Paediatric Nephrology / Edition 2

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Paediatric Nephrology is designed to help the reader understand and manage any condition affecting the kidney in childhood. It is pocket-sized to give easy reference in the clinical setting and highlights the important issues for quick use. From history taking and urinalysis, to acute renal failure, transplantation and actute kidney injury, all aspects are covered in this concise yet comprehensive guide to this specialist area. It is an invaluable reference to the general paediatrician. The appendix provides useful additional information and protocols. This new edition is up-to-date and evidence-based, and tables and equations direct readers to correct drug dosages and use of relevant medication. Features:
• Covers common and rare conditions affecting the kidney in childhood
• Presented in easily accessible handbook format
• Key issues are highlighted wth bullet points and boxes
• Includes appendices and links to current literature and recommended drug dosages
• Includes colour plates for renal biopsy histopathology

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Editorial Reviews

Doody's Review Service
Reviewer: Stefan G Kiessling, MD (University of Kentucky College of Medicine)
Description: Part of the Oxford Specialist Handbooks in Paediatrics series, this is an update of an information-rich, accessible pocket reference that covers all major clinical aspects of pediatric nephrology. The book is authored by four European experts in the field with an equally expert advisory group. Numerous figures and tables are well integrated into 23 structured chapters. As the only pocket reference in the field, the book was long needed before the first edition was published in 2007 and is even stronger in this current version. A must-have for anyone involved in the care of children.
Purpose: With this second edition, the handbook continues to function as a comprehensive quick reference, essentially covering all clinical aspects of normal and abnormal kidney function as well as diagnostic evaluation and treatment of clinical conditions in pediatric nephrology. Recruitment of Dr. Detlef Bockenhauer, an internationally known senior pediatric nephrologist as an editor makes the publication even stronger. Different from other publications in this particular field (and therefore filling a long existing gap), this book provides a predominantly clinical approach to each topic without getting lost in too much detail that interested readers can find in standard textbooks.
Audience: Given its concise but comprehensive structure - each chapter covers a broad topic in the field of pediatric nephrology — it is a great resource for clinicians at any level, ranging from students and trainees to senior pediatricians and specialists in the field.
Features: Each of the 23 chapters starts with a general outline and is divided into subsections as necessary. The typesetting, font, and overall outline of each chapter make it extremely easy for readers to access and review information. All essential and clinically relevant topics in the field of pediatric nephrology are covered, including a section on nephrological conditions of the newborn as well as renal replacement therapies and kidney transplantation. A minor disadvantage might be the limited number of references.
Assessment: This handbook successfully accomplishes its goals. It is a unique publication that truly does not have a comparable equivalent. Pediatric Nephrology for Primary Care, Barakat and Chesney (American Academy of Pediatrics, 2009), is also in handbook format, but targets general pediatricians. This book certainly does not replace or try to replace major textbooks in the field (Pediatric Nephrology, 6th edition, Avner et al. (Springer, 2009); Comprehensive Pediatric Nephrology, Geary and Schaefer (Elsevier, 2008)), but it is an extremely useful resource in its new edition. It will be widely used by clinicians at all levels.
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Product Details

  • ISBN-13: 9780199601370
  • Publisher: Oxford University Press, USA
  • Publication date: 9/7/2012
  • Edition number: 2
  • Pages: 656
  • Product dimensions: 7.00 (w) x 3.90 (h) x 0.80 (d)

