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"The eighth edition of this best-selling paperback includes both generic and brand names, overdose and addiction potentials, alcohol-free and sugar-free medicines, usual dosages, side effects, and much more."
Generic Name Abacavir (uh-BAK-uh-veer)
Brand Name Ziagen
Combination Product Generic Ingredients: Abacavir + Lamivudine Epzicom
Type of Drug Antiviral.
Prescribed For Human immunodeficiency virus (HIV) infection.
General Information Abacavir is a man-made nucleoside drug that inhibits the reproduction of the HIV virus. Once inside the HIV-infected cell, abacavir is transformed by enzymes into carbovir triphosphate. Carbovir triphosphate interferes with the activity of HIV reverse transcriptase, an enzyme essential to the virus’ ability to reproduce. Abacavir is always given with another anti-HIV antiviral–such as didanosine, lamivudine, stavudine or zalcitabine–to achieve optimum effectiveness.
Some of the drug is broken down in the liver, some passes out of the body unchanged in the urine, and some passes out of the body in the stool.
Cautions and Warnings Stop taking this drug at the first sign of drug allergy or sensitivity (see “Special Information”). People have died from abacavir sensitivity.
People with liver disease should be cautious about using this drug because of the possibility that it can aggravate the condition. Some people have died from liver damage associated with abacavir.
The use of nucleoside drugs such as abacavir can very rarely cause lactic acidosis, a fatal metabolic disturbance.
Resistance to abacavir has developed in laboratory versions of HIV also resistant to lamivudine, didanosine, and zalcitabine. HIV that is resistant to protease inhibitors is not likely to be resistant to abacavir.
Redistribution or accumulation of body fat may occur in people taking antiviral medications including: central obesity; facial, arm, leg, and/or buttock wasting; breast enlargement; and fat accumulation at the base of the neck (buffalo hump).
Abacavir cannot be used in infants under age 3 months.
• Alcohol interferes with the elimination of abacavir through the liver and can lead to a 40% increase in the amount of drug in the blood.
• Abacavir can increase blood levels of acetaminophen, amitriptyline, bumetanide, chloral hydrate, chlorpheniramine, chlorpromazine, chlorzoxazone, dapsone, doxepin, fluconazole, imipramine, ketoconazole, labetalol, lamotrigine, miconazole, morphine, naloxone, non-steroidal anti-inflammatory drugs (NSAIDs), oxazepam, promethazine, propofol, propranolol, and valproic acid.
• Cigarette smoking and clofibrate may reduce the amount of abacavir in the blood.
• Combining abacavir with isoniazid may decrease abacavir levels and increase isoniazid levels in the blood.
• Abacavir levels in the blood may be decreased if you are also taking phenobarbital, phenytoin, or T3 thyroid hormone replacement.
• Abacavir may increase the speed with which methadone is cleared from the body. Changes in methadone dose are usually not required.
For further drug interactions for Epzicom, see Lamivudine, page 611.
Food Interactions None known.
Usual Dose Adult (age 17 and over): 300 mg 2 times a day.
Child (age 3 months—16 years): 3.6 mg per lb. of body weight twice a day, up to a maximum of 300 mg in each dose.
Overdosage Little is known about the effects of abacavir overdose. Overdose victims should be taken to a hospital emergency room for treatment. ALWAYS bring the prescription bottle or container.
Special Information Stop taking this drug and call your doctor at the first sign of allergy or sensitivity. Symptoms include fever, rash, fatigue, nausea, vomiting, diarrhea, abdominal pain, sore throat, difficulty breathing, and coughing. Some patients who experienced a hypersensitivity reaction were initially thought to have a respiratory infection. If you continue to take abacavir and are allergic to it, more severe reactions including a life-threatening drop in blood pressure could develop in hours.
Abacavir is not a cure for HIV. People taking the drug may still develop opportunistic infections and other conditions associated with HIV infection. People taking abacavir can still be infectious and transmit HIV to others.
The long-term effects of abacavir are not known. Report anything unusual to your doctor.
It is very important for you to take abacavir exactly as prescribed. If you forget to take a dose and remember within 2 to 3 hours, take the medication. If you forget until it is almost time for your next dose, skip the forgotten dose and continue with your regular schedule. Remember, every dose of any HIV medication you forget or skip can make it more difficult for the drugs to do their job and can also lead to the development of HIV resistant to abacavir.
Pregnancy/Breast-feeding: Abacavir passes into the fetal circulation. In animal studies, the drug caused low birth weight and increased the risk of stillbirth. The effect of abacavir in pregnant women is not known. When this drug is considered crucial by your doctor, its potential benefits must be carefully weighed against its risks.
It is not known if abacavir passes into breast milk. Women with HIV are advised to bottle-feed their babies to avoid transmitting the virus.
Seniors: Studies of abacavir did not include many seniors. Seniors should use this drug with caution because of the risk that normal reductions in organ function or drug interactions may affect how abacavir works in the body or increase the likelihood of side effects.
