Organic Synthesis: Strategy and Control / Edition 1by Paul Wyatt, Stuart Warren
Pub. Date: 06/15/2007
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds/i>/b>/i>… See more details below
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice.
The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy.
- A comprehensive, practical account of the key concepts involved in synthesising compounds
- Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations
- Focuses on reactions that really work rather than those with limited application
- Contains extensive, up-to-date references in each chapter
Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
- Publication date:
- Edition description:
- New Edition
- Product dimensions:
- 7.40(w) x 9.70(h) x 2.00(d)
Table of ContentsA: Introduction:Selectivity.
1.Planning Organic Syntheses: Tactics, Strategy, and Control.
3.Regioselectivity: Controlled Aldol Reactions.
4.Stereoselectivity: Stereoselective Aldol Reactions.
5.Alternative Strategies for Enone Synthesis.
6.Choosing a Strategy : The Synthesis of cyclopentenones.
B: Making Carbon-Carbon Bonds.
7.The Ortho Strategy for Aromatic Compounds.
8.δ-Complexes of Metals.
9.Controlling the Michael Reaction.
10.Specific Enol Equivalents.
14.Acyl Anion Equivalents.
C: Carbon-Carbon Double Bonds.
15.Synthesis of Double Bonds of Defined Stereochemistry.
16.Stereo-Controlled Vinyl Anion Equivalents.
17.Electrophilic Attack on Alkenes.
18.Vinyl Cations: Palladium-Catalysed C–C Coupling.
19.Allyl Alcohols: Allyl Cation Equivalents (and More).
20.Control of Stereochemistry — Introduction.
21Controlling Relative Stereochemistry.
23.The Chiral Pool.
24.Asymmetric Induction I: Reagent-Based Strategy.
25.Asymmetric Induction II: Asymmetric Catalysis: Formation of C-O and C-N Bonds.
26.Asymmetric Induction III: Asymmetric Catalysis: Formation of C-H and C-C Bonds.
27.Asymmetric Induction IV: Substrate-Based Strategy.
29.Enzymes: Biological Methods in Asymmetric Synthesis.
30.New Chiral Centres fromOld.
31.Strategy of Asymmetric Synthesis.
E: Functional Group Strategy.
32.Functionalisation of Pyridine.
33.Oxidation of Aromatic Compounds, Enols and Enolates.
34.Functionality and Pericyclic Reactions: Nitrogen Heterocycles by Cycloadditions and Sigmatropic Rearrangements.
35.Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms.
36.Tandem Organic Reactions.
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