Pathophysiology: The Biologic Basis for Disease in Adults and Children / Edition 6

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Overview

Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, this textbook features expert content on everything from the general principles of pathophysiology to detailed discussions of genetics and specific diseases. Chapters on alteration present the pathophysiology, clinical manifestations, and evaluation and treatment of each disease to help you learn to identify normal anatomy and physiology, as well as alterations of function in adults and in children.

• Unparalleled coverage of disease processes makes this text the most comprehensive pathophysiology text available.
• The largest full-color art program in the field illustrates the clinical manifestations of diseases and disease processes
• Consistent presentations of each disease with pathophysiology, clinical manifestations, and evaluation and treatment help you find the information you need quickly and easily.
• Ten separate pediatric chapters cover the pathophysiologic effects on children.
• Aging content is highlighted throughout the text.
• An Introduction to Pathophysiology section at the beginning of the text provides a solid start to the basics of the study of disease.
• Algorithms and flowcharts of diseases and disorders illustrate the disease process in an easy-to-understand format.
• Nutrition and Disease boxes present evidence-based information on the relationship between health promotion through diet and disease.

• Updated content on leukocytes in pain modulation, seizure disorders, brain injuries and disorders, acute encephalopathies, reproductive disorders, and much more keep you at the cutting edge of this constantly changing field.
• What’s New? boxes highlight the most current research and findings to ensure you have the most up-to-date information.
• New animations, review questions, Key Points, and an audio glossary have been added to the Evolve companion website to strengthen your understanding of key concepts.
• Media Resources Lists encourage you to develop a study plan to master the important content in each chapter.

The book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews


Reviewer: Kevin J Watson, BA, RRT(William Beaumont Hospitals)
Description: This sixth edition of a pathophysiology textbook includes more than 300 new full-color illustrations and photographs as well as major revisions, updated content, and reorganized data in many of the chapters. New information is provided on esophagitis and esophageal reflux, inherited disorders of the renal system, neuroregulation of hormone responses and hormonal immune system interaction, pain modulation, chronic pain syndromes, and classification of sleep disorders.
Purpose: The authors explore the ways in which the various cells, tissues, and organs suffer within the human body, providing a comprehensive overview of pathophysiology. The authors hope readers will realize that the conceptual models used in the book relate not only to the suffering of cells, tissues, and organ systems but also of human beings — there is a person on the receiving end of all that suffering or pathology. The revisions in this edition make it a valuable and comprehensive resource.
Audience: Although not specifically stated, the book is designed for college-level healthcare programs, but anyone interested in the pathophysiology of the human body would benefit from reading this well-written and logically organized book.
Features: The book is organized into two parts. Part one covers the central concepts of pathophysiology of cells and tissues or the cellular environment. The 13 chapters in this part cover cellular biology, altered cellular and tissue biology, the cellular environment, genes and genetic diseases, immunity, infection and cancer. Part two deals with the suffering or pathophysiology within each organ system and the interaction that can occur with multiple organ system failure. Each organ system is easily identifiable by the index color coding at the top of the fore edge of the page. There are 11 units in this part, made up of chapters 14-46. Each organ system discussion includes the male and female anatomy of the system if there are differences, alterations in those systems, and alterations specific for children. The book includes numerous full color artist conceptions, color and black-and-white photographs, tables, figures, a 22-page glossary and hypertext links to online resources. The online resource provides a more comprehensive glossary and multimedia content.
Assessment: This updated edition is well written and logically organized and can go toe-to-toe with any other pathophysiology textbook. This is an excellent choice for healthcare students and would provide a worthy resource for public, college, and university libraries as well.
Don Johnson
This third edition textbook is divided into two parts: central concepts related to cells and tissues, and pathophysiologic alterations. Part one gives an in-depth view of cells, genes and common genetic diseases, cell injury, fluid and electrolytes and acid-base balance, immunity, inflammation and wound healing, coping and illness, and oncogenesis. Part two gives a systematic survey of diseases within the systems that includes epidemiology, pathophysiology, clinical manifestations, and treatment modalities. The purpose is to provide an in-depth and current understanding of disease processes across the life span; to link relevant modern biology to a disease state; describe gender differences related to epidemiology and pathophysiology; and to integrate health promotion and disease prevention. Risk factors and nutrition are incorporated. The book is useful for practicing nurses and students in pathophysiology courses. The overall design is very logical. The first section provides a framework for understanding broad concepts such as genetics, cell injury, immunity, and inflammation. The second section examines normal anatomy and physiology, which serve as a basis for understanding common pathophysiology of adults and children. A new feature is "What's New Boxes," which present easy to understand updates in research. This textbook has always been an excellent resource and this new edition adds full color illustrations. There are algorithms that summarize important physiological and pathophysiological mechanisms. Students often indicate that these provide a quick means for review. Full-color photographs of clinical manifestations, specimens, and clinical imaging techniques add tothe text. Case studies are strategically included for each chapter dealing with disease states. New sections on headaches, neurobiology of selected psychiatric conditions, an integrated chapter on multiple interacting systems, and new illustrations make this text even better than previous editions.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780323065849
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/19/2009
  • Edition description: New Edition
  • Edition number: 6
  • Pages: 1838
  • Sales rank: 33720
  • Product dimensions: 8.90 (w) x 11.00 (h) x 2.40 (d)

