Pheochromocytoma: Pathophysiology and Clinical Management

Hardcover (Print)
Not Available on


Pheochromocytomas are rare, mostly benign tumors of the adrenal medulla whose symptoms are caused by a tumor-induced secretion of catecholamines. This book provides an overview of current knowledge on the clinical situation, diagnosis and therapy of the disease as well as an extensive discussion of novel aspects in the molecular basis of this disease such as the recognition of new tools in molecular biology. The endocrine diagnosis is based on precise knowledge of tumor metabolism of catecholamines and their metabolites and today comprises laboratory methods with a high sensitivity and specificity. As approximately one quarter of these tumors arise in the context of a familial disease, such as multiple endocrine neoplasia type 2, von Hippel-Lindau syndrome, neurofibromatosis type 1 or familial paragangliomas, the genetic diagnosis is becoming increasingly relevant. Equally indispensable are imaging methods such as 123I-MIBG scintigraphy or octreotide scintigraphy, which can be employed as a complementary approach in e.g. malignant tumors. The surgical therapy is clearly based on the nature of the disease; in sporadic unilateral as well as familial bilateral pheochromocytoma a lateral endoscopic approach is chosen. The treatment of malignant pheochromocytoma is mainly based on the use of nuclear medical techniques and selected chemotherapeutic approaches. This book is essential reading for clinicians and scientists in the fields of endocrinology as well as oncology, surgery and nuclear medicine.

Read More Show Less

Product Details

  • ISBN-13: 9783805576246
  • Publisher: Karger, S. Inc.
  • Publication date: 1/28/2004
  • Series: Frontiers of Hormone Research Ser.
  • Edition description: REV
  • Pages: 168
  • Product dimensions: 6.90 (w) x 9.60 (h) x 0.50 (d)

Table of Contents

Principles of Catecholamine Biosynthesis, Metabolism and Release 1
Pathogenesis of Pheochromocytoma 26
The Genetic Basis of Pheochromocytoma 45
The Clinical Presentation (Symptoms and Signs) of Sporadic and Familial Chromaffin Cell Tumours (Phaeochromocytomas and Paragangliomas) 61
Biochemical Diagnosis of Pheochromocytoma 76
Diagnostic Imaging of Pheochromocytoma 107
Preoperative and Surgical Therapy in Sporadic and Familial Pheochromocytoma 121
Somatostatin Receptors in Pheochromocytoma 145
Malignant Pheochromocytoma 155
Author Index 163
Subject Index 164
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)