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Doody's Review ServiceReviewer: Thomas L. Pazdernik, PhD (University of Kansas Medical Center)
Description: This book is just as the title states and stands alone as the first to use an understanding of pharmacology principles to integrate the most recent advances in basic biomedical sciences into the rational use of the most appropriate medications to treat illness and preserve health in the practice of medicine.
Purpose: The editors have selected preeminent leaders in the field to generate a new type of textbook where basic science principles are used in the development of rational therapeutic treatments grounded in evidence-based medicine to optimize the treatment of patients with a look forward to the future use of personalized medicine. They have done an outstanding job of meeting this objective.
Audience: This book targets a broad audience from the most basic scientist, to those involved in drug discovery research and translational research, to teachers of the practice of medicine.
Features: The first part deals with principles and the second part with practice. The principles section covers the pharmacotherapeutic continuum, molecular pharmacology, systems pharmacology, and clinical pharmacology. The practice section contains not only the traditional topics found in most pharmacology books, such as cardiovascular therapeutics, psychopharmacologic therapeutics, etc., but also cutting-edge topics such as pharmacogenetics and pharmacogenomics, regenerative pharmacology, and stem cell therapies, all looking forward to implementing the emerging field of individualized medicine across medical specialties. The figures and tables used throughout the book are informative and of the highest quality. An online version is available via an access code for a web site. In all respects, this book is of the highest quality in content and appearance.
Assessment: This is an outstanding textbook that connects the recent advances in basic principles with the practice of medicine. It is a must-have book for those involved in drug discovery, translational research, and the teaching of evidence-based medicine, so practitioners can make sound clinical decisions from evidence-based therapeutic guidelines. I give this book my highest recommendation.