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From The CriticsReviewer: Karen Sterling SantaCruz, MD(University of Kansas School of Medicine)
Description: This book presents information on the histology, histochemistry, and electron microscopy of muscle biopsy specimens in a manner that is useful both for diagnosis and as a reference source. Recent advances regarding genetic defects as the cause of muscle diseases is included and there are numerous photographs of histologic sections, resin embedded material, and electron microscopy. This is an updated version of the book originally published in 1986.
Purpose: The purpose is to provide an accurate description of a variety of specific and nonspecific changes seen in diseased muscle. This is a worthy objective and the book succeeds in providing a well organized, up-to-date source that is useful in educating residents as well as assisting neuropathologists and other diagnosticians in their quest to provide useful information to clinicians caring for patients with muscle disease.
Audience: Although this book is probably most useful to neuropathologists and other diagnosticians who sign out muscle biopsies on a regular basis, it is also useful to introduce concepts of muscle pathology to residents and clinicians to muscle biopsy pathology. The authors are recognized as world experts in muscle pathology and they have signed out over 2,000 muscles during their more than 28 years of combined experience.
Features: This book describes general pathologic reactions of skeletal muscle and specific and nonspecific changes associated with a wide variety of disease processes. It is organized primarily by diagnosis so that pathologists can compare descriptions of classic cases to their current surgical material. Resin embedded and electron microscopic photographs are heavily relied upon to describe common changes seen with specific disease processes. Very few color images or images of special stains, immunohistochemistry, or standard H&E sections are included although there are frequent references to what would be seen with these techniques.
Assessment: This is an authoritative and well illustrated muscle pathology reference that is easier to navigate than other, similar sources. The emphasis on practical descriptions and the de-emphasis of clinical descriptions and research models makes this book easier to use than similar books that contain more detailed descriptions of pathogenic mechanisms and clinical correlation. The new edition contains well organized tables on recent advances in the understanding of the role of surface membrane proteins in human disease.