Osteoporosis, Two-Volume Set

Overview

Osteoporosis is the most comprehensive, authoritative reference on this disease. Some of the topics covered include basic biology, anatomy, physiology, pathophysiology, preclinical issues, experimental medicine, management, and therapeutics. Written by renowned experts in this field, this book is a must-have for the researcher, the academic clinician, or anyone in the field ...
See more details below
Available through our Marketplace sellers.
Other sellers (Hardcover)
  • All (6) from $21.33   
  • New (4) from $125.00   
  • Used (2) from $21.33   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$125.00
Seller since 2014

Feedback rating:

(164)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
$146.68
Seller since 2010

Feedback rating:

(55)

Condition: New
"New, ships through UPS and DHL. Excellent customer service. Satisfaction guaranteed!! "

Ships from: STERLING HEIGHTS, MI

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
$169.54
Seller since 2014

Feedback rating:

(0)

Condition: New
Hardcover New in new dust jacket. Brand New US edition, 3-5 days shipping!

Ships from: Sausalito, CA

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$617.02
Seller since 2010

Feedback rating:

(271)

Condition: New
Brand New. US Edition Book. We do not ship to Military Addresses. Fast Shipping with Order Tracking. For Standard Shipping 7-8 business days & Expedite Shipping 4-6 business days, ... after shipping. Read more Show Less

Ships from: Sugar Land, TX

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
Page 1 of 1
Showing All
Close
Sort by
Sending request ...

Overview

Osteoporosis is the most comprehensive, authoritative reference on this disease. Some of the topics covered include basic biology, anatomy, physiology, pathophysiology, preclinical issues, experimental medicine, management, and therapeutics. Written by renowned experts in this field, this book is a must-have for the researcher, the academic clinician, or anyone in the field of bone biology.

Key Features
* The source on osteoporosis
* Written by expert investigators in their respective fields
* Each chapter provides timely, comprehensive, and scholarly discussion
* Fully illustrated in color and black & white
* Covers everything from basic anatomy and physiology to diagnosis, management and treatment

Audience: Researchers, academic clinicians, and libraries.

Read More Show Less

Editorial Reviews

From the Publisher
Praise for the first edition:

"...interesting, comprehensive and up-to-date: each chapter has something new and important to say...Whichever direction one chooses to approach this monumental work I predict it will be worthwhile"
-JOURNAL OF BONE AND JOINT SURGERY

"...a textbook focused solely on this condition and encompassing this diversity of research has been lacking. This book does a terrific job of filling the gap. It contains 70 chapters grouped in six sections...All the chapters are authoritative and include up-to-date references...Osteoporosis is quite comprehensive; indeed, topics that typically receive brief treatment elsewhere (osteoporosis in minority groups and in men) receive entire chapters here...The book also covers relevant methodologic concepts, no doubt reflecting the editors desire to make the material accessible to readers with other primary research interests."
-THE NEW ENGLAND JOURNAL OF MEDICINE

Praise for the second edition:

"...well edited and the chapters are clearly cross-referenced...a helpful reference for any scientist or clinician with an interest in the field."
-THE GERONTOLOGIST