Table of Contents

Introduction to Pathophysiology

PART ONE: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES

Unit I: The Cell

  1. Cellular Biology
  2. Altered Cellular and Tissue Biology
  3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases
  4. Unit II: Genes and Gene-Environment Interaction

  5. Genes and Genetic Diseases
  6. Genes, Environment, Life-style, and Common Diseases
  7. Unit III: Mechanisms of Self-Defense

  8. Innate Immunity: Inflammation
  9. Adaptive Immunity
  10. Alterations in Immunity and Inflammation
  11. Infection
  12. Stress and Disease
  13. Unit IV: Cellular Proliferation: Cancer

  14. Biology, Clinical Manifestations, and Treatment of Cancer
  15. Cancer Epidemiology
  16. Cancer in Children
  17. PART TWO: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS

    Unit V: The Neurologic System

  18. Structure and Function of the Neurologic System
  19. Pain, Temperature Regulation, Sleep, and Sensory Function
  20. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function
  21. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
  22. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders
  23. Alterations of Neurologic Function in Children
  24. Unit VI: The Endocrine System

  25. Mechanisms of Hormonal Regulation
  26. Alterations of Hormonal Regulation
  27. Unit VII: The Reproductive Systems

  28. Structure and Function of the Reproductive Systems
  29. Alterations of the Reproductive Systems
  30. Sexually Transmitted Infections
  31. Unit VIII: The Hematologic System

  32. Structure and Function of the Hematologic System
  33. Alterations of Erythrocyte Function
  34. Alterations of Leukocyte, Lymphoid, and Hemostatic Function
  35. Alterations of Hematologic Function in Children
  36. Unit IX: The Cardiovascular and Lymphatic Systems

  37. Structure and Function of the Cardiovascular and Lymphatic Systems
  38. Alterations of Cardiovascular Function
  39. Alterations of Cardiovascular Function in Children
  40. Unit X: The Pulmonary System

  41. Structure and Function of the Pulmonary System
  42. Alterations of Pulmonary Function
  43. Alterations of Pulmonary Function in Children
  44. Unit XI: The Renal and Urologic System

  45. Structure and Function of the Renal and Urologic Systems
  46. Alterations of Renal and Urinary Tract Function
  47. Alterations of Renal and Urinary Tract Function in Children
  48. Unit XII: The Digestive System

  49. Structure and Function of the Digestive System
  50. Alterations of Digestive Function
  51. Alterations of Digestive Function in Children
  52. Unit XIII: The Musculoskeletal System

  53. Structure and Function of the Musculoskeletal System
  54. Alterations of Musculoskeletal Function
  55. Alterations of Musculoskeletal Function in Children
  56. Unit XIV: The Integumentary System

  57. Structure, Function, and Disorders of the Integument
  58. Alterations of the Integument in Children
  59. Unit XV: Multiple Interacting Systems

  60. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
  61. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children
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Customer Reviews

Average Rating 3
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  • Posted Mon Dec 29 00:00:00 EST 2008

    more from this reviewer

    This book is NOT for beginning nursing students

    I have used this book in advanced practice preparation and practice. This book is for the individual with an intermediate background in pathophysiology and wants to know more. Nurses are life long learners and as you practice in your profession you will see things that you want to understand better so that you can critically think about what is going on with your clients. This book will help, DON'T throw the baby out with the bath water. Keep this book on your shelf until the thirst for knowledge needs to be quenched, then pick up this book and drink it all in.

