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Elyssa East
The Poisoner's Handbook is an inventive history that, like arsenic mixed into blackberry pie, goes down with ease.—The New York Times
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Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie" (The New York Observer)
A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice.
From Sarah Weinman's "THE CRIMINALIST" column on Barnes & Noble Review
Murder provides the crux for a good many of the stories which fascinate us, whether the tale comes from the tabloids or a novelist's imagination. But the act itself often eludes narrative. A cloud of rage, a moment of opportunity, and a weapon in hand leads to death in minutes, even seconds, barely enough time to register that the victim has moved out of the land of the living. Add a dash of poison, however, rationed out in small doses over a long period of time, and murder leaves the realm of second-degree impulse for first-degree pre-meditation. Randomize the efforts and, in recent cases like the 1982 Tylenol murders and the 2001 anthrax attacks, the result is domestic terror, the lack of resolution lingering in the air like the bitter almond smell of cyanide.
Contemporary crime fiction's emphasis on verisimilitude and character favors more easily discernible death mechanisms like gunshots, stab wounds and ligatures, in large part because there are more such murders in real life. But the genre's Golden Age, from the turn of the 20th Century to World War II, ran amok with poisoners, whose crimes could be couched as debilitating sickness or the natural run of aging. Once unmasked by the likes of Agatha Christie -- who knew a thing or two about insidious chemicals thanks to an earlier job dispensing pharmaceuticals -- the handiwork of these villains were a testament to elegantly complex plotting and fiendish misdirection of the reader.
These parlor tricks of fiction also reflected what Pulitzer Prize-winning journalist Deborah Blum describes, in her new bookThe Poisoner's Handbook as "a deadly cat and mouse game, [with] scientists and poisoners as intellectual adversaries." Although poison is as old as human culture (think of the death of Socrates) its operation couldn't be understood until the advent of modern chemistry. By the early 1800s it was possible to detect the presence of poison, and by the early 20th Century European toxicologists were staying in step with drug-happy murderers who thought they could get away with their crimes, only to be foiled by post-mortem chemical tests.
In America, these advances ran into somewhat greater obstacles. Forensic science practices were nowhere close to their counterparts across the Atlantic -- American states and towns were riddled with incompetent coroners, underfunded laboratories and indifferent politicians who could not keep pace with the "wealth of modern poisons" created by the innovations of industry. The clever poisoner, however, was about to meet his match in the two heroes of Blum's fascinating account of the dawn of modern American forensic toxicology; The Poisoner's Handbook offers a synthesis of societal forces and chemical advances with barely detectable seams.
On January 31, 1918, years after a scathing report indicted New York City's coroners for falling down on the job and despite endless delays by Tammany Hall-controlled state legislature, Charles Norris, Bellevue Hospital's chief pathologist, was appointed the city's first Chief Medical Examiner. The appointment was a watershed:
It would be imprecise to say that [Norris] loved the job...he lived and breathed it. He spent his own money on it. He gave it power and prominence and wore himself into exhaustion and illness over it. Under [his] direction, the New York City medical examiner's office would become a department that set forensic standards for the rest of the country.
Norris courted the public, which latched on to his "buoyant laugh and quick wit," and had a keen sense of the absurd ("We call this the Country Club," he would tell visitors) but never forgot his objective to overcome, as he described in an essay, "a system which fosters ignorance, prejudice and graft."
His partner in pathological crime, at least on the toxicology front, was Alexander Gettler. Unlike his boss, he didn't care for the media (reporters would grow frustrated at Gettler's tight-lipped answers, one memorably setting him down as "a personality as colorless as the sodium chloride that he works with" but shared a passion for medical research, extremely long hours and, most importantly, for devising new ways to catch previously undetectable culprits. Gettler, in essence, would have to invent the wheel, since New York's toxicology lab was America's first: "If a test didn't exist, he would invent it. If research methods didn't exist, he would develop them himself. If a new poison or drug came on the market, he went off to a butcher shop...and bought three pounds of liver."
