Plasmonic Nanobubbles: From Physics to Clinics

by Dmitri Lapotko

Overview

This book delves into the transformative potential of external energy in diagnosing and treating diseases, ranging from cancers to malaria, at their core. The strategy is to replace often harmful substances in patients with on-demand diagnostic and therapeutic events in cells. By merging physics, nanotechnology, and biology, laser pulses are converted into tiny explosions, named plasmonic nanobubbles, within cells. By harnessing disease to create energy-converting structures, plasmonic nanobubbles deliver precise diagnostic and therapeutic effects that improve traditional medicine. Their real-time nature supports robotics and artificial intelligence to create cell-level medicine of the future. For instance, plasmonic nanobubbles instantly detect and destroy aggressive cancer cells or malaria parasites that are otherwise undetectable. This book is the first comprehensive resource for understanding plasmonic nanobubble concepts, experiments, and clinical designs in non-invasive diagnostics, biopsy, endoscopy, microsurgery, drug and gene delivery, and therapy.

Product Details

ISBN-13:	9789815129076
Publisher:	Jenny Stanford Publishing
Publication date:	02/21/2025
Pages:	1180
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Dmitri Lapotko obtained his PhD in laser physics from Belarus State University and Doctor of Science in bioengineering from A. V. Lykov Heat and Mass Transfer Institute, Belarus. His research in physics, biophotonics, and nanotechnology resulted in the invention of the non-stationary photothermal platform which converts the external energy into precise nano-events such as plasmonic nanobubbles, with multiple medical applications.

Table of Contents

Introduction

1. Physical Principles and Properties of Plasmonic Nanobubbles

2. Biomedical Mechanisms of Plasmonic Nanobubbles

3. Photothermal Vapor Nano- and Microbubbles around Endogenous Chromophores and Optically Absorbing Dyes

4. Clinical Applications of Laser Pulse-Activated Vapor Nanobubbles: Methods and Technologies

 

Editorial Reviews

We are still at an early stage in understanding the potential biomedical applications of the relatively new science of nanotechnology. For years, Dimitri Lapotko has been a pioneer in the exciting field of plasmonic nanobubbles and how this new technology might alter the ways we diagnose and treat human illnesses. In his new book, appropriately titled, Plasmonic Nanobubbles: From Physics to Clinics, he details how this approach has exciting applications for a diverse set of conditions ranging from malaria to cancer. He gives us a unique vision on how the study of physics could one day revolutionize modern medicine.”

Dr Peter Hotez

Texas Children’s Hospital, USA; Baylor College of Medicine, USA; Rice University, USA

 

“The goal of treating any disease, especially cancer, is to detect and destroy abnormal cells while leaving normal cells undisturbed. In this book, Dmitri Lapotko presents a multidisciplinary combination of physics and physiology expertise in using plasmonic nanoparticles that can adsorb picosecond laser pulses to deliver drugs, detect pathogens, or destroy specific cells by generating exploding nanobubbles with sub-micron precision. This is an essential text for any clinician or researcher interested in pushing the boundaries of localized and specific therapies.”

Dr Joseph A. Zasadzinski

University of Minnesota, USA

 

“In his book, Dmitri Lapotko shows a novel strategy to convert laser energy into diagnostic, surgical, and therapeutic events in patients with cell-level precision. The book describes the universal physical-biological mechanism of laser pulse-generated events, plasmonic nanobubbles. This book, rich with practical experimental and engineering solutions and examples, will help the next generations of researchers and engineers to further advance laser technologies into clinics.”

Dr Hans A. Schuessler

Texas A&M University, USA

 

From the Publisher