Phage and the Origins of Molecular Biology / Edition 1

Phage and the Origins of Molecular Biology / Edition 1

by John Cairns
     
 

ISBN-10: 0879698004

ISBN-13: 9780879698003

Pub. Date: 10/02/2007

Publisher: Cold Spring Harbor Laboratory Press

This hugely influential book, published in 1966 as a 60th birthday tribute to Max Delbr ck, is now republished in a 40th anniversary edition. In addition to the landmark collection of 35 essays by pioneers of molecular biology, this edition contains an additional essay by Sydney Brenner, one of the few influential molecular biologists of the time not to contribute

…  See more details below

Overview

This hugely influential book, published in 1966 as a 60th birthday tribute to Max Delbr ck, is now republished in a 40th anniversary edition. In addition to the landmark collection of 35 essays by pioneers of molecular biology, this edition contains an additional essay by Sydney Brenner, one of the few influential molecular biologists of the time not to contribute to the original book. The essay contains material prepared for the original edition, but not submitted at the time, and a newly written view of the phage group seen from the perspective of someone close to, but not an intimate member of, that famous school. This new edition also retains material added to the expanded 1992 edition, including Gunther Stent's obituary of Max Delbr ck, two commentaries on issues raised in the book reprinted from Scientific American and Science, and the preface in which John Cairns reflects on the book's creation and molecular biology's age of innocence. On first publication, the book was hailed as [introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle. As such, it is an important document in the history of biology... (Journal of History of Biology). And in another review it was described as required reading for every student of experimental biology... [who] will sense the smell and rattle of the laboratory (Bioscience). The book was a formative influence on many of today's leading scientists.

Read More

Product Details

ISBN-13:
9780879698003
Publisher:
Cold Spring Harbor Laboratory Press
Publication date:
10/02/2007
Edition description:
Anniversar
Pages:
416
Product dimensions:
6.40(w) x 9.60(h) x 1.20(d)

Table of Contents

Preface
IOrigins of Molecular Biology
Introduction: Waiting for the Paradox3
A Physicist Looks at Biology9
Biochemical Genetics: Some Recollections23
The Target Theory33
High Energy Phosphate Bonds: Optional or Obligatory?43
IIThe Phage Renaissance
Bacteriophage: One-Step Growth53
Electron Microscopy of Phages63
The Eclipse in the Bacteriophage Life Cycle79
The Prophage and I88
The Injection of DNA into Cells by Phage100
Transfer of Parental Material to Progeny109
Electron Microscopy of Developing Bacteriophage116
IIIPhage Genetics
Phenotypic Mixing133
Mating Theory142
On the Physical Basis of Genetic Structure in Bacteriophage150
Adventures in the rII Region157
Conditional Lethals166
IVBacterial Genetics
Mutations of Bacteria and of Bacteriophage173
Gene, Transforming Principle, and DNA180
Sexual Differentiation in Bacteria201
Bacterial Conjugation216
Story and Structure of the [lambda] Transducing Phage226
VDNA
Growing Up in the Phage Group239
Demonstration of the Semiconservative Mode of DNA Duplication246
The Autoradiography of DNA252
[Phi][chi]: Multum in Parvo258
The Relation between Nuclear and Cellular Division in Escherichia coli265
VIRamifications of Molecular Biology
The Mammalian Cell275
The Plaque Technique and the Development of Quantitative Animal Virology287
Quantitative Tumor Virology292
The Natural Selection Theory of Antibody Formation; Ten Years Later301
Cybernetics of the Insect Optomotor Response313
Terminal Redundancy, or All's Well that Ends Well335

Read More

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >