Paediatrics and Blood Transfusion: Proceedings of the Fifth Annual Symposium on Blood Transfusion, Groningen 1980 organized by the Red Cross Bloodbank Groningen-Drenthe / Edition 1

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Table of Contents

I. Historical perspectives of Haemolytic Disease of the Newborn.- I. Historical perspectives of Haemolytic Disease of the Newborn.- II. Pathogenetic aspects.- 1. The serological investigation of Haemolytic Disease of the Newborn.- 2. The laboratory investigation of ABO Haemolytic Disease of the Newborn and dangers arising from the transfusion of group O donorblood containing AB bloodgroup substance of animal origin.- 3. Haemolytic Disease: clinical diagnosis.- 4. Discussion.- III. Preventative aspects.- 1. The supply of anti-Rhesus (D) immunoglobulin in the Netherlands.- 2. Anti-Rhesus (D) immunoglobulin: indications, clinical use and effect on incidence of Haemolytic Disease of the Newborn.- 3. Discussion.- IV. Therapeutic aspects.- A. Metabolic aspects.- 1. Haemolytic Disease of the Newborn: an overview of the principles of therapy.- 2. The use of component therapy in the newborn.- 3. Metabolic effects of exchange transfusion.- 4. Exchange transfusion: metabolic aspects and biochemical changes.- 5. Discussion.- B. Practical aspects.- 1. Paediatrics and bloodtransfusion: practical aspects.- 2. Practical aspects of exchange transfusion.- 3. Indications for exchange transfusion and choice of treatment for Haemolytic Disease of the Newborn.- 4. Progress in exchange transfusion techniques.- 5. Practical experience in neonatal exchange transfusion.- 6. Exchange transfusion in the Netherlands: a personal view.- 7. Discussion.- C. Special Techniques.- 1. Use of infusion pumps for paediatric blood transfusion.- 2. Prevention of severe Haemolytic Disease of the Newborn by weekly small-volume plasmapheresis during pregnancy.- 3. Intra-uterine fetal transfusion in severe Rh-iso immunisation.- 4. Development of infants surviving intrauterine transfusion.- 5. Discussion.- D. Risks of transmitting disease.- 1. Cytomegalovirus infections.- 2. Serodiagnosis and control in viral hepatitis.- 3. Discussion.- V. Intensive care of the neonate.- 1. Some aspects of neonatal thrombocytopenia.- 2. Cytapheresis support in childhood oncology.- 3. Platelet transfusion in bone marrow transplantation in children.- 4. Discussion.- VI. Concluding remarks.- VI. Concluding remarks.

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