Compared to modern machines that detect traces of substances down to parts per billion, Gettler's resources and methods come across as shockingly brute and quaint. But fields must begin somewhere, and Gettler's determination to beat poisoners at their own game forms the emotional core of The Poisoner's Handbook, which is otherwise a marvel of structural and narrative trickery. Each chapter is named for a particular chemical substance with the power to kill, the order carefully chosen to reflect the many balls Blum must juggle throughout: chloroform (CHCl3) and its oh-so-sweet smell kicks things off because it was used by a serial murderer unknown to the collapsing coroner system, while the two chapters bearing the same chemical formula of CH3OH comment on the inexorable but separate rise of cheap, deadly wood alcohol and its twin, synthetic methyl alcohol -- both boosted first by the onset of Prohibition, the set of booze-banning laws that helped define the Jazz Age's penchant for excess, and second by and the national despair brought on by the Great Depression. Not all poisons are elegant, and Blum's necessary emphasis on alcohol poisoning (which zoomed up 600% between 1920 and 1930) acts as a subtle reminder that Wars on Substances of any stripe prove to be more costly, inefficient, and damaging than the drug itself.
Other poisons get their moment as the m.o. of cases famous or forgotten. Cyanide's "murderously precise" action, binding tightly to haemoglobin molecules at the expense of oxygen, spurred Gettler and his liver meat-grinding to prove that an older couple's death in Brooklyn's Hotel Margaret was an accident, not murder. The "chemical thug" carbon monoxide's rise to prominence owed its thanks to the parallel rise in automobile usage, and its detection both fingered murderers and saved innocent men from execution. And the detection of arsenic reverses the fortunes of a poisoned-minded woman named Mary Frances Creighton, who twelve years earlier was acquitted when Gettler's painstaking techniques were mocked in court. It was, for Gettler and Norris, a triumph that "had, indeed, changed the poison game" and commanded respect for forensic toxicology.
Blum's extraordinary narrative alchemy fuses Gettler and Norris's painstaking, laborious undertakings with the birth of safety measures (the Food and Drug Administration wasn't much of one until the 1930s), the scandal surrounding workers' exposure to radium, and many other measures that bring home how volatile the transformation from prosperity to struggle really was. A few things get lost, like what debt both Norris and Gettler owed to colleagues in other cities and countries (Blum, to her credit, makes a note of this in supplementary material) or what clashes they had with law enforcement (though the ones with government are well-documented.) But these flaws don't diminish The Poisoner's Handbook's glorious depictions of the "coming-of-age party for forensic toxicology." The book is an unexpected yet appropriate open-sesame into a world that was planting seeds for the world -- with lethal toxins and cutting-edge tools -- that would later, darkly bloom.
PROLOGUE
THE POISON GAME
Until the early nineteenth century few tools existed to detect a toxic substance in a corpse. Sometimes investigators deduced poison from the violent sickness that preceded death, or built a case by feeding animals a victim's last meal, but more often than not poisoners walked free. As a result murder by poison flourished. It became so common in eliminating perceived difficulties, such as a wealthy parent who stayed alive too long, that the French nicknamed the metallic element arsenic poudre de succession, the inheritance powder.
The chemical revolution of the 1800s changed the relative ease of such killings. Scientists learned to isolate and identify the basic elements and the chemical compounds that define life on Earth, gradually building a catalog, The Periodic Table of the Elements. In 1804, the elements palladium, cerium, iridium, osmium, and rhodium were discovered; potassium and sodium were isolated in 1807; barium, calcium, magnesium, and strontium in 1808; chlorine in 1810. Once researchers understood individual elements they went on to study them in combination, examining how elements bonded to create exotic compounds and familiar substances, such as the sodiumchlorine combination that creates basic table salt (NaCl).
The pioneering scientists who worked in elemental chemistry weren't thinking about poisons in particular. But others were. In 1814, in the midst of this blaze of discovery, the Spanish chemist Mathieu Orfila published a treatise on poisons and their detection, the first book of its kind. Orfila suspected that metallic poisons like arsenic might be the easiest to detect in the body's tissues and pushed his research in that direction. By the late 1830s the first test for isolating arsenic had been developed. Within a decade more reliable tests had been devised and were being used successfully in criminal prosecutions.
