Obesity: Integrating Physiological, Pathophysiological and Clinical Perspectives

by Javier Gonzalez (Editor)

Overview

Obesity: Integrating Physiological, Pathophysiological and Clinical Perspectives, a volume in Elsevier's Hot Topics in Physiology series, provides coverage across a wide range of physiological disciplines, covering obesity science at a sufficient level to be understood by physiologists who may not be an expert in all subdisciplines, and with an aim of unifying physiological perspectives on obesity. Divided into three sections, the book covers causes of obesity (e.g., regulation of energy balance), the consequences of obesity (e.g., metabolic, disease risk etc.), and strategies to prevent and/or manage obesity (e.g., bariatric surgery, pharmacotherapy, and lifestyle).

This volume is published in association with the International Union of Physiological Sciences (IUPS). It will be of great interest for clinicians, dieticians, exercise physiologists, and molecular biologists.

Product Details

ISBN-13:	9780443219719
Publisher:	Elsevier Science
Publication date:	03/01/2026
Series:	Hot Topics in Physiology
Pages:	300
Product dimensions:	7.50(w) x 9.25(h) x (d)

About the Author

Dr. Gonzalez joined the Department for Health at the University of Bath in 2014 as an Assistant Professor in Human Physiology before being promoted to Associate Professor in 2017 and Professor in 2020. He is also a consultant to sports teams and industry. He is interested in human fuel use, how we get fuel from our diet, burn fuels during exercise; and store fuels when they exceed our requirements. His research group employs a variety of methods to understand human fuel use, including indirect calorimetry, tissue biopsies and stable isotope (IV) infusion and ingestion. In recognition of his research, Dr. Gonzalez received the Julie Wallace Award 2018 from the Nutrition Society. He also serves on the editorial board of The Journal of Physiology and am an Associate Editor for the International Journal of Sport Nutrition & Exercise Metabolism.

Table of Contents

1. Introduction and global context

Causes of obesity
2. Energy balance and energy storage
3. Regulation of energy intake
4. Regulation of energy expenditure
5. Role of the gut microbiome in obesity
6. Genetics of obesity

Consequences of obesity
7. Metabolic implications of obesity
8. Cardiovascular repercussions of obesity
9. Obesity, immunity, and inflammation
10. Obesity and cancer
11. Respiratory consequences of obesity
12. Effects of obesity on reproductive function
13. Implications of obesity in pregnancy
14. Causes and consequences of body fat distribution

Strategies to prevent and manage obesity
15. Role of dietary restriction in obesity prevention and management
16. Role of dietary macronutrient composition in obesity prevention and management
17. Role of physical activity in obesity prevention and management
18. Bariatric surgery for the treatment and management of obesity
19. Pharmacology for the treatment and management of obesity

Conclusions
20. Summary and future perspectives

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From the Publisher

Presents the causes, consequences, and prevention of obesity from a physiological perspective