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Osteoporosis in Focus / Edition 1

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More About This Textbook


Osteoporosis is a major healthcare problem, affecting the lives of many individuals worldwide. In the UK alone, over 200,000 osteoporosis-related fractures occur annually - a figure that is set to increase as the population ages. Pharmacists see many patients with osteoporosis, and thus will benefit from a deeper understanding of this disease. Osteoporosis in Focus contains a clear, concise discussion of osteoporosis and reviews the role of the pharmacist in counselling patients on their illness, lifestyle and medicines. Chapter topics include prevention, monitoring the condition, interventions, drug treatment, hormone replacement therapy, bisphosphonates, and screening. The third book of the 'in Focus' series, Osteoporosis in Focus should be read by all pharmacists as well as by healthcare professionals with an interest in osteoporosis.

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Product Details

  • ISBN-13: 9780853694830
  • Publisher: Pharmaceutical Press
  • Publication date: 4/1/2004
  • Edition number: 1
  • Pages: 288
  • Product dimensions: 6.40 (w) x 9.50 (h) x 0.70 (d)

Table of Contents

Preface xi
Acknowledgements xiii
About the author xiv
Abbreviations xvi
1 Introduction 1
2 Osteoporosis 5
Definition 5
Physiological background 7
Epidemiology 19
Signs and symptoms 22
Types of conditions 22
Differential diagnosis 24
3 Prevention of osteoporosis 27
General health 27
Genetic factors 31
Lifestyle factors 34
Menopause 36
Fractures 38
Self-help groups 41
4 Lifestyle factors 43
Alcohol 46
Cigarette smoking 49
Diet 53
Exercise 54
Other contributing factors 56
5 Monitoring the condition 59
Diagnosis 59
Radiological techniques 60
Biochemical markers 69
Bone biopsy 75
6 Clinical interventions 77
Medical interventions for osteoporosis 78
Surgical interventions for osteoporosis 90
7 Drug treatments 95
Prevention 98
Active treatment 105
Other therapies 109
8 Calcium and vitamin D 111
Calcium 111
Vitamin D 118
Combination therapy 123
Drug interactions 124
9 Hormone replacement therapy 127
Menopause 127
Drug therapy 132
Choice of drug and dose 135
Timing of replacement therapy 137
Selective oestrogen receptor modulators (SERM) 143
10 Bisphosphonates 145
Theoretical basis of bone loss 145
Drug handling 148
Fracture rate 150
Treatment regimens 151
Indications for treatment 152
Individual drugs 153
11 The future 163
Population demographics 163
Lifestyle changes 164
Health factors 168
Monitoring 169
Medical interventions 170
Health promotion 174
12 Osteoporosis screening 179
At-risk groups 181
Clinical management 187
Opportunities for screening 190
Treatment choices 192
Clinical audit 193
13 Pharmaceutical care of the osteoporotic patient 195
Pharmaceutical care 195
Pharmaceutical care in osteoporosis 198
Pharmaceutical care projects 205
Glossary 209
Recommended reading 215
Index 217
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