But the very science that made it possible to identify the old poisons, like arsenic, also made available a lethal array of new ones. Morphine was isolated in 1804, the same year that palladium was discovered. In 1819 strychnine was extracted from the seeds of the Asian vomit button tree (Strychnos nux vomica). The lethal compound coniine was isolated from hemlock the same year. Chemists neatly extracted nicotine from tobacco leaves in 1828. Aconitine— described by one toxicologist as "in its pure state, perhaps the most potent poison known"— was found in the beautifully flowering monkshood plant in 1832.
And although researchers had learned to isolate these alkaloids— organic (carbon-based) compounds with some nitrogen mixed in— they had no idea how to find such poisons in human tissue. Orfila himself, conducting one failed attempt after another, worried that it was an impossible task. One exasperated French prosecutor, during a mid-nineteenth-century trial involving a morphine murder, exclaimed: "Henceforth let us tell would be poisoners; do not use metallic poisons for they leave traces. Use plant poisons… Fear nothing; your crime will go unpunished. There is no corpus delecti [physical evidence] for it cannot be found."
So began a deadly cat and mouse game—scientists and poisoners as intellectual adversaries. A gun may be fired in a flash of anger, a rock carelessly hurled, a shovel swung in sudden fury, but a homicidal poisoning requires a calculating intelligence. Unsurprisingly, then, when metallic poisons, such as arsenic, became detectable in bodies, informed killers turned away from them. A survey of poison prosecutions in Britain found that, by the mid- nineteenth century, arsenic killings were decreasing. The trickier plant alkaloids were by then more popular among murderers.
In response, scientists increased their efforts to capture alkaloids in human tissue. Finally, in 1860, a reclusive and single-minded French chemist, Jean Servais Stas, figured out how to isolate nicotine, an alkaloid of the tobacco plant, from a corpse. Other plant poisons soon became more accessible and chemists were able to offer new assistance to criminal investigations. The field of toxicology was becoming something to be reckoned with, especially in Europe.
The knowledge, and the scientific determination, spread across the Atlantic to the United States. The 1896 book Medical Jurisprudence, Forensic Medicine and Toxicology, cowritten by a New York research chemist and a law professor, documented the still-fierce competition between scientists and killers. In one remarkable case in New York, a physician had killed his wife with morphine and then put belladonna drops into her eyes to counter the telltale contraction of her pupils. He was convicted only after Columbia University chemist Rudolph Witthaus, one of the authors of the 1896 text, demonstrated the process to the jury by killing a cat in the courtroom using the same gruesome technique. There was as much showmanship as science, Witthaus admitted; toxicology remained a primitive field of research filled with "questions still unanswerable."
I'm a biology major who is wanting to work in the field of forensics, and I'm a bit of a history buff, too. So, this book was right up my alley. It was informative without being dry. People unfamiliar with chemistry should have no problem understanding it, but some of the descriptions of the chemistry of the poisons might get tedious. I found the case studies and personal anecdotes very interesting. If you enjoyed Mary Roach's "Stiff", you will probably enjoy this one as well.
3 out of 3 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.JcDean
Posted November 11, 2010
I've already bought this book for myself, and after starting it, I could not put it down! It was so fascinating, I ended up buying two more copies for friends, and they also found it equally fascinating. Nonfiction that reads like fiction. I will keep my eye out for future Deborah Blum books!
2 out of 2 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.To all the fans of CSI, NCIS, etc., read this book! If you want to see what forensic criminology was like "back in the day" you could not choose a better book. The history of this subject is largely ignored by the popular press and it is fascinating (if a bit stomach-churning on occasion).
I finished it in 3 days! And it left me wanting more, more information, more stories. The author did her subject proud.
2 out of 3 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Anonymous
Posted January 13, 2013
The story is based in New York City in the early 1900's. It was the time of prohibition, and the beginning of what you could call a medical revolution. Mercury, cyanide, chloroform, wood alcohol, and more, stocked doctors' offices, homes, and pharmacies. With the beginning of Prohibition, each cocktail drank added to a game of chance.
. The people of New York City knew something had to change, so pathologist Charles Norris was hired. Norris along with with chemist Alexander Gettler, founded the city's first toxicology laboratory. The main story though, starts before Gettler and Norris. It starts when an unlikely killer springs up and bares its nasty fangs.
