Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness
An intellectually daring and deeply intimate exploration of how genetics complicate our ideas about blame, punishment and moral responsibility—from acclaimed psychologist and author of The Genetic Lottery, Kathryn Paige Harden.

As one of the world’s leading scientists examining how our DNA shapes differences in temperament, temptation and behaviour, Kathryn Paige Harden has seen firsthand how we—in public and in our most private relationships—continue to struggle with the ancient tensions between nature and nurture, freedom and constraint, the desire to punish and the longing to forgive.

In Original Sin, she weaves together insights from her own experience as a daughter, mother, wife, and scientist with cutting-edge research in genetics and psychology to grapple with some of the most important questions in modern life: How do we take responsibility for the people we become, knowing how we are shaped by both biology and experience? How should we respond when people hurt each other—or themselves? And has science made guilt obsolete?

Navigating the psychological and biological terrain of addiction, antisocial behaviour and violence, Harden confronts the discomforting ways science unsettles our understanding of wrongdoing and choice. In doing so she asks us not to absolve, but to reckon differently with notions of fairness and blame. A revelatory inquiry into the uneasy space where human behaviour meets inherited biology, Original Sin challenges us to imagine a more humane vision of accountability—for ourselves and for one another.
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Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness
An intellectually daring and deeply intimate exploration of how genetics complicate our ideas about blame, punishment and moral responsibility—from acclaimed psychologist and author of The Genetic Lottery, Kathryn Paige Harden.

As one of the world’s leading scientists examining how our DNA shapes differences in temperament, temptation and behaviour, Kathryn Paige Harden has seen firsthand how we—in public and in our most private relationships—continue to struggle with the ancient tensions between nature and nurture, freedom and constraint, the desire to punish and the longing to forgive.

In Original Sin, she weaves together insights from her own experience as a daughter, mother, wife, and scientist with cutting-edge research in genetics and psychology to grapple with some of the most important questions in modern life: How do we take responsibility for the people we become, knowing how we are shaped by both biology and experience? How should we respond when people hurt each other—or themselves? And has science made guilt obsolete?

Navigating the psychological and biological terrain of addiction, antisocial behaviour and violence, Harden confronts the discomforting ways science unsettles our understanding of wrongdoing and choice. In doing so she asks us not to absolve, but to reckon differently with notions of fairness and blame. A revelatory inquiry into the uneasy space where human behaviour meets inherited biology, Original Sin challenges us to imagine a more humane vision of accountability—for ourselves and for one another.
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Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness

Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness

by Kathryn Paige Harden
Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness

Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness

by Kathryn Paige Harden

Hardcover

$30.00 
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Overview

An intellectually daring and deeply intimate exploration of how genetics complicate our ideas about blame, punishment and moral responsibility—from acclaimed psychologist and author of The Genetic Lottery, Kathryn Paige Harden.

As one of the world’s leading scientists examining how our DNA shapes differences in temperament, temptation and behaviour, Kathryn Paige Harden has seen firsthand how we—in public and in our most private relationships—continue to struggle with the ancient tensions between nature and nurture, freedom and constraint, the desire to punish and the longing to forgive.

In Original Sin, she weaves together insights from her own experience as a daughter, mother, wife, and scientist with cutting-edge research in genetics and psychology to grapple with some of the most important questions in modern life: How do we take responsibility for the people we become, knowing how we are shaped by both biology and experience? How should we respond when people hurt each other—or themselves? And has science made guilt obsolete?

Navigating the psychological and biological terrain of addiction, antisocial behaviour and violence, Harden confronts the discomforting ways science unsettles our understanding of wrongdoing and choice. In doing so she asks us not to absolve, but to reckon differently with notions of fairness and blame. A revelatory inquiry into the uneasy space where human behaviour meets inherited biology, Original Sin challenges us to imagine a more humane vision of accountability—for ourselves and for one another.

Product Details

ISBN-13: 9780593447628
Publisher: Random House Publishing Group
Publication date: 03/03/2026
Pages: 320
Product dimensions: 5.50(w) x 8.25(h) x 0.81(d)

About the Author

Kathryn Paige Harden is a professor in the department of psychology at UT, where she leads the Developmental Behavior Genetics lab. Harden received her Ph.D. in clinical psychology from the University of Virginia and completed her clinical internship at McLean Hospital/Harvard Medical School. She has been awarded by the American Psychological Association for her distinguished scientific contributions to the study of genetics and human individual differences.
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