The Organic Chemistry of Drug Synthesis, Volume 4 / Edition 1

by Daniel Lednicer, Lester A. Mitscher, Gunda I. Georg

Overview

Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Product Details

ISBN-13:	9780471855484
Publisher:	Wiley
Publication date:	01/16/1991
Series:	Organic Chemistry Series of Drug Synthesis , #4
Edition description:	Volume 4 ed.
Pages:	272
Product dimensions:	6.34(w) x 9.63(h) x 0.71(d)

About the Author

Daniel Lednicer, PhD, is the author of several books on drug synthesis and discovery. His career in both the private and public sectors has been devoted to the search for new therapeutic agents. Dr. Lednicer spent two decades at the bench as a chemist at the Upjohn Company. Following that, he served as director of chemical research at Mead Johnson, director of pharmaceutical sciences at Adria Laboratories, and pharmaceutical manager at Analytical Biochemistry Laboratories. Most recently, he was a project officer at the National Cancer Institute.

Lester A. Mitscher, Ph.D., recognized for his research achievements by numerous institutions, serves as a consultant for the National Institutes of Health, among other organizations. Dr. Mitscher is a professor at the University of Kansas and the Victorian College of Pharmacy at Monash University outside Melbourne, Australia. Victoria Dolby Toews, MPH, a veteran freelance researcher and writer, has written and coauthored many books on health and wellness. She lives in the Pacific Northwest.

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Table of Contents

Aliphatic and Alicyclic Compounds.

Monocyclic Aromatic Compounds.

Polycyclic Aromatic Compounds and Their Reduction Products.

Steroids.

Five-Membered Ring Heterocycles.

Six-Membered Ring Heterocycles.

Five-Membered Ring Benzofused Heterocycles.

Six-Membered Ring Benzofused Heterocycles.

Bicyclic Fused Heterocycles.

beta-Lactam Antibiotics.

Miscellaneous Heterocycles.

Indexes.

Editorial Reviews

The series meets the needs of practitioners in the field who seek a quick overview of the synthetic routes that have been used to access specific classes of therapeutic agents. Volume 5 covers the literature on the synthesis of medicinal agents from 1988 to 1993. The materials are arranged and discussed in terms of chemical structure; thus, the preparation and detailed organic chemistry of the classes are presented in a unified way. Only drugs which have been granted a US Adopted Name are included. For synthetic organic, pharmaceutical, medicinal, and heterocyclic chemists. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Booknews

"The book is up-to-date with regard to the drugs presented and has the potential to be a good resources for experienced researchers in drug design…" (Journal of the American Chemical Society, March 12, 2008)

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