Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment

Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment

by James P Knaak
     
 


The metabolism of modern agrochemicals in animals, plants, and the environment have been extensively studied and reported in the literature by scientists. The results of a considerable number of these studies have been presented at National ACS, AGRO Division meetings and eventually published in the Journal of Agricultural and Food Chemistry, the ACS Symposium… See more details below

Overview


The metabolism of modern agrochemicals in animals, plants, and the environment have been extensively studied and reported in the literature by scientists. The results of a considerable number of these studies have been presented at National ACS, AGRO Division meetings and eventually published in the Journal of Agricultural and Food Chemistry, the ACS Symposium Series, as well as other ACS journals and books. These studies support the current registrations and use of pesticides in the United States and worldwide. The integration of metabolism and toxicological studies in assessing human risks to pesticides is best performed using predictive physiological pharmacokinetic/pharmacodynamic and QSAR models. Physiological, biochemical, and toxicological parameters are required for model development and is the subject of the chapters in this book. The book will update the scientific community in the development of the parameters required by pesticide PBPK/PD models and their application in model development, simulation, and risk assessment.

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Product Details

ISBN-13:
9780841226456
Publisher:
American Chemical Society
Publication date:
08/28/2012
Series:
ACS Symposium Series, #1099
Pages:
368
Product dimensions:
6.10(w) x 9.00(h) x 0.90(d)

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