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Doody's Review ServiceReviewer: Riad Barmada, MD (University of Illinois at Chicago College of Medicine)
Description: This is a brief overall review of tissue engineering and regeneration of musculoskeletal tissues and its clinical application as related to orthopedic surgery.
Purpose: The purpose is to introduce this relatively new technique to orthopedic surgeons and residents, as well as to scientists interested in skeletal related research.
Audience: Orthopedic surgeons, residents and researchers are the intended audience.
Features: The authors first present basic principles of tissue engineering and regeneration of skeletal tissues, various factors that encourage morphogenesis and biodegenerable scaffolds that could be used to accomplish tissue regeneration. The second part of the book is dedicated to clinical application of this method in particular regeneration of cartilage, meniscus, intervertebral disc, ligaments, tendons, and muscles.
Assessment: Tissue engineering is relatively a new method in treating afflictions of the musculoskeletal system and until recently research and clinical applications were restricted to prosthetic replacement of various parts of the skeletal system. Tissue regeneration and morphogenesis is the future treatment modality for many orthopedic-related diseases. This book provides a window for orthopedic surgeons and residents into a new discipline which is possibly going to be a major factor in the practice of orthopedic surgery.