Nutritional Oncology / Edition 1

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Nutritional Oncology is an emerging field with great significance for the prevention and treatment of cancer. Over the last decade, the number of medical oncologists, nurses, dietitians, and basic scientists concerned with this field has increased markedly. Molecular biology and genetics remain central to this interdisciplinary field which integrates basic science and its clinical application. Cancer results from the expression of genomic changes. Nutritional oncology seeks to modify the environmental factors influencing these genetic changes and their expression at every stage of carcinogenesis, from initiation of the cancer cell to its metastatic spread to other areas of the body.In this regard, nutritional oncology is relevant to some of the most common forms of cancer including, breast, prostate, colon, ovarian, uterine, and pancreatic cancers.

Nutritional Oncology defines this rapidly emerging area of tremendous interest to researchers, a field poised to become a subfield of oncology. This reference provides an assessment of nutritional impact on the development and growth of cancer (or the prevention of such development and growth) as well as its role in cancer treatment. In addition to an overall discussion of nutrition and cancer, the book discusses specific nutrients and classes of nutrients. It also covers various clinical trials in nutritional care.

Audience: Research and graduate students in both nutrition and oncology; researchers investigating the intersection of these areas and the impact of nutrition both in prevention and therapeutics.

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Editorial Reviews

From The Critics
...this volume provides a synthesis of decades of research into the relations between cancer and nutrition. It provides the foundation for a new paradigm in oncology and should be studied by everyone involved in the prevention or treatment of cancer.
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Product Details

  • ISBN-13: 9780123359605
  • Publisher: Elsevier Science & Technology Books
  • Publication date: 11/20/1998
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 632
  • Product dimensions: 8.77 (w) x 11.26 (h) x 1.32 (d)

Meet the Author

Professor of Medicine, David Geffen School of Medicine at UCLA; Associate Director, UCLA-NIH Clinical Nutrition Research Unit
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Table of Contents

Introduction: The Principles of Nutritional Oncology
Sect. I Biological Principles of Nutritional Oncology
1 Fundamentals of Nutrition: Applications to Cancer Research
2 The Cancer-Related Genes: Oncogenes, Tumor Suppressor Genes, and the DNA Damage-Responsive Genes
3 Invasion and Metastasis
4 Assessing Effects of Nutrition on Immune Function
5 Immunobiology of Melanoma: Relevance to Nutritional Oncology
Sect. II Nutrition and the Etiology of Cancer
6 The Epidemiologic Basis for Nutritional Influences on the Cancer Cell
7 Molecular Epidemiology and the Genetic Susceptibility to Cancer
8 Nutritional Modulation of the Carcinogenesis Process
9 Nutritional Epidemiology
10 Principles of Experimental Nutrition in Cancer Research
11 Dietary Assessment Tools: Nutritional Assessment of the Cancer Patient
12 Energy Balance, Anthropometry, and Cancer
13 Fruit and Vegetable Intake and Cancer
14 Dietary Fiber, Carbohydrates, and Cancer
15 Dietary Lipid Modulation of Immune Response in Tumorigenesis
16 Selenium and Cancer
17 Vitamin D and Calcium in Colorectal and Prostate Cancers
18 Oxidant Stress and Host Oxidant Defense Mechanisms
19 Alcohol and Cancer
20 Nutrition and Tobacco-Related Cancer
Sect. III Diet, Nutrition, and Cancer Prevention
21 The Challenge of Cancer Prevention and Control: Diet, Nutrition, and Cancer Prevention
22 Cancer Chemoprevention: Subject Cohorts with Early Neoplasia, Agents, and Intermediate Marker Endpoints in Clinical Trials Evaluated by Computer-Assisted Image Analysis
23 Dietary Guidelines, Dietary Assessment, and Cancer Prevention
24 Dietary Supplements, Medical Foods, and Functional Foods
25 Targeting the Action of Isoprenoids and Related Phytochemicals to Tumors
26 Garlic and Other Allium Vegetables in Cancer Prevention
27 Diet and Skin Cancer
28 Nutrition and Chemoprevention of Head, Neck, and Lung Cancers
29 Breast Cancer
30 Prostate Cancer
31 Nutrition and Bladder Cancer
32 Gastric Cancer
33 Nutrient-Gene Interactions and Prevention of Colorectal, Liver, and Pancreatic Cancer
34 Leukemia and Lymphoma
Sect. IV Nutritional Assessment and Therapy of the Cancer Patient
35 Principles of Cancer Therapy
36 Nutritional and Biochemical Aspects of the Cancer Patient
37 Cancer Cachexia and Anorexia
38 Body Cell Mass and Survival in the AIDS Patient
39 Wasting, Micronutrient Status, and Nutritional Chemoprevention in HIV/AIDS and Cancer
40 Assessing Endocrine Effects of Cancer and Ectopic Hormone Syndromes
41 Total Parenteral Nutrition in Cancer Patients
42 Enteral Nutrition in Cancer Patients
43 Nutritional Support and Quality of Life
Sect. V Clinical Trials in Nutritional Oncology
44 The Multicenter Trial and the Cooperative Group in Nutritional Oncology Research
45 Modern Statistical Regression Methods for a Longitudinal Dietary Intervention Feasibility Study
46 Future Directions in Cancer and Nutrition Research: Gene-Nutrient Interaction and the Xenobiotic Hypothesis
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