Physics in Nuclear Medicine: Expert Consult - Online and Print / Edition 4

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Physics in Nuclear Medicine - by Drs. Simon R. Cherry, James A. Sorenson, and Michael E. Phelps - provides current, comprehensive guidance on the physics underlying modern nuclear medicine and imaging using radioactively labeled tracers. This revised and updated fourth edition features a new full-color layout, as well as the latest information on instrumentation and technology. Stay current on crucial developments in hybrid imaging (PET/CT and SPECT/CT), and small animal imaging, and benefit from the new section on tracer kinetic modeling in neuroreceptor imaging. What’s more, you can reinforce your understanding with graphical animations online at, along with the fully searchable text and calculation tools.

  • Master the physics of nuclear medicine with thorough explanations of analytic equations and illustrative graphs to make them accessible.
  • Discover the technologies used in state-of-the-art nuclear medicine imaging systems
  • Fully grasp the process of emission computed tomography with advanced mathematical concepts presented in the appendices.
  • Utilize the extensive data in the day-to-day practice of nuclear medicine practice and research.

Tap into the expertise of Dr. Simon Cherry, who contributes his cutting-edge knowledge in nuclear medicine instrumentation.

  • Stay current on the latest developments in nuclear medicine technology and methods
  • New sections to learn about hybrid imaging (PET/CT and SPECT/CT) and small animal imaging.
  • View graphical animations online at, where you can also access the fully searchable text and calculation tools.
  • Get a better view of images and line art and find information more easily thanks to a brand-new, full-color layout.

The perfect reference or textbook to comprehensively review physics principles in nuclear medicine.

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Editorial Reviews

From the Publisher

Review of the third edition from Radiology by RSNA-

"…This new edition of Physics in Nuclear Medicine is organized well and written clearly. It accomplishes the authors’ goal of providing a single volume that serves as both a textbook for radiology residents, scientists, and technologists and a reference for physicians and scientists in related fields. Overall, the authors have done an excellent job of elucidating the expanding and complex role of physics principles in nuclear medicine."

Reviewed by Joseph Kalen, PhD

'This is the fourth edition in the series which continues to address the main themes of describing Physics theory in Nuclear Medicine...The book continues to provide good introduction to Physics of Nuclear Medicine, making it suitable for...mainly postgraduate students, but is also agood reference for undergraduates in a scientific field.

The book itself is easy to follow and read with the inclusion of numerous questions/answers and examples scattered throughout each chapter...useful for revision. The organisation of the text and paragraphing makes it reader friendly and inviting.'

Radiography, June 2012

"This classic text on nuclear medicine physics, now in it's fourth edition, continues to build on on the success of the previous editions...The text is well written and the plentiful illustrations are clear and well placedto aid understanding of the physical concepts. The authors have made a tremendous effort into making physics accessible to non-physicists...All in all, this new edition of the book continues to cement its position as the definitive entry text for nuclear medicine physics. It is comprehensive, yet easy to read and belongs on the bookselves of anyone whose work involves using radionuclides in medicine."

RAD, December 2012

"Like its predecessors, this edition is a comprehensive, authoritative, and clearly written didactic book on the physics and technology of nuclear medicine. Dr. Cherry and his coauthors convey even complex mathematical subject matter in a style understandable to nonphysicists. Moreover, they are able to relate the quality and information content of nuclear medicine images to underlying physical principles in a generally understandable manner. It deservedly remains THE standard for introductory textbooks on nuclear medicine physics and instrumentation." - Pat B Zanzonico, PhD(Memorial Sloan-Kettering Cancer Center) Doody 4 star rating!