Table of Contents

Patient assessment
History and examination Abnormalities of the urine and urinalysis The approach to the child with haematuria The approach to the child with proteinuria Radiological investigations Recommendations for ultrasound screening for renal abnormalities Fluid and electrolyte abnormalities Percutaneous renal biopsy Genetic testing and antenatal diagnosis
The neonate
The foetus and birth Perinatal 'bright' kidneys Neonatal disorders of fluid balance Neonatal renal venous thrombosis
Congenital abnormalities
Antenatal diagnosis of structural renal abnormalities Renal agenesis Horseshoe kidney, renal ectopia and duplex kidneys The multicystic dysplastic kidney (MCDK)
Pelvi-ureteric junction (PUJ) abnormalities Megaureter Posterior urethral valves Urogenital sinus and cloacal abnormalities Absent abdominal musculature syndrome
Urinary tract infection
Background and clinical features Collection of urine samples and diagnosis Bacterial and host factors that predispose to infection Management Investigations The penis and foreskin Vulvovaginitis
Nocturnal enuresis Primary diurnal and secondary enuresis Bladder pathology
Disorders of sodium and water: Basic principles Disorders of sodium and water: Hypernatraemia Disorders of sodium and water: Hyponatraemia Disorders of potassium: Basic principles Disorders of potassium: Hyperkalaemia Disorders of potassium: Hypokalaemia Disorders of calcium: Basic principles Disorders of calcium: Hypercalcaemia Disorders of calcium: Hypocalcaemia Disorders of magnesium: Basic principles Disorders of magnesium:Hypermagnesaemia Disorders of magnesium: Hypomagnesaemia Disorders of phosphate: Basic principles Disorders of phosphate: Hyperphosphataemia Disorders of phosphate: Hypophosphataemia Disorders of acid-base balance: Basic principles Disorders of acid-base balance: Acidosis Disorders of acid-base balance: Alkalosis
Tubular disease
Disorders of renal salt handling: Basic principles Disorders of renal salt handling: Proximal tubule Disorders of renal salt handling: Thick ascending limb Disorders of renal salt handling: Distal convoluted tubule Disorders of renal salt handling: Collecting duct Disorders of renal water handling Disorders of renal magnesium handling Rickets Tubulointerstitial nephritis (TIN)
Renal calculi and nephrocalcinosis
Renal calculi Specific causes of calculi, their investigation and management Nephrocalcinosis
Glomerular disease
Overview of inherited glomerular diseases Alport syndrome and thin basement membrane nephropathy Acute nephritis IgA Nephropathy (IgAN)
Nephrotic syndromes: Definitions Congenital and Infantile Nephrotic Syndrome Steroid sensitive nephrotic syndrome: Presenting episode Steroid sensitive nephrotic syndrome: Relapsing disease Steroid resistant nephrotic syndrome (SRNS)
Systemic disease affecting the kidney
Systemic lupus erythematosus: Background, clinical evaluation and investigation Systemic lupus erythematosus: Treatment of non-renal SLE Systemic lupus erythematosus: Classification and treatment of lupus nephritis Systemic lupus erythematosus: B cell-targeted therapies Diabetes and metabolic syndrome Sickle cell disease Renal involvement in cystic fibrosis Sarcoidosis Mitochondrial cytopathies Fabry disease Amyloidosis The emergency renal management of inborn errors of metabolism (IEMs)
The classification of paediatric vasculitis Investigation of primary systemic vasculitis The standard treatment of childhood vasculitis Henoch Schonlein purpura Kawasaki disease Polyarteritis nodosa (PAN)
The anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides Takayasu arteritis
Infections and the kidney
Infections and the kidney
Renal cystic diseases and ciliopathies
Renal cystic diseases: Basic principles Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Renal structural abnormalities in Tuberous sclerosis Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Nephronophthisis (NPHP)
Renal cysts and diabetes syndrome Renal dysplasia
Syndromes associated with renal diseases
Overviews of genetrics and renal abnormalities in inherited syndromes Down syndrome Williams syndrome Branchio-oto-renal syndrome
Renal tumours
Wilms' tumour Other renal tumours
Basic concepts of blood pressure, and defining hypertension in children Measurement of blood pressure in infants and children The investigation of hypertension in the young Renovascular hypertension Treatment Ambulatory blood pressure measurement in children
Acute kidney injury
Background, pathophysiology and causes Assessment and investigations Management Hypertension Nutrition in AKI Drug therapy Dialysis Follow up of AKI Haemolytic uraemic syndrome (HUS): Definitions Typical (D+) HUS: Epidemiology and notes HUS: Atypical Rhabdomyolysis Tumour lysis syndrome
Chronic kidney disease
Background and epidemiology Assessment of renal function Investigation of the cause of CKD Management: Overall aims Management: Fluid and electrolytes Management: Growth Management: Nutrition Management: Use of recombinant human growth hormone (rhGH)
Management: Enteral feeding Management: Mineral and Bone Disorder (CKD-MBD)
Management: Anaemia Management: Immunisation schedule for infants and children Preparation for renal replacement therapy
Chronic peritoneal dialysis
Principles of peritoneal dialysis Peritoneal dialysis solutions Peritoneal equilibrium test (PET)
Peritonitis in patients on chronic peritoneal dialysis Sclerosing peritonitis
Extracorporeal treatments
Haemodialysis: Principles of haemodialysis Haemodialysis: The machine, dialysate and water Haemodialysis: Factors affecting the prescription Haemodialysis: Complications Haemodialysis: Adequacy Haemodialysis: Vascular access Haemodialysis: Blood-borne viruses Continuous renal replacement therapy (CRRT)
Plasmapheresis and immunoadsorption
Renal transplantation immunology Vaccination after transplantation Kidney transplantation-the surgery Immunosuppressive therapy in renal transplant patients Diagnosis and treatment of transplant rejection Recurrent and de novo renal disease following renal transplantation Urinary tract infection post transplantation New onset diabetes after transplantation Infection post transplant Malignancy following renal transplantation Graft survival in transplant recipients
Drug prescribing
Basic principles Specific drug issues of importance Intraperitoneal drug doses
Psychosocial issues
Ethical issues Non-adherence in paediatric renal disease Long-term growth Long term survival of children on renal replacement therapy Palliative care
Assessment of glomerular filtration rate (GFR)
Furosemide test of urinary acidification DDAVP test Disodium pamidronate infusion Intravenous cyclophosphamide Guidelines for the use of Basiliximab (Simulect)
Protocol for administration of blood to patients with or approaching CKD 5
Protocol for percutaneous transluminal angioplasty Travel information - Guidance for renal patients Guidelines for the treatment of swine flu (H1N1) infection in children with renal disease Miscellaneous

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