Generic Name Acamprosate (ah-CAM-pro-sate)
Brand Name Campral
Type of Drug Synthetic neurochemical similar to the amino acid homotaurine.
Prescribed For Alcoholism.
General Information Acamprosate is used to help alcoholic patients stay alcohol-free after they have stopped drinking. Unlike other drugs used to help people stay away from alcohol, it does not cause people to have a physical reaction to alcohol.
Acamprosate restores the balance between two chemical systems in the brain, glutamate and GABA, that are known to become unbalanced in alcoholics, but its exact action is not known. It may reduce alcohol craving.
Acamprosate should be part of a program that includes counseling and support, and it should be started as soon as possible after alcohol withdrawal and continued even if the patient starts drinking again. This medication has not been proven to help patients if they are still drinking when they start treatment. Acamprosate has not been studied in patients who abuse other substances together with alcohol. Tolerance or addiction has not developed with acamprosate. It passes out of the body through the kidneys.
Cautions and Warnings Do not take acamprosate if you are allergic or sensitive to any of its ingredients or if you have severe kidney disease.
People with moderate kidney disease require a lower dosage of acamprosate.
Acamprosate does not eliminate or ease alcohol withdrawal symptoms.
People taking acamprosate may become depressed or have suicidal thoughts.
Acamprosate can affect your judgment, thinking, or coordination. Do not drive or operate dangerous machinery if you are taking this medicine.
• Mixing acamprosate with naltrexone can increase the levels of both drugs in the blood, but no dose adjustments are needed.
Food Interactions Acamprosate may be taken without regard to food or meals.
Usual Dose Adult: Two 333-mg tablets 3 times a day.
Child: not recommended.
Overdosage The only symptom associated with acamprosate overdose has been diarrhea. Overdose victims should be taken to a hospital emergency room for observation and treatment. ALWAYS bring the prescription bottle or container.
Call your doctor if you are breast-feeding, pregnant, or thinking about becoming pregnant while taking this medicine.
Take care while driving a car or performing complex tasks.
If you forget to take a dose, take it as soon as possible. If you do not remember until it is almost time for your next dose, skip the dose you forgot and continue with your regular schedule. Call your doctor if you forget to take 2 or more doses in a row. Do not take a double dose.
Acamprosate must be part of an ongoing treatment program. Do not stop taking it on your own, even if you start drinking again.
Pregnancy/Breast-feeding: Acamprosate can damage animal fetuses in doses that are approximately equal to those taken by people on this medicine. Women of childbearing age should use an effective contraceptive while taking this drug. The potential benefits of acamprosate must be weighed against its risks if your doctor considers it a crucial treatment during your pregnancy.
Acamprosate passes into breast milk. Nursing mothers who must take this drug should bottle-feed.
Seniors: Dosage reduction may be needed in seniors because of a general decline in kidney function due to age.
Generic Name Acarbose (uh-CAR-bose)
Brand Name Precose Type of Drug Antidiabetic.
Prescribed For Type 2 (non-insulin-dependent) diabetes mellitus.
Posted September 6, 2009
If you are looking for a quick reference guide to the most common drugs and pills on the market today, The Pill Book (13th Edition) by Harold M. Silverman is the book for you. While certainly less comprehensive (and less expensive) than a Physicians' Desk Reference Guide, it does give the names, types of drugs, general information, warnings, dosages, and drug interactions for the most commonly prescribed drugs on the market in the United States, as well as what conditions these drugs are prescribed for. It comes in a matter-of-fact format and is easy for the average layperson to use.
5 out of 5 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted August 1, 2010
I purchased this book for my nook and that was a mistake. It is very difficult to find what you're looking for even if the medication is listed in alphabetical order. I would roll pass it one way or the other and it takes forever to find by clicking one page at a time. I finally just gave up, as I was trying to research 5 medications, and decided to try again later when I cooled down. An index would have been nice even if the page referenced differed by 3 or 4 pages. Very poor purchase, buy the book not the e-book.
4 out of 5 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted February 18, 2005
Believe me when I say that this book is very easy to digest. It is exactly what the title infers- a big book that explains just about every pill you can imagine (and it is a pretty thick book indeed). A poor man's PDR, but just as useful, I recommend it to anybody that wants a good reference for medications.
3 out of 3 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted February 20, 2010
Posted March 8, 2001
when I get a prescription. They don't say much about drug interactions, or what to do when I've missed a dose. They often assume I know technical jargon like 'MAO Inhibitor' or 'Tricyclic Antidepressant'. Clearly they were written by scientists for--well, not for scientists but probably for the drug companies and pharmacists to relieve themselves of liability in case of misuse. Do yourself a favor and get ahold of the pill-takers' 'Bible'--this one truly is. Any family that gets more than one prescription filled a year can benefit from THE PILL BOOK. This book does its best to describe, thoroughly and patiently, the ins and outs of every prescription drug in America, what the drug is meant to do, the side effects, interactions, who should not be taking it, whether generics are available, what to do if abused, if you miss a dose, and so on. There are even color plates of the most widely prescribed drugs. Who knows? This book might even save your life; it certainly has saved me money and time.
