The Pharmacologic Management of Heart Disease / Edition 1

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Editorial Reviews

Doody's Review Service
Reviewer: Alex Lickerman, MD (University of Chicago Pritzker School of Medicine)
Description: This book summarizes the physiology, pathophysiology, and pharmacologic weapons used in the treatment of heart disease.
Purpose: The editors present their book to provide physicians who care for patients with heart disease with an up-to-date guide for the clinical application of pharmacologic advances. As the editors state, "...fortunately, the relentless march of discovery continues with the appearance of new drugs, new classes of drugs, new facts about old drugs, and new uses for some old drugs...." In fact, this "relentless march of discovery" threatens to leave many clinicians at best bewildered and at worst dangerous to the very patients they treat. This book represents an excellent preventative measure against becoming out-of-date.
Audience: The editors intend the book both for cardiologists and primary care physicians. However, residents, and even students, would do well to have it on their shelves.
Features: The authors' styles are consistently direct, clear, and unpretentious. The organization is logical and begins in each section at the beginning of the story, as in the first section, entitled Basic Concepts, which first offers a concise review of basic pharmacotherapy, including a discussion of principles every clinician should have at his or her fingertips. It moves on then to principles of pharmacotherapy of cardiac drugs, including the specific parameters of bioavailability, first-pass effects, and drug-drug interactions. The section entitled Lipid-Lowering Therapy appropriately begins with a review of the main classes of lipid-lowering agents. Reviews of landmark trials and meta-analyses follow. This organization enables the reader to build a knowledge of the material block by block in an order that greatly enhances understanding and retention.
Assessment: The authors have made good on their promise in the preface to "go beyond the scope of review articles on drug therapies" by offering detailed practical clinical pearls on how to prescribe cardiac drugs, monitor patients on them, adjust dosages, and mitigate side effects. From observational studies to randomized trials, from discussions of theoretical mechanisms of action to statistics of percent improved survival, the book delivers a multileveled comprehensive review that arms the clinician with all the knowledge he or she requires to treat heart disease effectively with pharmacotherapy. It does so based on the most cogent analyses of the most up-to-date data currently available, and I recommend the book for all physicians with patients who require pharmacologic therapy to treat heart disease.
Alex Lickerman
This book summarizes the physiology, pathophysiology, and pharmacologic weapons used in the treatment of heart disease. The editors present their book to provide physicians who care for patients with heart disease with an up-to-date guide for the clinical application of pharmacologic advances. As the editors state, ^^...fortunately, the relentless march of discovery continues with the appearance of new drugs, new classes of drugs, new facts about old drugs, and new uses for some old drugs....^^ In fact, this ^^relentless march of discovery^^ threatens to leave many clinicians at best bewildered and at worst dangerous to the very patients they treat. This book represents an excellent preventative measure against becoming out-of-date. The editors intend the book both for cardiologists and primary care physicians. However, residents, and even students, would do well to have it on their shelves. The authors' styles are consistently direct, clear, and unpretentious. The organization is logical and begins in each section at the beginning of the story, as in the first section, entitled Basic Concepts, which first offers a concise review of basic pharmacotherapy, including a discussion of principles every clinician should have at his or her fingertips. It moves on then to principles of pharmacotherapy of cardiac drugs, including the specific parameters of bioavailability, first-pass effects, and drug-drug interactions. The section entitled Lipid-Lowering Therapy appropriately begins with a review of the main classes of lipid-lowering agents. Reviews of landmark trials and meta-analyses follow. This organization enables the reader to build a knowledge of the material block by block in anorder that greatly enhances understanding and retention. The authors have made good on their promise in the preface to ^^go beyond the scope of review articles on drug therapies^^ by offering detailed practical clinical pearls on how to prescribe cardiac drugs, monitor patients on them, adjust dosages, and mitigate side effects. From observational studies to randomized trials, from discussions of theoretical mechanisms of action to statistics of percent improved survival, the book delivers a multileveled comprehensive review that arms the clinician with all the knowledge he or she requires to treat heart disease effectively with pharmacotherapy. It does so based on the most cogent analyses of the most up-to-date data currently available, and I recommend the book for all physicians with patients who require pharmacologic therapy to treat heart disease.
Booknews
Covers the field of cardiovascular drug therapeutics, beginning with an overview of basic pharmacological principles, then offering sections on preventive treatments; ischemic heart disease; thrombolytic, antithrombotic, and anticoagulant treatments; congestive heart failure; and antiarrhythmic treatments. Each section provides basic information on drugs, describing how to use them in practice, how to manage diseases with drugs, and how to avoid common pitfalls. For clinicians working with heart disease patients. Annotation c. Book News, Inc., Portland, OR (booknews.com)

5 Stars! from Doody
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Product Details

  • ISBN-13: 9780683047967
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 10/1/1996
  • Edition number: 1
  • Pages: 581

Table of Contents

Dedication
Preface
Foreword
Contributors
1 Principles and Practice of Pharmacotherapy 3
2 Lipid-Lowering Drugs 41
3 Primary and Secondary Prevention of Coronary Heart Disease 81
4 Principles of Therapy in Ischemic Heart Disease and Use of Antiischemic Drugs 121
5 Management of Patients with Stable Coronary Disease 147
6 Management of the Acute Phase of Myocardial Infarction and Unstable Angina 177
7 Long-Term Management and Secondary Prevention After Myocardial Infarction 191
8 Thrombolytics 223
9 Platelet-Active Drugs and Anticoagulants 279
10 Management of Cardiac Disorders with Antithrombotic Agents 303
11 Pharmacologic Intervention for the Treatment of Congestive Heart Failure 341
12 Drug Therapy to Prevent Congestive Heart Failure and Left Ventricular Remodeling 359
13 Treatment of Advanced Congestive Heart Failure 385
14 Antiarrhythmic Drugs 415
15 Pharmacologic Therapy for Supraventricular Arrhythmias 459
16 Management of Ventricular Arrhythmias 501
17 Drugs in Cardiopulmonary Resuscitation 523
Index 545
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