Pharmacology and Ototoxicity for Audiologists / Edition 1

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This highly anticipated text is the only publication on pharmacology and ototoxicity written specifically for audiologists. With contributions from leading audiologists, basic scientists, pharmacologists, and otolaryngologists, Pharmacology and Ototoxicity for Audiologists provides both basic and advanced coverage of topics critical to successful clinical practice. Fundamental concepts and terminology of pharmacology, biochemistry of the auditory system, and mechanisms of toxicity are covered, along with specific chapters on drug and noise-induced ototoxicity. This text is absolutely essential for anyone working in the hearing sciences and hearing healthcare.

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Editorial Reviews

Doody's Review Service
Reviewer: Linda Jacobs-Condit, AuD, CCC-A(George Washington University)
Description: This is a review of both basic and advanced topics critical to successful audiologic practice. Included are fundamental concepts and terminology of pharmacology, biochemistry of the auditory system, and mechanisms of toxicity. Also included are chapters specific to drug and noise-induced ototoxicity. The index is very thorough, as is the glossary of terms and a chapter devoted to current web sites and resources for pharmaceutical information.
Purpose: According to the author, the book is written for a wide audience that includes audiology students, practicing clinical audiologists, and research audiologists. The goal is to provide information on the basic concepts and terminology of pharmacology, as well as patient care factors, regulatory issues, and ototoxic monitoring. Each chapter is written by experts in the fields of pharmacology, pharmaceuticals, audiology, and/or otolaryngology, so that complex material could be readily understandable.
Audience: Dr. Campbell has over 30 years of clinical, research, teaching, and publication experience in the field of audiology. She holds several patents for otoprotective agents to prevent hearing loss caused by noise and exposure to ototoxic medications and radiation. She has recruited a group of contributors who are experts in the fields of audiology, pharmacology, and otolaryngology.
Features: The book first presents an overview of pharmacology, progressing through pharmacotherapeutics and patient care factors, and regulatory issues. There is a review of the FDA clinical trial and approval process and a review of the most common classes of drugs used in otolaryngologic practice, as well as the rules and regulations regarding the use of herbal supplements. Subsequent chapters cover mechanisms of toxicity, biochemical bases of hearing, and reversal of hearing loss through hair cell regeneration. This leads to a discussion of patient management (including audiologic monitoring for ototoxicity), otoprotective and rescue agents, and of breakthroughs in research, web sites and resources for pharmaceutical information, patient support groups and organizations. The glossary of terms is excellent, as are the color photos of the cochlea and brainstem.
Assessment: This is the only book on pharmacology and ototoxicity written specifically for audiologists. Numerous figures and photos support understanding, as well as a thorough reference review, and a glossary of key terms that accompanies each chapter. Also included is information on new areas emerging in audiology research relevant to ototoxicity and pharmacology.
From the Publisher
The information is covered in the Diagnostics and the Medical Aspects course. I think this area of study is gaining interest in the profession, particularly due to the ground-breaking and cutting-edge research undertaken by the author.
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Product Details

  • ISBN-13: 9781418011307
  • Publisher: Cengage Learning
  • Publication date: 8/25/2006
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 440
  • Sales rank: 949,853
  • Product dimensions: 7.90 (w) x 9.30 (h) x 0.90 (d)

