Obesity and Overeating: Research Fundamentals

Obesity and Overeating: Research Fundamentals

by Wiley
Obesity and Overeating: Research Fundamentals

Obesity and Overeating: Research Fundamentals

by Wiley

eBook

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Overview

With the increasing worldwide incidence of obesity and the resulting increase in metabolic disorders such as diabetes, cardiovascular diseases and some cancers, an understanding of the multitude of factors that contribute to obesity is crucial for researchers to develop more effective treatments. This collection of overviews and protocols provides the reader with an introduction to the major features of obesity research, including the interplay between energy balance, hormones and neurobiological networks. An overview is provided which describes the animal models of obesity most commonly utilized in research. A standardized laboratory protocol for producing diet-induced obesity (DIO) in both mouse and rat is provided as are protocols that describe how diet formulation can be modified to generate mouse models of human metabolic pathologies. Protocols are also provided for testing the effects of dietary manipulations, caloric restriction and potential therapeutics.

This e-book — a curated collection from eLS, WIREs, and Current Protocols — offers a fantastic introduction to the field of obesity research for students or interdisciplinary collaborators.


Product Details

ISBN-13: 9781118734292
Publisher: Wiley
Publication date: 07/12/2013
Series: Life Science Research Fundamentals
Sold by: JOHN WILEY & SONS
Format: eBook
Pages: 140
File size: 3 MB

About the Author

Wiley empowers learners, researchers, universities, and corporations to achieve their goals in an ever-changing world. For over 200 years, Wiley has been helping people and organizations develop the skills and knowledge they need to succeed. Wiley develops digital education, learning, assessment, and certification solutions to help universities, businesses, and individuals move between education and employment and achieve their ambitions. By partnering with learned societies, we support researchers to communicate discoveries that make a difference. Our online scientific, technical, medical, and scholarly journals, books, and other digital content build on a 200-year heritage of quality publishing.

Table of Contents

Introduction

Energy Balance, Obesity and Type 2 Diabetes
eLS
M. Daniel Lane

Neurobiology of Overeating
eLS
Eric Stice and Kyle S. Burger

Primary Hormones and Receptors Studied in Obesity Research

Obesity Hormones in Health and Disease
eLS
Emrah Caylak

Central Dopaminergic Circuitry Controlling Food Intake and Reward: Implications for the Regulation of Obesity
WIREs Systems Biology and Medicine
Zivjena Vuceti and Teresa M. Reyes

Protocols

Overview of Animal Models of Obesity
Current Protocols in Pharmacology
Thomas A. Lutz and Stephen C. Woods

Diet-Induced Models of Obesity (DIO) in Rodents
Current Protocols in Neuroscience
Didier Bagnol, Hussien Al-Shamma, Dominic Behan, Kevin Whelan and Andrew J. Grottick

Dietary Manipulation of Mouse Metabolism
Current Protocols in Molecular Biology
Jerome N. Feige, Marie Lagouge and Johan Auwerx

Further Reading

eLS

WIREs

Current Protocols

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