Pathophysiology: The Biologic Basis for Disease in Adults and Children / Edition 4

Pathophysiology: The Biologic Basis for Disease in Adults and Children / Edition 4

3.0 14
by Kathryn L. McCance

ISBN-10: 0323014380

ISBN-13: 9780323014380

Pub. Date: 11/28/2001

Publisher: Elsevier Health Sciences

Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, the 5th edition of this classic book has been extensively revised and updated. Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role

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Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, the 5th edition of this classic book has been extensively revised and updated. Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

• Comprehensive coverage provides unparalleled discussion of disease processes.
• Extensive full-color art program illustrates disease processes and clinical manifestations of diseases.
• Life span content includes ten separate chapters for the pediatric content and special headings for aging content within the structures and functions chapters.
• "What's New?" boxes highlight the most current research and findings.
• "Nutrition and Disease" boxes show evidenced-based links between concepts of health promotion and disease.
• Algorithms throughout the text illustrate the sequential progression of disease processes.
• Detailed chapter outlines with page numbers provide easy access to content and overview of topics.
• Chapter introductions provide a rationale for learning the content about to be presented.
• Consistent presentation of each disease includes epidemiology, pathophysiology, clinical manifestations, and evaluation and treatment.
• Key terms are highlighted in each chapter and listed with page numbers for easy reference and chapter review.
• Chapter summaries provide concise synopses of key points and serve as a built-in content review.
• An "Introduction to Pathophysiology" provides an entrance to the study of disease and defines basic terms.

• More than 90 "What's New?" boxes present the most current research available.
• Includes approximately 310 new full-color illustrations.
• A new companion CD-ROM with over 750 review questions and answers and 20 animations.
• Now includes a comprehensive glossary of approximately 1,200 terms to help students with the often difficult terminology related to pathophysiology.
• Infection content is presented in a separate chapter to better organize content on mechanisms of self-defense.
• Extensive revisions and updates of every chapter, particularly: inflammation and immunity, stress, cancer, pain, the reproductive system, and urinary and renal systems alterations.

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Product Details

Elsevier Health Sciences
Publication date:
Edition description:
Older Edition
Product dimensions:
8.74(w) x 11.40(h) x 2.04(d)

Table of Contents

1Cellular biology1
2Altered cellular and tissue biology45
3The cellular environment : fluids and electrolytes, acids and bases93
4Genes and genetic diseases123
5Genes, environment - life-style, and common diseases157
6Innate immunity : inflammation175
7Adaptive immunity211
8Alterations in immunity and inflammation249
10Stress and disease311
11Biology of cancer333
12Tumor invasion and metastasis375
13Cancer in children403
14Structure and function of the neurologic system411
15Pain, temperature regulation, sleep, and sensory function447
16Concepts of neurologic dysfunction491
17Alterations of neurologic function547
18Neurobiology of schizophrenia, mood disorders, and anxiety disorders605
19Alterations of neurologic function in children623
20Mechanisms of hormonal regulation655
21Alterations of hormonal regulation683
22Structure and function of the reproductive systems735
23Alterations of the reproductive systems771
24Sexually transmitted infections863
25Structure and function of the hematologic system893
26Alterations of erythrocyte function927
27Alterations of leukocyte, lymphoid, and hemostatic function955
28Alterations of hematologic function in children999
29Structure and function of the cardiovascular and lymphatic systems1029
30Alterations of cardiovascular function1081
31Alterations of cardiovascular function in children1147
32Structure and function of the pulmonary system1181
33Alterations of pulmonary function1205
34Alterations of pulmonary function in children1249
35Structure and function of the renal and urologic systems1279
36Alterations of renal and urinary tract function1301
37Alterations of renal and urinary tract function in children1337
38Structure and function of the digestive system1353
39Alterations of digestive function1385
40Alterations of digestive function in children1447
41Structure and function of the musculoskeletal system1471
42Alterations of musculoskeletal function1497
43Alterations of musculoskeletal function in children1547
44Structure, function, and disorders of the integument1573
45Alterations of the integument in children1609
46Shock, multiple organ dysfunction syndrome, and burns in adults1625
47Shock, multiple organ dysfunction syndrome, and burns in children1655

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Pathophysiology 3 out of 5 based on 0 ratings. 14 reviews.
an-old-nursing-instructor More than 1 year ago
I have used this book in advanced practice preparation and practice. This book is for the individual with an intermediate background in pathophysiology and wants to know more. Nurses are life long learners and as you practice in your profession you will see things that you want to understand better so that you can critically think about what is going on with your clients. This book will help, DON'T throw the baby out with the bath water. Keep this book on your shelf until the thirst for knowledge needs to be quenched, then pick up this book and drink it all in.
Guest More than 1 year ago
I have to agree with some previous reviewers that it's very detailed and 'difficult'. The book outlines pathophysiology to chemical, cellular levels which sometimes get very complex. But that's the essences of this book. This book is not for beginner to learn the pathophysiology. To fully appreciate the fine details the book puts out, the reader must have absolute solid understanding of basic (and bit of intermediate) pathophysiology in addition to basic physioloy and biology. This book is not for quick reference purpose. It takes time to comprehend the complexity, but the human body is complex, too. But once you 'get it' you'll appreciate the knowledge the book revealed. Considering how complex the human body is, the book did a fine job of 'dividing' the body into chapters. So it's no surprising to me that I have to flip back and forth between chapters to understand something as a whole. I have been using this book since it's 2nd edition. It has gone through a lot of improvements, believe me. My husband and I are both critical care RNs and we both love it. I highly recommend this book for non-beginners. It is excellent reference book.
Guest More than 1 year ago
Others that have rated this book poorly didn't have much nursing background. This book is not appropriate for the student who hasn't completed a year of nursing school. Otherwise it is an good reference book but not the one I turn to the most.
Guest More than 1 year ago
I agree this is a bad text with important information buried in technical detail fit for a research scientist. I've never encountered another text this difficult to read. I have a degree in accounting and am taking this course as a prerequiste for a nursing program. There should have been prerequisites for this text.
Anonymous More than 1 year ago
I bought this book because its the book suggessted for reference for my graudate study. I think its very good. I would recommend it for advance pathophysiology course but for basics Medical Surgical Books are still the best.
Anonymous More than 1 year ago
Anonymous More than 1 year ago
Currently using book to assist in teaching class; previously used last edition. I find this version addresses certain phrases with better explanations, but in some topics the order of introduction is suboptimal. Many times certain subjects are explained in clearer ways significantly later in the same chapter. Diagrams are often arranged poorly in relation to the text; sheer number of images on certain pages is distracting from being able to read a topic without stopping.
Anonymous More than 1 year ago
The only problem was with the delivery time. This was for an online grad. level class. The delivery time was supposed to be 3 days. However, it took 7-8 days for the book to arrive. The first test was 2 days after the arrival.
Anonymous More than 1 year ago
SaveSweetCharity More than 1 year ago
I am currently taking advanced pathophysiology and I found this book to be a good source of basic information. But, since the book is published in 2006, it is lacking many new advancements in medicine. I find using current medical journals a much more accurate resource,
Anonymous More than 1 year ago
Guest More than 1 year ago
Very poorly written and difficult to comprehend.
Guest More than 1 year ago
Text is heavily populated with extensive details to the extent that the main idea on every subject is hard to find. I have to use other books in order to find clear explanations about pathophysiology. Quantity does not equal quality.
Guest More than 1 year ago
I am a nursing student and I bought this book for additional information on diseases. I find this book easier to read and better structured than the required text I have bought for my nursing classes. The pre and post chapter sections make this book easy to understand and complete!