Physics in Nuclear Medicine / Edition 3

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Overview

Experts in their fields provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using radioactively labeled tracers. They examine every aspect of the field—from basic atomic physics through radioactivity, isotope production, interaction of radiation with matter, radiation detection, and imaging systems. Examples are presented with solutions worked out in step-by-step detail, illustrating important concepts and calculations.

• Features a brand-new author, Dr. Simon Cherry, who contributes his cutting-edge knowledge in nuclear medicine instrumentation.

• Presents a new introductory chapter, "What is Nuclear Medicine."

• Revises and updates all chapters and appendices.

• Discusses the hottest topics in the field, including isotope production and tracer synthesis · image quality in nuclear medicine · tomographic reconstruction in nuclear medicine · SPECT · PET · computers in nuclear medicine · and more.

• Explains the analytic equations that describe the physics involved and illustrates them with graphs to make the material accessible to the non-math expert.

• Provides more advanced mathematics and concepts in appendices.

• Includes many new illustrations and examples throughout.

• Reorganizes several chapters, providing a more logical flow of information.

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Editorial Reviews

Doody's Review Service
Reviewer: Lawrence E. Williams, BSc, MSc, PhD (City of Hope National Medical Center)
Description: With Simon Cherry as new lead author, this third edition is a larger-format updating of the previous (1987) version of a very popular imaging textbook. The book covers a range of topics from atomic structure through counting statistics and on to radiation safety.
Purpose: This is intended as an introductory text in the physical technology of nuclear medicine. As such, it covers the physics and instrumentation in sufficient depth to be useful to trainees and students, but not at such depth that only the specialist would be interested in the results. Multiple printings of the second edition have attest to the success of the authors in fulfilling their goal. The new version updates primarily the growth areas of SPECT and PET imaging and is needed due to the 15 years since the prior version.
Audience: The main audience consists of medical physics students and practicing imaging physicists. The authors imagine the book more generally in the training of physicians, technologists, and scientists. This edition is more mathematical than the prior versions which could limit application in any such broad gamut of readers. I see some use by residents in nuclear medicine and radiology in their training and board exam preparation. Likewise, the practicing therapy physicist and radiation oncologist would find the SPECT and PET chapters providing important information on physiological imaging in treatment planning and follow-up. The authors are all well known in their field and provide contemporary information.
Features: The book covers a range of topics from atomic structure through to counting instruments and imaging devices such as gamma cameras and PET scanners. The best features are the new SPECT and PET chapters. Additionally, there is now a history and nuclear medicine current practice chapter. The index is excellent and references now include Internet sites. A number of worked examples appear in the text. No nuclear therapy is described in the dosimetry chapter and Monte Carlo techniques are not mentioned.
Assessment: This is — and probably has been — the standard textbook in its field. A third edition is justified due to the rapid changes in SPECT and PET imaging in the past 15 years. Its depth is appropriate for the majority of the student scientist audience. The authors' statement that the present version does not require knowledge of calculus is arguable. Many principles are (rightly) stated in the form of integrals or differential equations.
From the Publisher
"This new edition of 'Physics in Nuclear Medicine' is organized well and written clearly. It accomplishes the authors' goal of providing a single volume that serves as both a textbook for radiology residents, scientists, and technologists, and a reference for physicians and scientists in related fields. Overall, the authors have done an excellent job of elucidating the expanding and complex role of physics principles in nuclear medicine." Radiology, March 2005, p. 878

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780721683416
  • Publisher: Elsevier Health Sciences
  • Publication date: 8/12/2003
  • Edition description: REV
  • Edition number: 3
  • Pages: 544
  • Product dimensions: 7.58 (w) x 10.32 (h) x 1.03 (d)

Meet the Author

Professor, Department of Biomedical Engineering, University of California - Davis, Davis, CA

Emeritus Professor of Medical Physics, University of Wisconsin - Madison, Madison, WI

Norton Simon Professor, Chair, Department of Molecular and Medical Pharmacology, Chief, Division of Nuclear Medicine, UCLA School of Medicine, Los Angeles, CA

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Table of Contents

CHAPTER 1: What is Nuclear Medicine
a. Fundamental Concepts b. The Power of Nuclear Medicine c. Historial Overview d. Current Practice of Nuclear Medicine e. The Role of Physics in Nuclear Medicine

