Physiological Basis of Aging and Geriatrics / Edition 4

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Overview

Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields.

New updated information includes:

  • emphasis on emerging technologies and recent advances in biology and bioengineering that allow greater and longer independence of the elderly
  • recent therapeutic developments in key diseases such as Alzheimer's, osteopenia, osteoporosis, high cholesterol, diabetes, gastritis, sexual impotence, and using transgenic animals as models of aging
  • evaluation of the latest knowledge on the roles of oxidants and antioxidants, and correlates them with other aging-based theories
  • expanded discussion of nutrition and physical exercise
  • chapters on gene and stem cell interventions related to the aging process
  • updated tables to reflect current trends, new research data, and up-to-date statistical information

Extensively revised and updated to reflect the current state of knowledge in the study of aging, the third edition of the bestselling Physiological Basis of Aging and Geriatrics provides an even more complete profile of the aging of individuals and populations. It includes aspects of demographic, comparative, and differential aging together with a discussion of the several theories of aging. It shows how body functions change with aging, describes how both genetic and environmental factors influence aging-related changes, and addresses some of the clinical consequences of these changes for health and longevity.Divided into three main sections, the book first provides a broad and solid background in basic processes of biogerontology. Then it presents a survey of the aging of body systems, focusing on maintenance of optimal function and ability to adapt to environmental demands. Finally, it provides a synopsis of pharmacologic, nutritional, and physical exercise guidelines for preserving physical and mental health into old age.This book collects up-to-date information from internationally renowned experts in various biologic fields using physiology as the unifying concept. Illustrated with numerous tables and graphs, Physiological Basis of Aging and Geriatrics, Third Edition focuses on the established facts of physiological aging to provide an essential reference book for a wide spectrum of readers with different levels of biological and educational backgrounds.

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Editorial Reviews

From The Critics
Reviewer: David O. Staats, MD(University of Oklahoma Health Sciences Center)
Description: This is the fourth edition of a multiauthored book on aging and geriatrics. The previous edition was published in 2003.
Purpose: The purpose is to summarize information about aging and longevity, discuss how organ systems change with age, and describe the common diseases of older persons.
Audience: The book is intended for an educated lay audience. Those with a background in biology can understand this book in full. The authors are recognized experts in the field.
Features: The wide range of topics provides an overarching view of the biological and medical aspects of aging, longevity, and diseases in older persons. The chapters are carefully edited. Beautiful diagrams and illustrations complement the text. The references are well chosen and annotated.
Assessment: The careful writing and supporting materials make this revised edition a welcome addition to the field, especially for students contemplating the nature of aging, its physiology, and common diseases in older persons.
H. Bruce Bosmann
The book describes the physiology of aging and physiological events accompanying aging. It is an important book that describes molecular and cellular aging, systemic and organismic aging, prevention and rehabilitation, and general theories of gerontology and aging. The purpose is to describe events and mechanisms of aging particularly from a physiologic and descriptive perspective. This is a large undertaking, and this second edition covers a wide array of topics on the physiology of geriatrics and gerontology. The book is written for a broad spectrum of individuals with varying biological backgrounds. It would be most useful for postbaccalaureate physiologists, geriatricians, or gerontologists. It is written at a graduate student, resident, faculty level and contains a host of graphs and figures giving considerable original data. The book would also be suitable for a researcher who wanted an introductory or starting point for physiologic research in aging. It contains excellent illustrations, figures, and data. One difficulty, however, is that although references to very current data are given, this results in more of an updating than an integration; many references from 1988-1994 are not included. Unique to the book are a large number of very helpful summary diagrams chock full of data. This book is the benchmark text in the field. The second edition is disappointing only in the fact that it is more of an updating than an integration of new data, advances, and ideas since 1988. Also, there is a notable lack of molecular biology and molecular genetics in some areas. However, these shortcomings are minor, and the book deserves to be on appropriate shelves as the definitive text in thisarea.
Doody's Review Service
Reviewer: H. Bruce Bosmann, PhD (University of Illinois at Chicago College of Medicine)
Description: The book describes the physiology of aging and physiological events accompanying aging. It is an important book that describes molecular and cellular aging, systemic and organismic aging, prevention and rehabilitation, and general theories of gerontology and aging.
Purpose: The purpose is to describe events and mechanisms of aging particularly from a physiologic and descriptive perspective. This is a large undertaking, and this second edition covers a wide array of topics on the physiology of geriatrics and gerontology.
Audience: The book is written for a broad spectrum of individuals with varying biological backgrounds. It would be most useful for postbaccalaureate physiologists, geriatricians, or gerontologists. It is written at a graduate student, resident, faculty level and contains a host of graphs and figures giving considerable original data. The book would also be suitable for a researcher who wanted an introductory or starting point for physiologic research in aging.
Features: It contains excellent illustrations, figures, and data. One difficulty, however, is that although references to very current data are given, this results in more of an updating than an integration; many references from 1988-1994 are not included. Unique to the book are a large number of very helpful summary diagrams chock full of data.
Assessment: This book is the benchmark text in the field. The second edition is disappointing only in the fact that it is more of an updating than an integration of new data, advances, and ideas since 1988. Also, there is a notable lack of molecular biology and molecular genetics in some areas. However, these shortcomings are minor, and the book deserves to be on appropriate shelves as the definitive text in this area.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780849373053
  • Publisher: Taylor & Francis
  • Publication date: 8/15/2007
  • Edition description: REV
  • Edition number: 4
  • Pages: 536
  • Product dimensions: 8.50 (w) x 11.00 (h) x 1.00 (d)

Table of Contents

Part I General Perspectives. Old Age as a Stage of Life: Common Terms Related to Aging and Methods Used to Study Aging. Human Longevity in Historical Perspective. Comparative Aging, Geriatric Functional Assessment, Aging, and Disease. Cellular Senescence, Cell Death, and Transgenic Mouse Models of Aging. Theories of Life Span and Aging Part II Systemic and Organismic Aging.. The Nervous System: Structural, Biochemical, Metabolic, and Circulatory Changes. The Nervous System: Functional Changes with Aging. Sensory Systems: Normal Aging, Disorders, and Treatments of Vision and Hearing in Humans. The Adrenals and Pituitary, Stress, Adaptation, and Longevity. Female Reproductive Aging and Menopause. The Ensemble Male Hypothalamo-Pituitary-Gonadal Axis. The Thyroid, Parathyroid, and Pineal Glands. The Endocrine Pancreas, Obesity, and Diffuse Endocrine and Chemical Mediators. The Immune System. Cardiovascular Alterations with Aging: Atherosclerosis and Coronary Heart Disease. Lipids, Lipoproteins, and Atherosclerosis., The Pulmonary Respiratory System: Hematopoiesis and Erythrocytes, The Kidney, the Lower Urinary Tract, Body Fluids, and the Prostate. The Gastrointestinal Tract and the Liver. The Skeleton, Joints, and Skeletal and Cardiac Muscles. The Skin. Part III Prevention and Rehabilitation. Pharmacology and Drug Management in the Elderly. Healthful Aging: Nutrition and Experimental Strategies in Dietary Restriction. Benefits of Physical Exercise. Regenerative Perspectives and Assistive Technologies.

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