    4 out of 4 people found this review helpful.

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  • Anonymous

    Posted Sun Jul 08 00:00:00 EDT 2007

    Reference book for non-beginners

    I have to agree with some previous reviewers that it's very detailed and 'difficult'. The book outlines pathophysiology to chemical, cellular levels which sometimes get very complex. But that's the essences of this book. This book is not for beginner to learn the pathophysiology. To fully appreciate the fine details the book puts out, the reader must have absolute solid understanding of basic (and bit of intermediate) pathophysiology in addition to basic physioloy and biology. This book is not for quick reference purpose. It takes time to comprehend the complexity, but the human body is complex, too. But once you 'get it' you'll appreciate the knowledge the book revealed. Considering how complex the human body is, the book did a fine job of 'dividing' the body into chapters. So it's no surprising to me that I have to flip back and forth between chapters to understand something as a whole. I have been using this book since it's 2nd edition. It has gone through a lot of improvements, believe me. My husband and I are both critical care RNs and we both love it. I highly recommend this book for non-beginners. It is excellent reference book.

    3 out of 3 people found this review helpful.

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  • Anonymous

    Posted Mon Feb 12 00:00:00 EST 2007

    Nurse

    Others that have rated this book poorly didn't have much nursing background. This book is not appropriate for the student who hasn't completed a year of nursing school. Otherwise it is an good reference book but not the one I turn to the most.

    2 out of 2 people found this review helpful.

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  • Anonymous

    Posted Sun Sep 03 00:00:00 EDT 2006

    Difficult to Comprehend

    I agree this is a bad text with important information buried in technical detail fit for a research scientist. I've never encountered another text this difficult to read. I have a degree in accounting and am taking this course as a prerequiste for a nursing program. There should have been prerequisites for this text.

    2 out of 2 people found this review helpful.

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  • Anonymous

    Posted Mon Jun 29 00:00:00 EDT 2009

    Great Book

    I bought this book because its the book suggessted for reference for my graudate study. I think its very good. I would recommend it for advance pathophysiology course but for basics Medical Surgical Books are still the best.

    1 out of 1 people found this review helpful.

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  • Anonymous

    Posted Sat Sep 23 00:00:00 EDT 2006

    This book is pathological

    Very poorly written and difficult to comprehend.

    1 out of 2 people found this review helpful.

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  • Anonymous

    Posted Sun Sep 30 00:00:00 EDT 2012

    Improved from prev edition but still disorganized.

    Currently using book to assist in teaching class; previously used last edition.
    I find this version addresses certain phrases with better explanations, but in some topics the order of introduction is suboptimal. Many times certain subjects are explained in clearer ways significantly later in the same chapter. Diagrams are often arranged poorly in relation to the text; sheer number of images on certain pages is distracting from being able to read a topic without stopping.

    Was this review helpful? Yes  No   Report this review
  • Anonymous

    Posted Sat Feb 20 00:00:00 EST 2010

    delivery

    The only problem was with the delivery time. This was for an online grad. level class. The delivery time was supposed to be 3 days. However, it took 7-8 days for the book to arrive. The first test was 2 days after the arrival.

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  • Posted Sat May 09 00:00:00 EDT 2009

    more from this reviewer

    Pathophysiology Masters Class

    I am currently taking advanced pathophysiology and I found this book to be a good source of basic information. But, since the book is published in 2006, it is lacking many new advancements in medicine. I find using current medical journals a much more accurate resource,

    Was this review helpful? Yes  No   Report this review
  • Anonymous

    Posted Fri Jun 16 00:00:00 EDT 2006

    The worst text book ever written

    Text is heavily populated with extensive details to the extent that the main idea on every subject is hard to find. I have to use other books in order to find clear explanations about pathophysiology. Quantity does not equal quality.

    Was this review helpful? Yes  No   Report this review
  • Anonymous

    Posted Sat Mar 04 00:00:00 EST 2000

    Want a great book on diseases? This is the best I have found!

    I am a nursing student and I bought this book for additional information on diseases. I find this book easier to read and better structured than the required text I have bought for my nursing classes. The pre and post chapter sections make this book easy to understand and complete!

    Was this review helpful? Yes  No   Report this review
  • Anonymous

    Posted Sat Dec 05 00:00:00 EST 2009

    No text was provided for this review.

  • Anonymous

    Posted Tue Nov 18 00:00:00 EST 2008

    No text was provided for this review.

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