Melissa Cavaghan
This book comprehensively explores the topic of osteoporosis from basic biology underlying normal and disease states to clinical evaluation and therapeutics. "The purpose is to provide the first thorough discussion of osteoporosis with enough depth and breadth to make it useful for both the basic investigator and the clinician. They successfully synthesize a foundation of biology, mechanics, epidemiology, and biochemistry to describe a complex condition and then expand upon this to describe varied disease states and clinical approaches to management. "It is aimed at both the researcher and the practitioner who deal with osteoporosis. It is probably must useful to the endocrinologist, but it is also of pertinent interest to orthopedists, rheumatologists, and general practitioners, especially of the elderly. "The text is liberally illustrated, with a good balance of histologic reproductions (some in color) and diagrammatic illustration of biologic principles. It is fully and currently referenced. The authors' method of organization makes it extremely easy to find information very quickly. It is also extensively cross referenced, so all pertinent information is easily available. "This is a comprehensive reference text of osteoporosis. If read cover to cover, the reader would be educated first on basic skeletal biology, including embryology, mechanics, and biochemistry, then on epidemiology and pathophysiology, and finally to the clinical disease states of osteoporosis, with emphasis on the varied other medical conditions that complicate or contribute to the development of osteoporosis. The basic and clinical sections are kept distinctly separate, but each discussion is comprehensiveand stands alone. The authors give a thorough but concise historical review of the research leading up to current understanding in the field and provide direction for future research. It is so clearly written and organized that it can be used quickly and efficiently as a reference text but is also accessible to students and others with a minimal background in endocrinology.
From The Critics
Reviewer:Melissa K. Cavaghan, MD(Indiana University School of Medicine)
Description:This book comprehensively explores the topic of osteoporosis from basic biology underlying normal and disease states to clinical evaluation and therapeutics.
Purpose:The purpose is to provide the first thorough discussion of osteoporosis with enough depth and breadth to make it useful for both the basic investigator and the clinician. They successfully synthesize a foundation of biology, mechanics, epidemiology, and biochemistry to describe a complex condition and then expand upon this to describe varied disease states and clinical approaches to management.
Audience:It is aimed at both the researcher and the practitioner who deal with osteoporosis. It is probably must useful to the endocrinologist, but it is also of pertinent interest to orthopedists, rheumatologists, and general practitioners, especially of the elderly.
Features:The text is liberally illustrated, with a good balance of histologic reproductions (some in color) and diagrammatic illustration of biologic principles. It is fully and currently referenced. The authors' method of organization makes it extremely easy to find information very quickly. It is also extensively cross referenced, so all pertinent information is easily available.
Assessment:This is a comprehensive reference text of osteoporosis. If read cover to cover, the reader would be educated first on basic skeletal biology, including embryology, mechanics, and biochemistry, then on epidemiology and pathophysiology, and finally to the clinical disease states of osteoporosis, with emphasis onthe varied other medical conditions that complicate or contribute to the development of osteoporosis. The basic and clinical sections are kept distinctly separate, but each discussion is comprehensive and stands alone. The authors give a thorough but concise historical review of the research leading up to current understanding in the field and provide direction for future research. It is so clearly written and organized that it can be used quickly and efficiently as a reference text but is also accessible to students and others with a minimal background in endocrinology.
Booknews
Once a curiosity to a few endocrinologists or rheumatologists, osteoporosis has become (during the past two decades) a major focus of investigators and clinicians in fields as diverse as mechanical engineering, pediatrics, and epidemiology. In this hefty reference, 70 contributions cover all aspects of the subject, including the effects of numerous genetic and environmental factors, structural and biomechanical underpinnings, ethnoepidemiology, cellular mechanisms, radiologic assessment, clinical descriptions, and therapeutics. Annotation c. Book News, Inc., Portland, OR (booknews.com)

5 Stars! from Doody
Read More Show Less

Product Details

  • ISBN-13: 9780124708624
  • Publisher: Elsevier Science
  • Publication date: 9/11/2001
  • Edition description: REV
  • Edition number: 2
  • Pages: 1672
  • Product dimensions: 9.32 (w) x 11.81 (h) x 4.38 (d)

Meet the Author

Dr. Marcus is Professor-Emeritus, Stanford University, where he served on the full-time medical faculty for almost 25 years, before joining the Emeritus faculty in 2001. At Stanford, he was located at the Veterans Affairs Medical Center, Palo Alto California, where he served as Director of the Aging Study Unit of the Geriatrics Research, Education, & Clinical Center from 1982-2001. Dr. Marcus enjoyed a long career as a clinical investigator in the fields of bone and mineral metabolism and osteoporosis medicine. His own research interests included diagnosis and therapy of primary hyperpara-thyroidism, interactions of the parathyroid-vitamin D axis with estrogen, age-related changes in the growth hormone-IGF axis, effects of growth hormone replacement for older men and women, metabolic and musculoskeletal effects of resistance exercise in older men and women, adolescent bone acquisition, and osteoporosis therapeutics. Dr. Marcus’ laboratory was a study site for many of the pivotal clinical trials in the osteoporosis field. These include the NIH Post-menopausal Estrogen/Progestin Interventions Trial (PEPI), Merck’s Fracture Intervention Trial (FIT), Lilly’s Multiple Outcomes of Raloxifene Intervention (MORE), and Lilly’s registration trial of recombinant PTH(1-34) in the treatment of postmenopausal women with osteoporosis. In 2001. Dr. Marcus joined the US Affiliate of Eli Lilly & Company to support Lilly’s program in Osteoporosis and Skeletal Medicine. From 2003 until his retirement from Lilly in 2008, Dr. Marcus was the lead physician for the Forteo team at Lilly. He has published more than 150 research papers, editorials, and reviews. Dr. Marcus served as President of the American Society for Bone & Mineral Research in 2000-2001.
Read More Show Less

Table of Contents

Contributors
Preface

VOLUME 1
Part I Introduction to Normal Bone Physiology and Pathophysiology

Chapter 1 The Bone Organ System: Form and Function
Cassandra A. Lee and Thomas A. Einhorn

Chapter 2 Osteoblast Biology
Jane B. Lian and Gary S. Stein

Chapter 3 Osteoclast Biology
F. Patrick Ross and Steven L. Teitelbaum

Chapter 4 The Biochemistry of Bone
Jayashree A. Gokhale, Pamela Gehron Robey, and Adele L. Boskey

Chapter 5 Developmental Biology of Bone
Anthony M. Reginato, Wenfang Wang, and Bjorn R. Olsen

