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Doody's Review ServiceReviewer: Linda Jacobs-Condit, AuD, CCC-A(George Washington University)
Description: This is a review of both basic and advanced topics critical to successful audiologic practice. Included are fundamental concepts and terminology of pharmacology, biochemistry of the auditory system, and mechanisms of toxicity. Also included are chapters specific to drug and noise-induced ototoxicity. The index is very thorough, as is the glossary of terms and a chapter devoted to current web sites and resources for pharmaceutical information.
Purpose: According to the author, the book is written for a wide audience that includes audiology students, practicing clinical audiologists, and research audiologists. The goal is to provide information on the basic concepts and terminology of pharmacology, as well as patient care factors, regulatory issues, and ototoxic monitoring. Each chapter is written by experts in the fields of pharmacology, pharmaceuticals, audiology, and/or otolaryngology, so that complex material could be readily understandable.
Audience: Dr. Campbell has over 30 years of clinical, research, teaching, and publication experience in the field of audiology. She holds several patents for otoprotective agents to prevent hearing loss caused by noise and exposure to ototoxic medications and radiation. She has recruited a group of contributors who are experts in the fields of audiology, pharmacology, and otolaryngology.
Features: The book first presents an overview of pharmacology, progressing through pharmacotherapeutics and patient care factors, and regulatory issues. There is a review of the FDA clinical trial and approval process and a review of the most common classes of drugs used in otolaryngologic practice, as well as the rules and regulations regarding the use of herbal supplements. Subsequent chapters cover mechanisms of toxicity, biochemical bases of hearing, and reversal of hearing loss through hair cell regeneration. This leads to a discussion of patient management (including audiologic monitoring for ototoxicity), otoprotective and rescue agents, and of breakthroughs in research, web sites and resources for pharmaceutical information, patient support groups and organizations. The glossary of terms is excellent, as are the color photos of the cochlea and brainstem.
Assessment: This is the only book on pharmacology and ototoxicity written specifically for audiologists. Numerous figures and photos support understanding, as well as a thorough reference review, and a glossary of key terms that accompanies each chapter. Also included is information on new areas emerging in audiology research relevant to ototoxicity and pharmacology.