Pathology of the Human Placenta

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This third edition has been written because of the many new findings and the ever-growing need to have documentation for legal purposes; moreover, organization of the second edition left some aspects uncovered.

The book contains black-and-white illustrations.

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Overview

This third edition has been written because of the many new findings and the ever-growing need to have documentation for legal purposes; moreover, organization of the second edition left some aspects uncovered.

The book contains black-and-white illustrations.

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Editorial Reviews

From The Critics
Reviewer:Ivan Damjanov, MD(University of Kansas Medical Center)
Description:This is the fifth edition of the leading textbook of placental pathology, which was first published 40 years ago. It is also the only book that deals in detail with normal placenta. The authors have significantly updated the previous edition of 2000 and have expanded the book, which now contains both black-and-white and color photographs.
Purpose:The original text was prepared in 1967 as part of the famous German encyclopedia series edited by Henke and Lubarsch. As such, it was designed to be encyclopedic and include all that was known at that time about the pathology of placenta. Ever since, Dr. Benirschke, now joined by two coauthors, has continued updating the original, which has grown in size and breadth of coverage over the years. This edition is an excellent update and thus remains the most complete textbook of normal and abnormal placentology currently available on the market.
Audience:Aimed at pathologists and neonatologists, this book will be used by scientifically minded gynecologists and neonatologists and all other scientists interested in prenatal growth and development of the human fetus and fetal membranes. It is also a "must have" for all lawyers involved in malpractice cases relating to the prenatal and early postnatal period of life.
Features:This is a massive large format book, over 1,000 pages, printed on high quality paper. Approximately one-third of the book is devoted to normal human placentation, placental physiology, metabolism, and endocrinology. The remaining two-thirds deal with placental pathology. Almost all placental diseases are covered in great detail, including shape aberrations of the placenta, villous abnormalities, infectious diseases, etc. Special chapters are dedicated to maternal diseases complicating pregnancy, erythroblatosis fetalis, transplacental hemorrhages and cell transfer, and trauma. Abortions and related fetal abnormalities are also covered. A considerable number of pages are devoted to molar pregnancies and trophoblastic tumors. An informative chapter deals with multiple pregnancies. A short but important chapter covers legal considerations. The book is illustrated with 745 excellent black-and-white illustrations, including numerous outstanding electron microphotographs. Unfortunately, the 170 color photos are of uneven quality and are often inferior to the black-and-white illustrations. The references are current and well chosen.
Assessment:This is unquestionably the most encyclopedic book on normal and abnormal placentation. The latest edition is as good as the previous editions, on which it has built its strength and whose format it has retained. This update, coming six years after the previous edition, is fully justified. As such, this book has no competition and remains the most preeminent and most comprehensive book in this field.
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Product Details

  • ISBN-13: 9780387972824
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 4/1/1992
  • Edition description: 2nd ed
  • Edition number: 2
  • Pages: 878

Meet the Author

Kurt Benirschke received his MD from the University of Hamburg in 1948 and subsequently moved to the United States, where he trained in pathology at different university hospitals. He held various Harvard Medical School appointments before becoming Professor of Pathology and Chairman of the Department of Pathology at Dartmouth Medical School in Hanover, New Hampshire, where his interests included placental pathology, comparative reproductive pathology, and comparative cytogenetics. In 1970, Dr. Benirschke became Professor of Pathology and Reproductive Medicine at the University of California, San Diego Medical Center. He established a genetics laboratory and ran the autopsy service at the Center, and also chaired the Department of Pathology for 2 years. In addition, he served as Director of Research at San Diego Zoo in a newly established research department. There, he established the first “frozen zoo,” comprising a collection of frozen cells and reproductive material from highly endangered species. Dr. Benirschke was elected a Fellow of the American Academy of Arts and Sciences in 1994. After retiring from the faculty at UCSD he was appointed Professor Emeritus and also served as President of the Zoo's Board of Trustees. His many honors and awards include the ARCS Foundation Scientist of the Year in 1997, the Association of Zoos and Aquariums’ R. Marlin Perkins Award in 1998, and the E.A. Dickson Emeriti Professorship in 2008. Dr. Benirschke has served on a number of journal editorial boards and has authored 544 scientific papers, 111 book chapters, and 31 books.
Graham J. Burton gained a BA in Medical Sciences Tripos at Cambridge University before obtaining a BM BCh degree in Clinical Medicine at Oxford University. In 1982 he was appointed University Lecturer in the Department of Anatomy, and he acquired his MD in 1984. He went on to become Director of Studies in Pre-clinical Medical Studies at St. John’s College, Director of the Sub-department of Veterinary Anatomy, Tutor of St. John’s College, and University Reader in Human Reproduction in the Department of Anatomy. In 2004 he was appointed Professor of Reproductive Biology at the University of Cambridge, and he is currently Deputy Head of the Department of Physiology, Development and Neuroscience and Director of the Centre for Trophoblast Research at the University. Since 2008 Dr. Burton has been European Editor of Placenta and he is also a member of the Editorial Board of the Journal of Anatomy and the Board of Reviewing Editors for Biology of Reproduction. He has been a member of various committees for the International Federation of Placental Associations. Dr. Burton has received several awards, including the 2005 FEDERA Award from the Dutch Federation of Medical Scientific Societies. He was elected an FMedSci in 2011. Dr. Burton has published more than 150 articles in refereed journals as well as many book chapters and two books.
Rebecca Baergen obtained her MD from the University of California, Los Angeles, School of Medicine in 1983 and completed her residency training in pathology at the Los Angeles County Harbor-UCLA Medical Center. Dr. Baergen was a member of the faculty of the University of California at San Diego until transferring to the Weill Medical College of Cornell University in 1997. Dr. Baergen trained with Dr. Kurt Benirschke, one of the pioneers in placental and perinatal pathology and co-author of this book. Dr. Baergen is now Professor of Clinical Pathology and Laboratory Medicine and Chief of Perinatal and Pediatric Pathology at Weill Medical College, as well as Attending Pathologist at NewYork-Presbyterian Hospital. Dr. Baergen has lectured and published extensively in this field and her special interests include the pathogenesis of fetal demise, fetal growth restriction, placental malperfusion, maternal thrombophilias, fetal vascular thrombosis, and abnormalities of the umbilical cord. She has authored approximately 70 publications in peer-reviewed journals.
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Table of Contents

1 Examination of the placenta 1
2 Macroscopic features of the delivered placenta 13
3 Microscopic survey 16
4 Placental types 30
5 Early development of the human placenta 42
6 Basic structure of the villous trees 50
7 Architecture of normal villous trees 121
8 Characterization of the development stages 174
9 Nonvillous parts and trophoblast invasion 191
10 Involution of placental site; retained placenta 313
11 Anatomy and pathology of the placental membranes 321
12 Anatomy and pathology of the umbilical cord 380
13 Placental shape aberrations 452
14 Histopathologic approach to villous alterations 473
15 Classification of villous maldevelopment 491
16 Erythroblastosis fetalis and hydrops fetalis 519
17 Transplacental haemorrhage, cell transfer, trauma 552
18 Fetal storage disorders 577
19 Maternal diseases complicating pregnancy : diabetes, tumors, preeclampsia, lupus anticoagulant 584
20 Infectious diseases 657
21 Abortion, placentas of trisomies, and immunologic considerations of recurrent reproductive failure 762
22 Molar pregnancies 797
23 Trophoblastic neoplasms 837
24 Benign tumors and chorangiosis 863
25 Multiple pregnancies 877
26 Legal considerations 1001
27 Glossary 1016
28 Normative values and tables 1019
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