Chapter 6 Mouse Genetics as a Tool to Study Bone Development and Physiology
Millan S. Patel and Gerard Karsenty

Chapter 7 Parathyroid Hormone and Parathyroid Hormone-Related Protein
Robert A. Nissenson

Chapter 8 Calcitonin
Ana O. Hoff, Gilbert J. Cote, and Robert F. Gagel

Chapter 9 Vitamin D: Biology, Action, and Clinical Implication
David Feldman, Peter J. Malloy, and Coleman Gross

Chapter 10 Regulation of Bone Cell Function by Estrogens
Barry S. Komm and Peter V. N. Bodine

Chapter 11 Skeletal Biology of Androgens
Kristine M. Wiren and Eric S. Orwoll

Chapter 12 Coupling of Bone Resorption and Formation during Bone Remodeling
Thomas J. Martin and Gideon A. Rodan

Chapter 13 Cytokines and Bone Remodeling
Gregory R. Mundy, Babatunde Oyajobi, Kathy Traianedes, Sarah Dallas, and Di Chen

Chapter 14 Bone Growth Factors
Xuezhong Qin, Reinhard Gysin, Subburaman Mohan, and David J. Baylink

Chapter 15 Skeletal Heterogeneity and the Purposes of Bone Remodeling: Implications for the Understanding of Osteoporosis
A. M. Parfitt

Chapter 16 Basic Biology of Bisphosphonates
H. Fleisch

Part II Structure and Biomechanics

Chapter 17 Skeletal Development: Mechanical Consequences of Growth, Aging, and Disease
Marjolein C. H. van der Meulen, Dennis R. Carter, and Gary S. Beaupré

Chapter 18 Inhibition of Osteopenia by Biophysical Intervention
Clinton T. Rubin and Kenneth J. McLeod

Chapter 19 Biomechanics of Age-Related Fractures
Mary L. Bouxsein

Part III Epidemiology and Risk Factors

Chapter 20 Introduction to Epidemiologic Methods
Jennifer L. Kelsey and MaryFran Sowers

Chapter 21 Magnitude and Impact of Osteoporosis and Fractures
L. Joseph Melton III and Cyrus Cooper

Chapter 22 Race, Ethnicity, and Osteoporosis
Marie Luz Villa, Lorene Nelson, and Dorothy Nelson

Chapter 23 Epidemiology of Osteoporosis Fractures: The European Experience
Chris de Laet and Jonathan Reeve

Chapter 24 Bone Mineral Acquisition in Utero, during Infancy, and throughout Childhood
Bonny Specker, Ran Namgung, and Reggie C. Tsang

Chapter 25 Bone Acquisition in Adolescence
Jean-Philippe Bonjour and Rene Rizzoli

Chapter 26 Genetics and Genomics of Osteoporosis
André G. Uitterlinden, Johannes P. T. M. van Leeuwen, and Huibert A. P. Pols

Chapter 27 Nutrition and Risk for Osteoporosis
Robert P. Heaney

Chapter 28 Physical Activity and Osteoporosis
Belinda R. Beck, Janet Shaw, and Christine M. Snow

Chapter 29 Premenopausal Reproduction and Hormonal Characteristics and Risk for Osteoporosis
MaryFran Sowers

Chapter 30 Postmenopausal Endogenous and Exogenous Hormones, Degree of Obesity, Thiazide Diuretics, and Risk of Osteoporosis
Jane A. Cauley and Loran M. Salamone

Chapter 31 The Effects of Tobacco and Alcohol Use on Bone
Ego Seeman

Chapter 32 Falls as Risk Factors for Fractures
Anne Schwartz, Elizabeth Capezuti, and Jeane Ann Grisso

Chapter 33 Assessing Fracture Risk
Charles W. Slemenda, C. Conrad Johnston, and Siu L. Hui

Chapter 34 Outcomes of Osteoporotic Fractures
Elizabeth Barrett-Conner and Gail Greendale

VOLUME 2
Part IV Pathophysiology

Chapter 35 The Nature of Osteoporosis
Robert Marcus and Sharmilla Majumder

Chapter 36 Local and Systemic Factors in the Pathogenesis of Osteoporosis
Lawrence R. Raisz

Chapter 37 Animal Models for in Vivo Experimentation in Osteoporosis Research
Donald B. Kimmel

Chapter 38 The TypeI/Type II Model for Involutional Osteoporosis: Update and Modification Based on New Observations
B. Lawrence Riggs, Sundeep Khosla, and L. Joseph Melton III

Chapter 39 Bone Remodeling Findings in Osteoporosis
Robert R. Recker and M. Janet Barger-Lux

Chapter 40 The Role of Parathyroid Hormone and Vitamin D in the Pathogenesis of Osteoporosis
John P. Bilezikian and Shonni J. Silverberg

