-white illustrations.

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Editorial Reviews

Booknews
Leading researchers present the latest findings on the role of vitamins and diet in both cancer prevention and treatment, offering new insights into how vitamins act in the body and the effects of vitamins on gene regulation. Highlights include preliminary data showing that high doses of certain vitamins in combination with conventional therapeutic agents may enhance their growth inhibitory effects on tumor cells, and that some vitamins inhibit protein kinase C activity, increase the production of certain growth factors, and modulate the expression of key oncogenes. Several articles illuminate the role of protease inhibitors, calories, exercise, and fat in carcinogenesis. For researchers and oncologists. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780896033184
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 10/2/2007
  • Series: Experimental Biology and Medicine Series , #27
  • Edition description: 1995
  • Edition number: 1
  • Pages: 395
  • Product dimensions: 9.00 (w) x 6.00 (h) x 1.06 (d)

Table of Contents

Part I. Carcinogenesis. G Protein Pathways and Regulation of Neoplastic Transformation. Part II. Cancer Prevention Studies: Lab Studies. Vitamin E Succinate Inhibits Protein Kinase C: Correlation with Its Unique Inhibitory Effects on Cell Growth and Transformation. Vitamin E Succinate: Mechanisms of Action as Tumor Cell Growth Inhibitor. Vitamin D, Gene Expression, and Cancer. Mechanisms of Cancer Prevention: Effects of Protease Inhibitors on Proteases and Gene Expression. Antioxidants and Cancer Prevention In Vivo and In Vitro. Ascorbic Acid and Gastrointestinal Cancer. Biochemistry and Pharmacology of Retinoids in Relation to Chemoprevention of Cancer. Involvement of Retinoic Acid Nuclear Receptors in Transcriptional Regulation of Tissue Transglutaminase, the Gene Involved in Apoptosis. Mechanisms of Dietary Fat-Induced Colon Cancer Promotion. Calories and Exercise as Modifiers of Cancer Risk. Polcyclic Aromatic Hydrocarbon-DNA Adducts in Smokers and Their Relationship to Micronutrient Levels and Glutathione-S-Transferase M1 Genotype. Aspects of Commercial Deep-Fat Frying of Fallafel and Its Relation to Liver Tumor. Part III. Cancer Prevention Studies: Human Studies. Antioxidant Vitamins and Cancer: The Physicians' Health Study and Women's Health Study. Beta-Carotene and Antioxidant Nutrients in Oral Cancer Prevention. Nutritional Prevention Trials for Colorectal Neoplasia. Part IV. Cancer Treatment Studies: Lab Studies. Vitamins Induce Cell Differentiation, Growth Inhibition, and Enhance the Effect of Tumor Therapeutic Agents on Some Cancer Cells In Vitro. Molecular and Biochemical Control of Tumor Growth Following Treatment with Carotenoids or Tocopherols. Inhibition and Regression of Experimental Oral Cancer by Beta Carotene and Vitamin E: Emerging Concepts. Novel Approaches to the Prevention of Chemotherapy-Induced Alopecia. Part V. Cancer Treatment Studies: Human Studies. Role of Vitamin A and Its Derivatives in the Treatment of Human Cancer. Use of Vitaminsas Adjunct to Conventional Cancer Therapy. Orthomolecular Treatment of Cancer. Index.

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