Obesity: Epidemiology, Pathophysiology, and Preventionby Debasis Bagchi
Pub. Date: 03/26/2006
Publisher: Taylor & Francis
The obesity epidemic has spawned an unlimited array of quick-fix, rapid weight loss plans and unproven pharmaceuticals. Dangerous side effects and rebound weight gain has made the cure seem worse than the syndrome itself and left people uncertain where to turn. The only way to safely deal with the global obesity problem is to develop strategic therapeutic
The obesity epidemic has spawned an unlimited array of quick-fix, rapid weight loss plans and unproven pharmaceuticals. Dangerous side effects and rebound weight gain has made the cure seem worse than the syndrome itself and left people uncertain where to turn. The only way to safely deal with the global obesity problem is to develop strategic therapeutic interventions using safe, natural supplements supported by credible research.
With contributions from pioneers and esteemed leaders in their respective fields Obesity: Epidemiology, Pathophysiology, and Prevention is a comprehensive resource covering a broad range of topics associated with obesity. Divided into eight sections, the text covers epidemiology and pathophysiology, correlating obesity with environmental estrogens, disordered eating, inflammatory responses, and endocrine disruption. Contributions also address neurobiology and neurotransmitters, leptin, ghrelin (the hunger hormone) and molecular genetics.
The book devotes several chapters to obesity and its related degenerative diseases, drug development and adipose-targeted drugs, and the safety of obesity drugs. An expansive portion of the book considers natural, nutritional, and physical approaches to weight management. Taking an evidence based approach, it explores exercise, diet (including vegetarian and Atkin’s diets), gender differences, and caloric restriction, along with research on a wide range of functional foods, nutraceuticals, and natural supplements such as hydroxycitric acid, marine lipids, tea, chitosan, calcium, polyphenolic compounds, trivalent chromium, ephedra, and glucomannan. Special sections on the intricacies of childhood obesity and the benefits of bariatric surgery round out the array of information.
With unparalleled depth of coverage, Obesity: Epidemiology, Pathophysiology, and Prevention provides medical professionals, nutritionists, and researchers with an unprecedented reference for managing obesity.
Table of Contents
SECTION I. INTRODUCTION
Epidemiology of Obesity, D.Giovanna Turconi and Dr. H. Cena
Epidemiology of Obesity: A Global Burden of the New Millennium, G. C. Pain
SECTION II. PATHOPHYSIOLOGY OF OBESITY
Environmental Estrogens, Endocrine Disruption and Obesity, F. S. vom Saal, J. R. Kirkpatric,k and B. L. Coe
Cigarette Smoking, Inflammation and Obesity, S. K Biswas, I. Megson, C. A Shaw, and I. Rahman
Disordered Eating as a Correlate in the Development of Obesity, G. W. Pla.
Role of Neurotransmitters in Obesity Regulation, S.E. Ohia and C. Opere
Neurobiology of Obesity, N. Eikelis
Leptin as a Vasoactive Adipokine: Link between Metabolism and Vasculature, A. Bouloumié, C. A. Curat, A. Miranville, K. Lolmède, and C. Sengenès
Overview on Ghrelin, Appetite and Energy Balance, R. Fernández-Fernández and M. Tena-Sempere
Molecular Genetics of Obesity Syndrome: Role of DNA Methylation, R. S. Dwivedi, A. Sahad, and B. L. Mirkin.
SECTION III. OBESITY AND DEGENERATIVE DISEASES
Oxidative Stress Status in Humans with Metabolic Syndrome, C.Y. Chen and J. B. Blumberg
Obesity and Type 2 Diabetes, S. Yaturu and S. K. Jain
Obesity and Angiogenesis in Cancer: Applications of Angiogenesis Targeted Redox-Based Therapeutics, S. Chatterjee, D. Bagchi, M. Bagchi, and C. K. Sen
Obesity as an Occult Risk Factor for Drug and Chemical Toxicities, G. B. Corcoran
SECTION IV. NOVEL CONCEPT IN OBESITY DRUG DEVELOPMENT
Adipose Drug Targets for the Treatment of Obesity, O. Boss, L. Lehr, and J.P. Giacobino
SECTION V. SAFETY OF OBESITY DRUGS
Safety of Obesity Drugs, A. Gupta and Dr. F.L. Greenway
SECTION VI. NATURAL, NUTRITIONAL AND PHYSICAL APPROACHES OF WEIGHT MANAGEMENT
The Fundamental Role of Physical Activity and Exercise in Weight Management, D. Blatt and C. L. Gostic
Nutritional and Dietary Approaches for Weight Management - An Overview, S. Agarwal
Gender Differences in Body Fat Utilization During Weight Gain, Loss or Maintenance, G.K. Harris and D. J. Baer
Appetite, Body Weight, Health Implications of a Low-Glycemic Load Diet, S. J. Bell, W. Van Ausday, and G. Grochoski
Beyond Obesity Prevention: The Anti-Aging Effects of Caloric Restriction, K. W. Saupe and J. D. Mulligan
Dietary Supplement Carbohydrate Digestion Inhibitors: A Review of the Literature, J. Udani, M. Hardy, and B. Kavoussi
Vegetarian Diets in the Prevention and Treatment of Obesity, Dr. K. T. Knecht, H. Bui, D. Tran, and J. Sabate.
The Atkins Paradigm, A. Robarge and B. W. Downs
Polyphenols from Fruit and Vegetables in Weight Management and Obesity Control, D. Ghosh and M. A Skinner
Chromium (III) in Promoting Weight Loss and Lean Body Mass, M. Bagchi, H. G. Preuss, S. Zafra-Stone, and D. Bagchi
An Overview on (-)-Hydroxycitric Acid in Obesity Regulation, S. Zafra-Stone, M. Bagchi, H. G. Preuss, and D.Bagchi
A Review of the Safety and Efficacy of Citrus aurantium in Weight Management, S. J. Stohs and M. Shara
Conjugated Linoleic Acid (CLA) and Weight Control: From the Biomedical Immune Viewpoint, Z.L. Kong
The Role of Tea in Weight Management, C.Kandaswami
Laboratory and Clinical Studies of Chitosan, H. G. Preuss, D. Bagchi, and G. R. Kaats
Phaseolus vulgaris and Alpha Amylase Inhibition, D. E. Meiss
Role of Glucomannan in Weight Management, B. Swanson and J. K. Keithley
Role of Caralluma fimbriata in Weight Management, R.V. Venkatesh and R. Rajendran
Role of Medium Chain Triglycerides in Weight Management, M. Enig.
Anti-Obesity by Marine Lipids, K. Miyashita
Dairy Foods, Calcium and Weight Management, Dr. M. B. Zemel
Lessons from the Use of Ephedra as a Dietary Supplement, M. Soni, K. Shelk,e and R. Amin
Dietary Supplementation in Weight Loss – A Dietician’s Perspective, B. Wedman-St Louis
SECTION VII. CHILD OBESITY AND PREVENTION
Treatment and Prevention of Childhood Obesity and Associated Metabolic Diseases, M. I Goran, J. N Davies, and L. A Kelly
SECTION VIII. BARIATRIC SURGERY IN WEIGHT MANAGEMENT
Bariatric Surgery in Obesity and Reversal of Metabolic Disorders, M. Manco
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