Patient-Based Approaches to Cognitive Neuroscience / Edition 1

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The cognitive disorders that follow brain damage are an important source of insight into the neural bases of human thought. Although cognitive neuroscience is sometimes equated with cognitive neuroimaging, the patient-based approach to cognitive neuroscience is responsible for most of what we now know about the brain systems underlying perception, attention, memory, language, and higher-order forms of thought including consciousness. This volume brings together state-of-the-art reviews of the patient-based approach to these and other central issues in cognitive neuroscience, written by leading authorities.

Part I covers the history, principles, and methods of patient-based neuroscience: lesion method, imaging, computational modeling, and anatomy. Part II covers perception and vision: sensory agnosias, disorders of body perception, attention and neglect, disorders of perception and awareness, and misidentification syndromes. Part III covers language: aphasia, language disorders in children, specific language impairments, developmental dyslexia, acquired reading disorders, and agraphia. Part IV covers memory: amnesia and semantic memory impairments. Part V covers higher cognitive functions: frontal lobes, callosal disconnection (split brain), skilled movement disorders, acalculia, dementia, delirium, and degenerative conditions including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

Contributors: Michael P. Alexander, Russell M. Bauer, Kathleen Baynes, D. Frank Benson, H. Branch Coslett, Jeffrey L. Cummings, Tim Curran, Antonio R. Damasio, Hanna Damasio, Ennio De Renzi, Maureen Dennis, Mark D'Esposito, Martha J. Farah, Todd E.Feinberg, Michael S. Gazzaniga, Georg Goldenberg, Jordan Grafman, Kenneth M. Heilman, Diane M. Jacobs, Daniel I. Kaufer, Daniel Y. Kimberg, Maureen W. Lovett, Richard Mayeux, M.-Marsel Mesulam, Bruce L. Miller, Robert D. Nebes, Robert D. Rafal, Marcus E. Raichle, Timothy Rickard, David M. Roane, David J. Roeltgen, Leslie J. Gonzalez Rothi, Eleanor M. Saffran, Daniel L. Schacter, Karin Stromswold, Edward Valenstein, Robert T. Watson, Tricia Zawacki, Stuart Zola.

Disc. perception, attention, language, memory & higher func- tions; neuroanatomic, neuropschological & clinical issues.

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What People Are Saying

From the Publisher
"This is a stimulating synthesis of the theory and methodology of cognitive neuroscience and the clinical insights of behavioral neurology. With its concise treatments of a wide range of cognitive disorders, the book provides an invaluable and readable manual for both clinicians and non-clinicians, researchers and practitioners alike."—T. W. Robbins, Professor ofCognitive Neuroscience, University of Cambridge
T. W. Robbins

This is a stimulating synthesis of the theory and methodology of cognitive neuroscience and the clinical insights of behavioral neurology. With its concise treatments of a wide range of cognitive disorders, the book provides an invaluable and readable manual for both clinicians and non-clinicians, researchers and practitioners alike.

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Product Details

Meet the Author

Martha J. Farah is Walter H. Annenberg Professor of Natural Sciences in the Department of
Psychology at the University of Pennsylvania, where she directs the Center for Neuroscience &
Society. She has worked on many topics within neuroscience, including vision, prefrontal function,
emotion, and development. In her three decades of research she has witnessed the advent of functional neuroimaging, the burgeoning of cognitive neuroscience, and its expansion into the study of social and affective processes. She is now focusing her attention on the ethical, legal and social implications of these developments.

Todd E Feinberg M.D. is Professor of Clinical Neurology and Psychiatry atAlbert Einstein
College of Medicineand Chief, Yarmon Neurobehavior and Alzheimer's Disease Center,Beth Israel
Medical Center.

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Table of Contents

Ch. 1 A historical perspective on cognitive neuroscience 3
Ch. 2 Structural imaging of patients in cognitive neuroscience 21
Ch. 3 Functional imaging in cognitive neuroscience I : basic principles 35
Ch. 4 Functional imaging in cognitive neuroscience II : imaging patients 47
Ch. 5 Electrophysiological methods, including transcranial magnetic stimulation, in cognitive neuroscience 55
Ch. 6 Studying plasticity in the damaged and normal brain 85
Ch. 7 Computational modeling of patients in cognitive neuroscience 99
Ch. 8 Visual perception and visual imagery 111
Ch. 9 Visual object agnosia 117
Ch. 10 Prosopagnosia 123
Ch. 11 Visuospatial function 127
Ch. 12 Auditory agnosia and amusia 133
Ch. 13 Disorders of body perception and representation 147
Ch. 14 Neglect I : clinical and anatomical issues 157
Ch. 15 Neglect II : cognitive issues 167
Ch. 16 Aphasia I : clinical and anatomical issues 181
Ch. 17 Aphasia II : cognitive issues 199
Ch. 18 Aphasia III : rehabilitation 213
Ch. 19 Aphasia IV : acquired disorders of language in children 229
Ch. 20 Acquired disorders of reading 247
Ch. 21 The aprosodias 259
Ch. 22 Frontal lobes I : clinical and anatomical issues 273
Ch. 23 Frontal lobes II : cognitive issues 281
Ch. 24 Amnesia I : clinical and anatomical issues 289
Ch. 25 Amnesia II : cognitive issues 303
Ch. 26 Confabulation 315
Ch. 27 Semantic memory impairments 325
Ch. 28 Acalculia and number processing disorders 331
Ch. 29 Disorders of skilled movements : limb apraxia 341
Ch. 30 Callosal disconnection 349
Ch. 31 Alzheimer's disease 361
Ch. 32 Frontotemporal dementia 371
Ch. 33 Dementia in Parkinson's disease, Huntington's desease, and related disorders 381
Ch. 34 Mental retardation 397
Ch. 35 Attention deficit hyperactivity disorder 407
Ch. 36 Autism and related conditions 419
Ch. 37 Developmental reading disorders 433
Ch. 38 Molecular genetics of cognitive developmen 453
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