Oxygen Transport to Tissue XXVI / Edition 1

Oxygen Transport to Tissue XXVI / Edition 1

by Paul Okunieff
     
 

ISBN-10: 038725062X

ISBN-13: 9780387250625

Pub. Date: 11/01/2007

Publisher: Springer US

This book cover all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is

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Overview

This book cover all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.

Product Details

ISBN-13:
9780387250625
Publisher:
Springer US
Publication date:
11/01/2007
Series:
Advances in Experimental Medicine and Biology Series, #566
Edition description:
2005
Pages:
407
Product dimensions:
9.21(w) x 6.14(h) x 0.94(d)

Table of Contents

1Cerebral oxygenation during repetitive apnea in newborn piglets1
2Optimal determination of detector placement in cerebral NIR spectroscopy of neonates using chemometric techniques9
3Simulation study of breast tissue hemodynamics during pressure perturbation17
4Microvascular oxygenation and oxidative stress during postischemic reperfusion : PO[subscript 2], ROS, and NO during reperfusion23
5Hypoxia, tumor endothelium, and targets for therapy31
6Genetic oxygen sensor : GFP as an indicator of intracellular oxygenation39
7Effects of insulin and catecholamines on inotropy and oxygen uptake : best perfusate for skeletal muscles45
8Adaptation to chronic hypoxia during diet-induced ketosis51
9Varied response of spontaneous tumors to antiangiogenic agents59
10Non-invasive measurement of tumor oxygenation using embedded microparticulate EPR spin probe67
11The effects of tumour blood flow and oxygenation modifiers on subcutaneous tumours as determined by NIRS75
12Hyperthermia and hypermetabolism in focal cerebral ischemia83
13Variability of cerebral hemoglobin concentration in very preterm infants during the first 6 hours of life
14Computational study on use of single-point analysis method for quantitating local cerebral blood flow in mice99
15Effects of temperature on oxygen transport in sheets and spheres of respiring tissues105
16Modeling of the response of PtO2 in rat brain to changes in physiological parameters111
17Black magic and EPR oximetry : from lab to initial clinical trials
18Axial oxygen diffusion in the krogh model : modifications to account for myocardial oxygen tension in isolated perfused rat hearts measured by EPR oximetry127
19Differentiating hemodynamic compromise by the OEF response to acetazolamide in occlusive vascular disease
20The anomalous einstein-stokes behaviour of oxygen and other low molecular weight diffusants143
21Gut dysoxia : comparison of sites to detect regional gut dysoxia151
22Imaging oxygen pressure in the retina of the mouse eye159
23Fluorescence-mediated detection of a heterogeneity in a highly scattering media167
24Developing strategies for three-dimensional imaging of oxygen tension in the rodent retina173
25Cerebral PtO[subscript 2], acute hypoxia, and volatile anesthetics in the rat brain179
26Rate of change in cerebral oxygenation and blood pressure in response to passive changes in posture : a comparison between pure autonomic failure patients and controls
27Validation of the CAS neonatal NIRS system by monitoring VV-Ecmo patients : preliminary results
28Interactions between HIF-1 and Jab1 : balancing apoptosis and adaptation - outline of a working hypothesis203
29Past, present, and future of oxygen in cancer research213
30Benzoate hydroxylation : a measure of oxidative stress in divers223
31Mitochondrial NADH as the bellwether of tissue O[subscript 2] delivery231
32Process scale-up studies for protein C separation using IMAC243
33Hypoxia-induced alterations in hyaluronan and hyaluronidase
34Rate of decrease of PO[subscript 2] from an arteriole with arrested flow257
35Measurement of CMRO[subscript 2] in neonates undergoing intensive care using near infrared spectroscopy263
36The pathways of oxygen in brain I : delivery and metabolism of oxygen269
37The pathways of oxygen in brain II : competitions for cytochrome c oxidase and NOS are keys to flow-metabolism coupling277
38Exogenous and endogenous markers of tumour oxygenation status : definitive markers of tumour hypoxia?285
39The difficulties in comparing in vivo oxygen measurements : turning the problems into virtues295
40Preliminary study of simultaneous multi-anticoagulant deficiency diagnosis by fiber optic multi-analyte biosensor303
41Circulation time in man from lung to periphery as an indirect index of cardiac output
42Factors controlling oxygen utilization317
43Amputation level viability in critical Limb Ischaemia : setting new standards325
44Hypoxia in breast cancer : role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion333
45Monitoring metabolite gradients in the blood, liver, and tumor after induced hyperglycemia in rats with R3230 flank tumors using microdialysis and bioluminescence imaging343
46Possible protective effects of [alpha]-tocopherol on enhanced induction of reactive oxygen species by 2-methoxyestradiol in tumors349
47Simultaneous NIR-EPR spectroscopy of rat brain oxygenation357
48Microcirculation and reperfusion injury in organ transplantation363
49Focussing on genomic and phenomic correlations in respiration of non-melanotic skin cancers375
50Protein C production : metal ion/protein interfacial interaction in immobilized metal affinity chromatography381
51Modeling behavior of protein C during and after subcutaneous administration389
52Mechanisms for vasoconstriction and decreased blood flow following intravenous administration of cell-free native hemoglobin solutions397

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