Optical Mapping of Cardiac Excitation and Arrhythmias / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
Buy Used
Buy Used from BN.com
(Save 28%)
Item is in good condition but packaging may have signs of shelf wear/aging or torn packaging.
Condition: Used – Good details
Used and New from Other Sellers
Used and New from Other Sellers
from $18.00
Usually ships in 1-2 business days
(Save 91%)
Other sellers (Hardcover)
  • All (8) from $18.00   
  • New (4) from $171.42   
  • Used (4) from $18.00   


The recent explosion of knowledge in the cardiovascular field has been fueled by the development of powerful and novel technologies for assessing cardiovascular function and disease. Fluorescent imaging techniques in the heart are a major example. Despite its widespread use in basic research and implications to clinical cardiac electrophysiology, there are no definitive and authoritative sources of information on cardiac optical mapping. This is the first and only book to date that comprehensively, in a single volume, covers all aspects of the technique and application of optical mapping in the heart. Written by leading international experts in the discipline, the book contains the basic principles of optical mapping, including: voltage-sensitive fluorescence, optics, imaging, and high speed computer data acquisition. In addition to providing a primer on basic principles, the book''s four main sections cover applications of optical mapping to our understanding of impulse propagation in the heart, cardiac arrhythmias, and cardiac defibrillation. Commentary is provided throughout the book from leaders in the field of clinical cardiac electrophysiology regarding implications to our understanding of arrhythmia mechanisms in patients. This book is essential for scientists, cardiac clinicians, and trainees of all backgrounds who are interested in state-of-the-art imaging approaches to biology, as well as for the investigator who is thinking about establishing an optical mapping system in his/her lab.

Read More Show Less

Editorial Reviews

From the Publisher
"This unique book...bridges the gap between basic science and clinical electrophysiology."

William C. Roberts
American Journal of Cardiology
Read More Show Less

Product Details

  • ISBN-13: 9780879934811
  • Publisher: Wiley
  • Publication date: 12/28/2001
  • Edition number: 1
  • Pages: 458
  • Product dimensions: 6.30 (w) x 9.30 (h) x 1.10 (d)

Table of Contents


Mark E. Josephson.



Section I. Basic Principles .

Introduction: Optical Mapping of Cardiac Excitation and Arrhythmias: A Primer.

David S. Rosenbaum.

1. Optical Mapping: Background and Historical Perspective.

Guy Salama.

2. Mechanisms and Principles of Voltage-Sensitive Fluorescence.

Leslie M. Loew.

3. Optical Properties of Cardiac Tissue.

William T. Baxter.

4. Optics and Detectors Used in Optical Mapping.

Kenneth R. Laurita and Imad Libbus.

5. Optimization of Temporal Filtering for Optical Transmembrane Potential Signals.

Francis X. Witkowski, Patricia A. Penkoske, and L. Joshua Leon.


Section II. Microscopic Propagation.

Introduction: Unique Role of Optical Mapping in the Study of Propagation and Repolarization.

David S. Rosenbaum.

6. Optical Mapping of Impulse Propagation within Cardiomyocytes.

Herbert Windisch.

7. Optical Mapping of Impulse Propagation between Cardiomyocytes.

Stephan Rohr and Jan P. Kucera.

8. Role of Cell-to-Cell Coupling, Structural Discontinuities, and Tissue Anisotropy in Propagation of the Electrical Impulse.

André G. Kléber, Stephan Rohr, and Vladimir G. Fast.

9. Optical Mapping of Impulse Propagation in the Atrioventricular Node: 1.

Todor N. Mazgalev and Igor R. Efimov.

10. Optical Mapping of Impulse Propagation in the Atrioventricular Node: 2.

Guy Salama and Bum-Rak Choi.

11. Optical Mapping of Microscopic Propagation: Clinical Insights and Applications.

Albert L. Waldo.


Section III. Cardiac Arrhythmias.

Introduction: Unique Role of Optical Mapping in the Study of Cardiac Arrhythmias.

José Jalife.

12. Mapping Arrhythmia Substrates Related to Repolarization: 1. Dispersion of Repolarization.

Kenneth R. Laurita, Joseph M. Pastore, and David S. Rosenbaum.

13. Mapping Arrhythmia Substrates Related to Repolarization: 2. Cardiac Wavelength.

Steven Girouard and David S. Rosenbaum.

14. Video Imaging of Cardiac Fibrillation.

Richard A. Gray and José Jalife.

15. Video Mapping of Spiral Waves in the Heart.

William T. Baxter and Jorge M. Davidenko.

16. Video Imaging of Wave Propagation in a Transgenic Mouse Model of Cardiomyopathy.

Faramarz Samie, Gregory E. Morley, Dhjananjay Vaidya, Karen L. Vikstrom, and José Jalife.

17. Optical Mapping of Cardiac Arrhythmias: Clinical Insights and Applications.

Douglas L. Packer.


Section IV. Cardiac Defibrillation.

Introduction: Unique Role of Optical Mapping in the Study of Cardiac Defibrillation.

José Jalife.

18. Response of Cardiac Myocytes to Electrical Fields.

Leslie Tung.

19. New Perspectives in Electrophysiology from The Cardiac Bidomain.

Shien-Fong Lin and John P. Wikswo, Jr..

20. Mechanisms of Defibrillation: 1. Influence of Fiber Structure on Tissue Response to Electrical Stimulation.

Stephen B. Knisley.

21. Mechanisms of Defibrillation: 2. Application of Laser Scanning Technology.

Stephen M. Dillon.

22. Mechanisms of Defibrillation: 3. Virtual Electrode-Induced Wave Fronts and Phase Singularities; Mechanisms of Success and Failure of Internal Defibrillation.

Igor R. Efimov and Yuanna Cheng.

23. Optical Mapping of Cardiac Defibrillation: Clinical Insights and Applications.

Douglas P. Zipes.


Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)