Paediatric Nephrology / Edition 2

Paediatric Nephrology / Edition 2

by Lesley Rees, Paul A. Brogan, Detlef Bockenhauer, Nicholas J.A. Webb

ISBN-10: 0199601372

ISBN-13: 9780199601370

Pub. Date: 09/07/2012

Publisher: Oxford University Press, USA

Paediatric Nephrology is designed to help the reader understand and manage any condition affecting the kidney in childhood. It is pocket-sized to give easy reference in the clinical setting and highlights the important issues for quick use. From history taking and urinalysis, to acute renal failure, transplantation and actute kidney injury, all aspects are covered

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Paediatric Nephrology is designed to help the reader understand and manage any condition affecting the kidney in childhood. It is pocket-sized to give easy reference in the clinical setting and highlights the important issues for quick use. From history taking and urinalysis, to acute renal failure, transplantation and actute kidney injury, all aspects are covered in this concise yet comprehensive guide to this specialist area. It is an invaluable reference to the general paediatrician. The appendix provides useful additional information and protocols. This new edition is up-to-date and evidence-based, and tables and equations direct readers to correct drug dosages and use of relevant medication. Features:
• Covers common and rare conditions affecting the kidney in childhood
• Presented in easily accessible handbook format
• Key issues are highlighted wth bullet points and boxes
• Includes appendices and links to current literature and recommended drug dosages
• Includes colour plates for renal biopsy histopathology

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Product Details

Oxford University Press, USA
Publication date:
Product dimensions:
7.00(w) x 3.90(h) x 0.80(d)

