Organic Chemistry / Edition 6

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Overview

The text continues to build on its reputation of providing students with a progressive introduction to organic chemistry. One of the most outstanding features of the new edition is an increased and more thorough coverage of mechanisms. ORGANIC CHEMISTRY, Third edition is clearly written and provides students with many more real life examples of organic chemistry, especially in the areas of bio-organic chemistry and medicinal chemistry.
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Editorial Reviews

From the Publisher
"I find that the BFIA text is very sound pedagogically. Essential concepts are carefully and intuitively explained. Take, for example, the essential survival skill of using curved arrow notation and applying this to the understanding or reaction mechanisms. The authors break this skill down into its simplest components and build from there. This starts with the definition of an electron source and an electron sink. From these definitions, students readily grasp the physical driving force behind the flow of electrons in organic reactions in addition to mastering the use of curved arrow notation. The "how to" sections provide an abundance of detail and effectively break traditionally challenging concepts into logical, readily digested portions. Finally, the sections entitled "Chemical Connections" provide very relevant, up-to-date tie-ins of the subject material to matters of chemical, biological and pharmacological interest."

"I find the problem set at the end of each chapter superb. I believe this is a culmination of hard work over the years by the authors in this area. His treatment of resonance is quite good but the Organometallics covered in Chapter 24 is also second to none! These are the strongest features of the book."

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Product Details

Meet the Author

William H. Brown is emeritus professor of chemistry at Beloit College, where he was twice named Teacher of the Year. His teaching responsibilities include organic chemistry, advanced organic chemistry, and, more recently, special topics in pharmacology and drug synthesis. He received his Ph.D. from Columbia University under the direction of Gilbert Stork and did postdoctoral work at California Institute of Technology and the University of Arizona. He is a coauthor on INTRODUCTION TO GENERAL, ORGANIC AND BIOCHEMISTRY, 10e (Cengage Learning/Brooks Cole).

Brent L. Iverson received his Ph.D. from Stanford University in 1982 and currently teaches at University of Texas, Austin. He is a distinguished teacher and respected researcher. Iverson's research group has developed methods for recombinant antibody or enzyme cloning and has directed its evolution. In collaboration with the Georgiou group, he pioneered a novel E. coli surface expression/FACS selection technology that has allowed the group to enhance antibody affinity.

Eric Anslyn is the Norman Hackerman Professor of Chemistry at The University of Texas at Austin. Highly respected in organic chemistry, he earned his Ph.D. from the California Institute of Technology and has won numerous teaching awards. Anslyn's research focuses on the cutting-edge area of bioorganic chemistry.

Christopher S. Foote received his B.S. in 1957 from Yale University and his Ph.D. in 1962 from Harvard University. His scholarly credits include Sloan Fellow 1965-1967; Guggenheim Fellow 1967-1968; ACS Baekland Award, 1975; ACS Cope Scholar, 1994; Southern California Section ACS Tolman Medal, 1996; President, American Society for Photobiology, 1988-1989; and Senior Editor, ACCOUNTS OF CHEMICAL RESEARCH. He was Professor of Chemistry at UCLA.

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Table of Contents

1. Covalent Bonding and Shapes of Molecules. 2. Alkanes and Cyclokanes. 3. Chirality. 4. Acids and Bases. 5. Alkenes I. 6. Alkenes II. 7. Haloalkanes, Alkenes, And Arenes. 8. Nucleophilic Substitution And ß- limination. 9. Alcohols and Thiols. 10. Alkynes. 11. Ethers, Sulfides, and Epoxides. 12. Infared Spectroscopy. 13. Nuclear Magnetic Resonance Spectroscopy. 14. Mass Spectrometry. 15. Organometallic Compounds. 16. Aldehydes and Ketones. 17. Carboxylic Acid. 18. Functional Derivatives of Carboxylic Acids. 19. Enolate Anions and Enamines. 20. Aromatics I - Benzene And Its Derivatives. 21. Aromatics II - Reactions of Benzene And Its Derivatives. 22. Amines. 23. Conjugated Systems. Interchapter. Medicinal Chemistry—Problems in Organic Synthesis. 24. Organic Polymer Chemistry. 25. Carbohydrates. 26. Lipids. 27. Amino Acids and Proteins. 28. Nucleic Acids. 29. The Organic Chemistry of Metabolism. Appendix 1. Thermodynamics and the Equilibrium Constant. Appendix 2. The Major Classes of Organic Acids. Appendix 3. Bond Dissociation Energies. Appendix 4. Characteristic 1H-NMR Chemical Shifts. Appendix 5. Characteristic 13C-NMR Chemical Shifts. Appendix 6. Characteristic Infrared Absorption Frequencies. Appendix 7. Regents and Their Uses. Appendix 8. Summary of Methods for the Synthesis of Functional Groups and new Carbon-Carbon Bonds. Appendix 9. Electrostatic Potential Maps. Glossary. Index.
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