Oxygen Radicals and the Disease Process / Edition 1

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This book provides a detailed investigation into the evidence implicating oxygen radicals in the etiology of eleven different human diseases or conditions. World renowned experts from each discipline review the data supporting this involvement, and discuss the full implications that result. Topics covered include Alzheimer's disease, cerebral ischemia, rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, ARDS, critical care medicine and cancer. This book not only provides an invaluable resource for those seeking up to date information on the evidence supporting the involvement of oxygen radicals in human disease, but also instigates theoretical discussion of future research endeavors.
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Product Details

  • ISBN-13: 9789057022265
  • Publisher: Taylor & Francis
  • Publication date: 3/18/1998
  • Edition number: 1
  • Pages: 282
  • Product dimensions: 7.00 (w) x 10.10 (h) x 0.88 (d)

Table of Contents

List of Contributors
1 Introduction: Free Radicals and Human Disease - Trick or Treat? 1
2 Oxygen Free Radical Involvement in Cerebral Ischemia/Reperfusion Injury 15
3 Electron Paramagnetic Resonance Studies of Amyloid [beta]-Peptide- and Ischemia/Reperfusion-Associated Oxygen Free Radicals and the Membrane Damage they cause: Relevance to Alzheimer's Disease and Stroke 41
4 Oxygen Radicals and Aging 65
5 Free Radicals in Rheumatoid Arthritis: Redox Regulation of Gene Transcription and Proteolytic Tissue Destruction 85
6 Implication of Reactive Oxygen Metabolites in Inflammatory Bowel Diseases 101
7 Interleukin-1, Neutrophils, and Oxidants in Acute Lung Injury 127
8 Free Radicals and Critical Care Medicine 141
9 Human Immunodeficiency Virus-1 Tat Protein and Oxidant/Antioxidant Balance 157
10 Myocardial Ischemia-Reperfusion Injury: Free Radicals 175
11 Oxidation of Low Density Lipoprotein in Plasma 219
12 Role of Reactive Oxygen Species in Multistage Carcinogenesis 237
Index 279
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