2 out of 2 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted December 5, 2014
Don't buy the nook version. It doesn't have visuals so you can't even identify the pills. Not to mention it doesn't have them all like it says. So, if you're going to get this, get the real version, not the NOOK version. ):(
1 out of 1 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted July 27, 2010
Posted December 2, 2004
I've used this book off and on and sometimes its hit and miss for the drugs I need to lookup but the title of the book is MOST-PRESCRIBED not ALL prescription drugs apparently the other reviwers fail to realize that a book having every single drug would cost much more than $6.99.
1 out of 2 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted June 9, 2004
I purchased this book to educate myself on any medications that my family is taking. It was ok at first for general ailments but my husband was diagnosed with a potentially life threatening condition and I can't find any of the newer drugs that have been prescribed for him. I went to the Doctor for an ear infection and The Pill Book does not have the drops my physician told me to take. Today's antibiotic resistant bacterias require that new medicines be formulated. The Pill Book is not keeping up with technology.
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Posted February 1, 2013
This is the one book that every household should have. With the fast & continuous introduction of new drugs to the market this book lets you know exactly what you are taking.
Informative and in layman's terms this book is a must!
Posted October 12, 2012
I have used every "Nook-trick" that I can think of to get this book to open. It just will not open. I'm seriously thinking of just deleting the whole thing AFTER I call B & N to get my credit on this. I really think I'd rather buy it at the pharmacy anyway. The real deal is way easier to highlight and mark! Thumbs down on this one!Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted July 10, 2012
Don't buy for NOOK.
The print copy is still the best pill research handbook out there but the NOOK version is a head scratcher. There is no index, just "chapter" links and no way to quickly look at or up information. It's a horrible format, and the color plates are small scans at the end. Very clumsy and difficult on NOOK, worthless, really.
Posted October 21, 2010
Posted April 28, 2009
I bought this for a very good friend of mine, so I can't give my direct opinion of this reference book, however, she stated that it was more complicated to follow than publications which she had purchased prior.
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Posted February 16, 2007
I'm an MD and a pharmacologist and have never heard of Harold Silverman but it seems this book doesn't follow evidence-based medicine. Perhaps a good medical editor with knowledge of how drugs should be used in medical practice could help.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted November 16, 2003
Well, i bought this book six month ago, and the book did mention some of the drup i'm using for certain ailment. however, this pill book need a major update and added more source of prescription name in it. In addition, this book need more picture of certion type of drup like prozact, and seperate them from brand name to generic. if want to buy this book, then you should have it. You should alway update your pill book, for treatment, a cure, or for a thirst of knowledge about certain type of drugs.
0 out of 1 people found this review helpful.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted June 16, 2003
I bought this book because I am on quite a few different medications for the illness I have. I can't find but a few of the medications I'm on in this book. I was very disappointed. The medications are not new and they are far from being rare. Sorry, but very disappointing to me.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted September 13, 2002
I have been using the Pillbook through several editions. I first began reading the book, and using it religiously, when I lived in Connecticut in 1987. My (then) husband was given a prescription for some type of medication (I can't remember the name of it right this minute, and hesitate to use what I think it is, in case I didn't remember correctly). However, it was prescribed for him after he had herniated a disc in his lower back, (and I'm sure workers comp wanted him back to work quickly)and we filled the prescription, and I picked up or already had in my possession a copy of The Pillbook. I was extremely surprised to read, that the extremely educated and good doctors of the Hartford area, did not inform my husband that if he abruptly stopped taking this drug that he might have a heart attack. Needless to say, he decided that it wasn't in his best interest to use this medication, as he is not in the habit of using any medication unless it is absolutely necessary, and much like myself, would stop taking the medication when the pain wasn't bad enough to need anything more than a Tylenol or an Advil. On more than several occasions, I have found this book extremely helpful when being prescribed this drug or that drug, and asking the doctor if this other drug might not do the same thing for me, without either the side-effects or dangers involved... to find out that yes the other medication would do the same thing. My household would not be without a copy of The Pillbook sitting patiently on a shelf, waiting for me to pick it up and use it once again. (Don't laugh, but sometimes I read it just for fun). There was also another book I owned back in 1987 that I found extremely helpful as well. It was some type of medical dictionary, and it again was in layman's terms that was understandable when read. I found it quite helpful in some diagnoses as well. I wish that I could find it once again.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted July 28, 2002
This book provides the consumer with a detailed explanation of the drugs that have been perscribed to them, while keeping the terminology simple enough for everyone to understand. There is also a visual reference to help you ensure you are taking the correct medications. I would strongly suggest this book.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.
Posted April 30, 2002
It has all the newest medications and it gives you the symptons and it's purpose. It is compact so you don't have to carry around a bulky medicine book. You can easily take it anywhere. I love this book and it gives me everything I need to know.Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.