Doody's Review Service
Reviewer: Pat B Zanzonico, PhD (Memorial Sloan-Kettering Cancer Center)
Description: This high-quality book is the fourth edition of a detailed exposition, by three internationally recognized authorities, of physics, instrumentation, and data processing in nuclear medicine.
Purpose: As stated in the preface, the intent remains the same as it was for the first edition in 1980: to provide a didactic textbook on the physics and instrumentation of nuclear medicine that will be useful both as an introduction for trainees and other newcomers and as a reference for specialists in the field.
Audience: In both breadth and depth, it is suitable as an introductory textbook for residents, fellows, and other physician and nonphysician trainees, such as technologists, medical physics undergraduate and graduate students, and postdoctoral residents and fellows in nuclear medicine. As a reference, it is useful for practicing nuclear medicine physicians, radiologists, and medical physicists. It should be noted, however, that some of the material (for example, on tomographic image reconstruction and kinetic modeling) is more mathematical and more in depth than typically found in introductory books and, thus, may be challenging for technologists and some undergraduate students, as well as radiology residents on a nuclear medicine rotation.
Features: After a brief general introduction to field of nuclear medicine, the book progresses logically, covering the underlying physical principles (atomic and nuclear physics, radioactivity, radionuclide production, interactions of radiation with matter) of the field. Subsequent chapters address the technical bases (electronics, statistics, pulse-height spectrometry, detectors, and counting systems) of detecting and measuring nuclear radiations and the design, operating principles, and performance of clinical and preclinical nuclear medicine imaging instruments (including gamma cameras, SPECT and PET scanners, and multimodality devices). Other chapters address tomographic image reconstruction, image quality, tracer kinetic modeling, internal radiation dosimetry, and radiation safety, respectively. Each chapter concludes with a small number of references and suggested additional readings. The book uses hundreds of high-quality figures and tables and hundreds of equations, clearly set off from the text and with all parameters explicitly defined. Dozens of clearly presented, and invaluable, solved problems are included as well. Importantly, this revised and updated fourth edition features a new full-color layout, with many color photographs and nuclear medicine images. The color layout is not only aesthetically pleasing, it also is effective in emphasizing and otherwise conveying key features of the figures. With this edition, the text is now accessible and searchable on any internet-ready device via, which also includes numerous relevant graphic animations, graphing tools, and calculators. It is also available as a PDF file and as an eBook.
Assessment: Like its predecessors, this edition is a comprehensive, authoritative, and clearly written didactic book on the physics and technology of nuclear medicine. The chapters on electronics, image quality, multimodality imaging, and pharmacokinetic modeling are unique for such a book and are particularly noteworthy. There is, however, a paucity of material on radionuclide therapy in general, and three-dimensional radionuclide dosimetry in particular, topics of increasing practical importance. Further, other than the addition of a chapter on multimodality imaging and updating of the material on SPECT and PET scanners, the content is largely unchanged from that of the previous editions. However, Dr. Cherry and his coauthors convey even complex mathematical subject matter (for example, tomographic image reconstruction) in a style understandable to nonphysicists. Moreover, they are able to relate the quality and information content of nuclear medicine images to underlying physical principles in a generally understandable manner. These features distinguish this book from the many other competing books currently available. It deservedly remains THE standard for introductory textbooks on nuclear medicine physics and instrumentation.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781416051985
  • Publisher: Elsevier Health Sciences
  • Publication date: 4/26/2012
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 544
  • Sales rank: 796,926
  • Product dimensions: 7.40 (w) x 10.50 (h) x 1.10 (d)

Meet the Author

Professor, Department of Biomedical Engineering, University of California - Davis, Davis, CA

Emeritus Professor of Medical Physics, University of Wisconsin - Madison, Madison, WI

Norton Simon Professor, Chair, Department of Molecular and Medical Pharmacology, Chief, Division of Nuclear Medicine, UCLA School of Medicine, Los Angeles, CA

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Table of Contents

1. What is Nuclear Medicine?

2. Basic Atomic and Nuclear Physics

3. Modes of Radioactive Decay

4. Decay of Radioactivity

5. Radionuclide and Radiopharmaceutical Production

6. Interaction of Radiation with Matter

7. Radiation Detectors

8. Electronic Instrumentation for Radiation Detection Systems

9. Nuclear Counting Statistics

10. Pulse-Height Spectrometry

11. Problems in Radiation Detection and Measurement

12. Counting Systems

13. The Gamma Camera: Basic Principles

14. The Gamma Camera: Performance Characteristics

15. Image Quality in Nuclear Medicine

16. Tomographic Reconstruction in Nuclear Medicine

17. Single Photon Emission Computed Tomography

18. Positron Emission Tomography

19. Hybrid Imaging: SPECT/CT and PET/CT

20. Digital Image Processing in Nuclear Medicine

21. Tracer Kinetic Modeling

22. Internal Radiation Dosimetry

23. Radiation Safety and Health Physics

Appendice A

Appendice B

Appendice C

Appendice D

Appendice E

Appendice F

Appendice G

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