Meet the Author

Kathleen Campbell, Ph.D., is Professor and Director of Audiology Research at Southern Illinois University School of Medicine in Springfield, Il. She directed and provided audiology services for over 20 years in Canada and the United States but now focuses primarily on both basic and clinical research. For over 20 years, she has also taught audiology to faculty, residents, and medical students in otolaryngology, pediatrics, neurology, primary care, neonatology, and surgery. She is the author of Essential Audiology for Physicians and numerous book chapters and articles. She currently serves on the American Academy of Audiology Board of Directors. She consults in audiology clinical management, clinical trials, and as an expert witness. Dr. Campbell is also a prolific researcher, publishing numerous articles on both basic science and clinical topics in various areas of auditory science and auditory disorders. She is a noted lecturer both nationally and internationally focusing on audiologic assessment of auditory disorders, and particularly ototoxicity, noise-induced hearing loss and otoprotective agents. She has received an NIH Clinical Investigator Development Award, the James A. Shannon Director's Award from NIH for her research in ototoxicity, a Special Presidential Citation from the American Academy of Audiology for her work in Professional Practice Standards, has been named an ASHA Fellow and is in Who's Who in America. Dr. Campbell also holds several patents for otoprotective agents and is planning clinical trials. Dr. Campbell recently received the 2004 Copper Black Award for Creative Achievement from American Mensa for her work in otoprotective agents.

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Table of Contents

Overview Pharmacology Chapter 1: Michael Meldrum, PhD, Pharmacodynamics University of Florida: Introduction to Pharmacology Chapter 2: Jose Rey PharmD: Pharmacokinetics and Pharmacodynamics, dose response considerations Chapter 3: Tabitha Parent Buck, AuD; Henry P. Trahan, AuD; O.T. Wendel, PhD: Pharmacotherapeutics and Patient Factors Chapter 4: Venkatesh Atul Bhattaram, PhD Rajanikanth Madabushi,PhD and Hartmut Derendorf, PhD The Food and Drug Administration and the Drug Approval Process Chapter 5: Karen Doyle, MD: Common Classes of Drugs used in Otolaryngologic Practice Chapter 6: Michael Seidman, MD: Nutraceuticals and Herbal Supplements (Including the DSHEA act) Chapter 7: Richard Bobbin, PhD, Jean Luc Puel, and Post Doc: Mechanisms of Toxicity including physical, free radical: Oxidative and Anti-oxidative Mechanisms, protein interactions, and defense mechanisms Chapter 8: Sandra McFadden, PhD: Biochemical Bases of Hearing including cochlear biochemistry, overview of neurotransmitters and neurotransmitters of the auditory System Chapter 9: A.U. Bankaitis,PhD, Robert J. Kemp, MBA "Infection Control in the Audiology Clinic" Drug and Noise-induced Ototoxicity Chapter 10: Len Rybak, MD, PhD, Xinyan Huang, MD and Kathleen Campbell, PhD: Cancer and Ototoxicity of Chemotherapeutics Chapter 11: Jochen Schacht, PhD Aminoglycoside Ototoxicity: review of actions and aminoglycoside Antibiotic Ototoxicity Chapter 12: Len Rybak MD, PhD: Renal function and Ototoxicity of Loop Diuretics Chapter 13: Brenda Lonsbury Martin: Temporary and permanent ototoxicity of aspirin, quinine, non-steroidal anti-inflammatory drugs, and the macrolides Chapter 14: BenoƮt Pouyatos PhD, Larry Fechter, PhD: Industrial Chemicals and Solvents affecting the Auditory System Chapter 15: Don Henderson, PhD: Cellular Mechanisms of Noise-Induced Hearing Loss Chapter 16: Barbara Cone-Wesson, PhD: Alcohol, Drug Exposure, and Nutritional Influences on Hearing and Speech Development Chapter 17: Steve Fausti, PhD: Audiologic Monitoring for Ototoxicity and Patient Management Chapter 18: Owen Black, MD, Susan Pesznecker RN: Mechanisms of Vestibular Toxicity including review of nausea and vomiting Chapter 19: Jaynee Handelsman, PhD: Audiologic Findings in Vestibular Toxicity New Directions: Chapter 20: Kathleen Campbell PhD and Len Rybak, MD, PhD: Otoprotective and Rescue Agents Chapter 21: Brenda Ryals, PhD: Regeneration of Hair Cells Chapter 22: Sharon Kujawa PhD and William Sewell PhD: Using Drugs as Tools to Investigate the Auditory System Chapter 23: Robert DiSogra AuD Staying Current: Websites and Resources for Pharmaceutical Information, Patient Support Groups and Organizations

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