CHAPTER 2: Basic Atomic and Nuclear Physics
a. Quantities and Units b. Radiation c. Atoms d. Nucleur

CHAPTER 3: Modes of Radioiactive Decay
a. General Concepts b. Chemistry and Radioactivity c. Decay by Emission d. Isomeric Transition and Internal Conversion e. Electron Capture and Decay f. Positron and Decay g. Competitive and EC Decay h. Decay by Emission and Nuclear Fission i. Decay Modes and the Line of Stability j. Sources of Information on Radionuclides

CHAPTER 4: Decay of Radioactivity
a. Activity b. Exponential Decay c. Methods for Determining Decay Factors d. Image-Frame Decay Corrections e. Specific Activity f. Decay of a Mixed Radionuclide Sample g. Parent-Daughter Decay

CHAPTER 5: Isotope Production and Tracer Synthesis
a. Reactor-Produced Radionuclides b. Accelerator-Produced Radionuclides c. Radionuclide Generators d. Equations for Radionuclide Production e. Radionuclides for Nuclear Medicine f. Radiiopharmaceuticals for Clinical Applications

CHAPTER 6: Interaction of Radiation with Matter
a. Interactions of Charged Particles with Matter b. Charged-Particle Ranges c. Passage of High-Energy Photons Through Matter d. Attenuation of Photon Beams

CHAPTER 7: Radiation Detectors
a. Gas-filled Detectors b. Semi-conductor Detectors c. Scintillation Detectors

CHAPTER 8: Electronic Instrumentation for Radiation Detection
a. Preamplifiers b. Amplifers c. Pulse-Height Analyzers d. Time-to-Amplitude Converters e. Digital Counters and Ratemeters f. Coincidence Units g. High-Voltage Power Supplies h. Nuclear Instrument Modules i. Cathode Ray Tube j. Oscilloscopes k. Computer Monitors

CHAPTER 9: Nuclear Counting Statistics
a. Types of Measurement Error b. Nuclear Counting Statistics c. Propagation of Errors d. Applications of Statistical Analysis e. Statistical Tests

CHAPTER 10: Pulse Height Spectrometry
a. Basic Principles b. Spectrometry with Nal c. Spectrometry with other Detectors

CHAPTER 11: Problems in Radiation Detection and Measurement
a. Detection Efficiency b. Problems in the Detection and Measurement of Particles c. Deadtime d. Qualtity Assurance for Radiation Measureme Systems

CHAPTER 12: Counting Systems
a. Nal Well Counter b. Counting with Conventional Nal Detectors c. Liquid Scintillation Counters d. Gas-filled Detectors e. Semiconductor Detector Systems f. In Vivo Counting Systems

CHAPTER 13: The Gamma Camera: Basic Principles
a. General Concepts of Radionuclide Imaging b. Basic Principles of the Anger Camera

CHAPTER 14: Gamma Camera Performance Characteristics
a. Basic Performance Characteristics b. Detector Limitations: Nonuniformity and Nonlinearit c. Design and Performance Characteristics of Parellel-Hole Collinators d. Performance Characteristics of Converging, Diverging and Pinhole Collimators e. Measurements of Camera Performance

CHAPTER 15: Image Quality in Nuclear Medicine
a. Basic Methods for Characterizing and Evaluating Image Quality b. Spatial Resolution c. Contrast d. Noise e. Detectability and Observer Performance Studies

CHAPTER 16: Tomographic Reconstruction in Nuclear Medicine
a. General Concepts, Notation and Terminology b. Backprojection and Fourier-Based Techniques c. Image Quality in FT and FBP Techniques d. Iterative Reconstruction Algorithms e. Reconstruction of Fan-Beam and Cone-Beam Data

CHAPTER 17: Single Photon Emission Computed Tomography
a. SPECT Systems b. Practical Implementation of SPECT
c. Performance Characteristics of SPECT Systems d. Clinical Applications of SPECT

CHAPTER 18: Positron Emission Tomography
a. Annihilation Coincidence Detectioin b. PET Detector and Scanner Designs c. Dataa Acqusition for PET
d. Data Corrections and Quantitative Aspects of PET
e. Clinical and Research Applications of PET

CHAPTER 19: Computers in Nuclear Medicine

CHAPTER 20: Internal Radiation Dosimetry

CHAPTER 22: Radiation Safety and Health Physics

CHAPTER 23: Summary

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