Related Subjects

Table of Contents

Patient assessment
History and examination Abnormalities of the urine and urinalysis The approach to the child with haematuria The approach to the child with proteinuria Radiological investigations Recommendations for ultrasound screening for renal abnormalities Fluid and electrolyte abnormalities Percutaneous renal biopsy Genetic testing and antenatal diagnosis
The neonate
The foetus and birth Perinatal 'bright' kidneys Neonatal disorders of fluid balance Neonatal renal venous thrombosis
Congenital abnormalities
Antenatal diagnosis of structural renal abnormalities Renal agenesis Horseshoe kidney, renal ectopia and duplex kidneys The multicystic dysplastic kidney (MCDK)
Pelvi-ureteric junction (PUJ) abnormalities Megaureter Posterior urethral valves Urogenital sinus and cloacal abnormalities Absent abdominal musculature syndrome
Urinary tract infection
Background and clinical features Collection of urine samples and diagnosis Bacterial and host factors that predispose to infection Management Investigations The penis and foreskin Vulvovaginitis
Nocturnal enuresis Primary diurnal and secondary enuresis Bladder pathology
Disorders of sodium and water: Basic principles Disorders of sodium and water: Hypernatraemia Disorders of sodium and water: Hyponatraemia Disorders of potassium: Basic principles Disorders of potassium: Hyperkalaemia Disorders of potassium: Hypokalaemia Disorders of calcium: Basic principles Disorders of calcium: Hypercalcaemia Disorders of calcium: Hypocalcaemia Disorders of magnesium: Basic principles Disorders of magnesium:Hypermagnesaemia Disorders of magnesium: Hypomagnesaemia Disorders of phosphate: Basic principles Disorders of phosphate: Hyperphosphataemia Disorders of phosphate: Hypophosphataemia Disorders of acid-base balance: Basic principles Disorders of acid-base balance: Acidosis Disorders of acid-base balance: Alkalosis
Tubular disease
Disorders of renal salt handling: Basic principles Disorders of renal salt handling: Proximal tubule Disorders of renal salt handling: Thick ascending limb Disorders of renal salt handling: Distal convoluted tubule Disorders of renal salt handling: Collecting duct Disorders of renal water handling Disorders of renal magnesium handling Rickets Tubulointerstitial nephritis (TIN)
Renal calculi and nephrocalcinosis
Renal calculi Specific causes of calculi, their investigation and management Nephrocalcinosis
Glomerular disease
Overview of inherited glomerular diseases Alport syndrome and thin basement membrane nephropathy Acute nephritis IgA Nephropathy (IgAN)
Nephrotic syndromes: Definitions Congenital and Infantile Nephrotic Syndrome Steroid sensitive nephrotic syndrome: Presenting episode Steroid sensitive nephrotic syndrome: Relapsing disease Steroid resistant nephrotic syndrome (SRNS)
Systemic disease affecting the kidney
Systemic lupus erythematosus: Background, clinical evaluation and investigation Systemic lupus erythematosus: Treatment of non-renal SLE Systemic lupus erythematosus: Classification and treatment of lupus nephritis Systemic lupus erythematosus: B cell-targeted therapies Diabetes and metabolic syndrome Sickle cell disease Renal involvement in cystic fibrosis Sarcoidosis Mitochondrial cytopathies Fabry disease Amyloidosis The emergency renal management of inborn errors of metabolism (IEMs)
The classification of paediatric vasculitis Investigation of primary systemic vasculitis The standard treatment of childhood vasculitis Henoch Schonlein purpura Kawasaki disease Polyarteritis nodosa (PAN)
The anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides Takayasu arteritis
Infections and the kidney
Infections and the kidney
Renal cystic diseases and ciliopathies
Renal cystic diseases: Basic principles Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Renal structural abnormalities in Tuberous sclerosis Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Nephronophthisis (NPHP)
Renal cysts and diabetes syndrome Renal dysplasia
Syndromes associated with renal diseases
Overviews of genetrics and renal abnormalities in inherited syndromes Down syndrome Williams syndrome Branchio-oto-renal syndrome
Renal tumours
Wilms' tumour Other renal tumours
Basic concepts of blood pressure, and defining hypertension in children Measurement of blood pressure in infants and children The investigation of hypertension in the young Renovascular hypertension Treatment Ambulatory blood pressure measurement in children
Acute kidney injury
Background, pathophysiology and causes Assessment and investigations Management Hypertension Nutrition in AKI Drug therapy Dialysis Follow up of AKI Haemolytic uraemic syndrome (HUS): Definitions Typical (D+) HUS: Epidemiology and notes HUS: Atypical Rhabdomyolysis Tumour lysis syndrome
Chronic kidney disease
Background and epidemiology Assessment of renal function Investigation of the cause of CKD Management: Overall aims Management: Fluid and electrolytes Management: Growth Management: Nutrition Management: Use of recombinant human growth hormone (rhGH)
Management: Enteral feeding Management: Mineral and Bone Disorder (CKD-MBD)
Management: Anaemia Management: Immunisation schedule for infants and children Preparation for renal replacement therapy
Chronic peritoneal dialysis
Principles of peritoneal dialysis Peritoneal dialysis solutions Peritoneal equilibrium test (PET)
Peritonitis in patients on chronic peritoneal dialysis Sclerosing peritonitis
Extracorporeal treatments
Haemodialysis: Principles of haemodialysis Haemodialysis: The machine, dialysate and water Haemodialysis: Factors affecting the prescription Haemodialysis: Complications Haemodialysis: Adequacy Haemodialysis: Vascular access Haemodialysis: Blood-borne viruses Continuous renal replacement therapy (CRRT)
Plasmapheresis and immunoadsorption
Renal transplantation immunology Vaccination after transplantation Kidney transplantation-the surgery Immunosuppressive therapy in renal transplant patients Diagnosis and treatment of transplant rejection Recurrent and de novo renal disease following renal transplantation Urinary tract infection post transplantation New onset diabetes after transplantation Infection post transplant Malignancy following renal transplantation Graft survival in transplant recipients
Drug prescribing
Basic principles Specific drug issues of importance Intraperitoneal drug doses
Psychosocial issues
Ethical issues Non-adherence in paediatric renal disease Long-term growth Long term survival of children on renal replacement therapy Palliative care
Assessment of glomerular filtration rate (GFR)
Furosemide test of urinary acidification DDAVP test Disodium pamidronate infusion Intravenous cyclophosphamide Guidelines for the use of Basiliximab (Simulect)
Protocol for administration of blood to patients with or approaching CKD 5
Protocol for percutaneous transluminal angioplasty Travel information - Guidance for renal patients Guidelines for the treatment of swine flu (H1N1) infection in children with renal disease Miscellaneous

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