Photosensitive Molecules for Controlling Biological Function / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$117.31
Used and New from Other Sellers
Used and New from Other Sellers
from $111.40
Usually ships in 1-2 business days
(Save 19%)
Other sellers (Hardcover)
  • All (4) from $111.40   
  • New (4) from $111.40   

More About This Textbook

Overview

The development of new phohemical tools, some synthesized by chemists and some provided by nature, is rapidly changing the way neurobiological research is performed in the modern laboratory. In Photosensitive Molecules for Controlling Biological Function, expert researchers in the field examine the most cutting-edge tools currently available. Divided into three sections, this detailed compendium features techniques involving natural photosensitive proteins, caged neurotransmitters, and small molecule photoswitches that bestow light sensitivity on ion channels and receptors. Written for the Neuromethods series, this volume features the type of meticulous description and implementation advice that is crucial for getting optimal results in the lab.

Authoritative and practical, Photosensitive Molecules for Controlling Biological Function provides an unbiased comparison of the various phohemical tools currently available for controlling neuronal activity in order to aid scientists in the vital goal of choosing the right tools for the right job.

Read More Show Less

Product Details

  • ISBN-13: 9781617790300
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 3/3/2011
  • Series: Neuromethods Series , #55
  • Edition description: 2011
  • Edition number: 1
  • Pages: 298
  • Product dimensions: 7.10 (w) x 10.20 (h) x 0.90 (d)

Table of Contents

Part I: Photoreactive Small Molecules for Affecting Biological Function

1. Introduction to Part I: Caged Neurotransmitters

James J. Chambers and Richard H. Kramer

2. Targeting and Excitation of Photoactivatable Molecules: Design Considerations for Neurophysiology Experiments

Eugene F. Civillico, J. Peter Rickgauer, and Samuel S.-H. Wang

3. Are Caged Compounds Still Useful?

Graham C.R. Ellis-Davies

4. Chromophores for the Delivery of Bioactive Molecules with Two-Photon Excitation

Timothy M. Dore and Hunter C. Wilson

Part II: Imparting Light Sensitivity on Cells Using Photosensitive Proteins

5. Introduction to Part II: Natural Photosensitive Proteins

James J. Chambers and Richard H. Kramer

6. Light-Activated Ion Pumps and Channels for Temporally-Precise Optical Control of Activity in Genetically-Targeted Neurons

Brian Y. Chow, Xue Han, Jacob G. Bernstein, Patrick E. Monahan, and Edward S. Boyden

7. Vertebrate and Invertebrate Rhodopsins: Light Control of G Protein Signaling

Davina V. Gutierrez, Eugene Oh, and Stefan Herlitze

8. Restoring Visual Function after Photoreceptor Degeneration: Ectopic Expression of Photosensitive Proteins in Retinal Neurons

Bin Lin and Richard H. Masland

Part III: Molecular Photoswitch Conjugates to Remotely Affect Activity

9. Introduction to Part III: Small Molecule Photoswitches

James J. Chambers and Richard H. Kramer

10. Photoswitch Design

Andrew A. Beharry and G. Andrew Woolley

11. Photoswitchable Voltage-Gated Ion Channels

Doris L. Fortin and Richard H. Kramer

12. Optical Manipulation of Protein Activity and Protein Interactions Using Caged Proteins and Optical Switch Protein Conjugates

Yuling Yan and Gerard Marriott

13. Structure-Based Design of Light-Controlled Proteins

Harald Janovjak and Ehud Y. Isacoff

14. Photoswitchable Ligand-Gated Ion Channels

Pau Gorostiza and Ehud. Y. Isacoff

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)