Chapter 41 Postmenopausal Osteoporosis: How the Hormonal Changes of Menopause Cause Bone Loss
Roberto Pacifici

Chapter 42 Osteoporosis in Men: Epidemiology, Pathophysiology, and Clinical Characterization
Eric S. Orwoll and Robert F. Klein

Chapter 43 Osteoporosis in Childhood and Adolescence
Laura K. Bachrach

Chapter 44 Glucocorticoid-Induced Osteoporosis: Basic Pathological Mechanisms, Clinical Features, and Management in the New Millennium
Gary M. Leong, Jacqueline R. Center, N. Kathryn Henderson, and John A. Eisman

Chapter 45 Familial Osteoporosis
Alan L. Burshell and Steven R. Smith

Chapter 46 Immobilization Osteopenia
B. Jenny Kiratli

Chapter 47 Thyroid Hormone and the Skeleton
Daniel Baran

Chapter 48 Osteoporosis in Gastrointestinal, Pancreatic, and Hepatic Diseases
Daniel D. Bikle

Chapter 49 Primary Hyperparathyroidism and Hyperparathyroid Bone Disease
Lorraine A. Fitzpatrick and Hunter Heath III

Chapter 50 Osteogenesis Imperfecta and Other Defects of Bone Development as Occasional Causes of Adult Osteoporosis
Jay R. Shapiro

Chapter 51 Osteoporosis Secondary to Illnesses and Medications
Adina Schneider and Elizabeth Shane

Chapter 52 Transplantation Osteoporosis
Sol Epstein and Elizabeth Shane

Chapter 53 Osteoporosis Associated with Pregnancy
Lynn Kohlmeier and Robert Marcus

Chapter 54 Osteoprosis Associated with Rheumatologic Disorders
Steven R. Goldring

Chapter 55 Oral Bone Loss and Systemic Osteopenia
Marjorie K. Jeffcoat, Michael S. Reddy, and Arthur A. Decarlo

Part V Evaluation and Management

Chapter 56 Localized Osteoporosis
D. J. Schurman, W. J. Maloney, and R. L. Smith

Chapter 57 The Evaluation of the Patient with Osteoporosis or at Risk for Osteoporosis
Michael Kleerekoper

Chapter 58 Imaging of Osteoporosis
Michael Jergas and Harry K. Genant

Chapter 59 Clinical Use of Bone Densitometry
Kenneth G. Faulkner

Chapter 60 Biochemical Markers of Bone Turnover in Osteoporosis
P. Garnero and P. D. Delmas

Chapter 61 Osteoporosis and Its Nonskeletal Consequences: Their Impact on Treatment Decisions
Deborah T. Gold, Kenneth W. Lyles, Kathy M. Shipp, and Marc K. Drezner

Chapter 62 An Orthopedic Perspective of Osteoporosis
Michael H. Heggeness and Kenneth B. Mathis

Chapter 63 Clinical Use of Bone Biopsy
P. Chavassieux, M. Arlot, and P. J. Meunier

Part VI Pharmacology and Therapeutics

Chapter 64 Design Considerations for Clinical Investigations of Osteoporosis
Robert P. Heaney

Chapter 65 Development and Evaluation of New Drugs for Osteoporosis
Henry Bone

Chapter 66 Evidence-Based Decision Making in Osteoporosis
Ann B. Cranney and Gordon H. Guyatt

Chapter 67 The Role of Calcium in the Treatment of Osteoporosis
Bess Dawson-Hughes

Chapter 68 Vitamin D and Its Metabolites in the Management of Osteoporosis
Ian R. Reid

Chapter 69 Estrogens and Osteoporosis
Robert Lindsay and Felicia Cosman

Chapter 70 Selective Estrogen Receptor Modulators (SERMs)
Ethel S. Siris and Douglas B. Muchmore

Chapter 71 Phytoestrogen and Other Phytochemical Effects on Bone
Richard Prince

Chapter 72 Bisphosphonates in the Management of Postmenopausal Osteoporosis
Socrates E. Papapoulous

Chapter 73 Calcitonin
Roberto Civitelli

Chapter 74 Fluoride Therapy for Osteoporosis
K.-H. William Lau and David J. Baylink

Chapter 75 A New Perspective on Fluoride Therapy
Charles Y. C. Pak

Chapter 76 Androgens and Andogenic Progestins
Sundeep Khosla

Chapter 77 Treatment with PTH Peptides
Lis Mosekilde and Jonathan Reeve

Chapter 78 Growth Hormone and Insulin-Like Growth Factors: Potential Applications and Limitations in the Management of Osteoporosis
Christian Wüster and Clifford Rosen

Chapter 79 New Approaches to Osteoporosis Therapeutics
S. Aubrey Stoch, Michael Chorev, and Michael Rosenblatt

Index

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)