. This story is very believable and exciting. For people who enjoy television shows like CSI or NCIS, this book gives you a perfect combination of chemistry and forensics.
. Norris, Gettler, and other characters in the story are all believable. I want to know why Charles Norris chose to become a pathologist, and why he wanted Gettler so badly on his team.
. The science content is very accurate. I wouldn't necessarily want to learn more about the poisons, but I would be interested in learning more about the pathology and medical side to the story.
. In my opinion, this book is for somebody who is interested in chemistry more than anything. It was an ok book, but probably not one I would choose to re-read.
.
1 out of 2 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.LAT72
Posted June 16, 2011
Now I know just enough about poisons to be dangerous, I definitely want to learn more. Blum has put together a well-researched and interesting look at Jazz Age New York....from an unexpected angle.
1 out of 1 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Nigai
Posted February 5, 2011
Authoratative and exceptionally well written? Ms Blum makes the 1920's come alive. She gives historians an excellent background as to why the 18th amendment failed and the government's ghastly hand in poisoning those people who just had to drink. Despite the politics of the time, she also brings to hand the hard work of Doctors Norris and Gettler. The state of forensic pathology is still catching up to Europe.
1 out of 1 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Loved it! I love reading non-fiction and learning new things. I learned a great deal from this book. At times, the science talk was a little too much but over all it was easy to understand and I couldn't put it down! I just wish it had pictures!
1 out of 1 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Anonymous
Posted April 10, 2010
I found this book to be riveting; it explains the history of different poisons. Far from being macabe, as it may first sound, it is a history lesson of how poisons came into use and how forensic medicine began to detect these substances.
1 out of 1 people found this review helpful.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Anonymous
Posted February 1, 2013
I'd been wanting to get this book for a while, and finally did. It's a great read - an interesting history book, with science tied in, and pretty easy and entertaining as well. I'm almost done with it, and will be sad when it's over. I would definitely recommend it.
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Posted January 28, 2013
An excellent historical account about early forensic science.
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Posted January 4, 2013
Since I'm not a chemist, I knocked off a star from five to four because some of the text is chemistry, which I do not understand, but, other than that, this is one heck of a good read. It explains the culture going on in the 1920's, from an informed, statistics point of view. Not dry (pun intended) as I would have expected from a science writer. Poor people were being murdered in alarming numbers, all to save the facade of the movement of Prohibition. More were being poisoned by ignorance of the day of the complex physics of natural gas. The American government was responsible for so many murders and accidental deaths! Many courageous scientists sacrificed their careers in the name of saving untold lives. We all owe them a debt of gratitude.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.iankh
Posted December 28, 2012
The Poisoner's Handbook, while non-fiction reads like fiction. It has a great narrative and takes us into an interesting time, the Jazz Age. We're at the point in our culture where Prohibition has come in and toxicology and forensics are starting to emerge in their own right. Deborah Blum does an excellent job in weaving together science and history. It also made me appreciate how far we've come and how things we take for granted, such as toxic ingredients not being added to food and drugs, wasn't always so. I recommend this work to anyone interested in this period.
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Posted December 19, 2012
Very imteresting well writtem reads like a novel-
I choice it for book club, most of us gave it 5 stars
If history or science interest you at all or u watch CSI, I highly recomamd this book
Anonymous
Posted December 17, 2012
This is such a wonderfully weird, informative book. What could have been a dry read about the history of forensic science was a real page turner. The author intersperses scientific facts with human stories that highlight the social and emotional consequences of deliberate and unintentional poisoning, advancing forensic work, prohibition, and poverty to name a few.
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Posted December 12, 2012
good
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Anonymous
Posted October 22, 2012
I learned a lot more about the beginning of forensic science. I also learned more about the 1920s reading this book .
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Posted October 14, 2012
Poisoner's Handbook is fascinating and well written. For a book about chemestry, it reads like a crime novel. I couldn't put it down. Fans of Mary Roach will love Debora Blum.
RossBlocher
Posted April 3, 2012
I've been thoroughly enjoying this expose on the various forms of lethal chemicals that have been used throughout the ages. Deborah Blum deftly balances the stories of deaths and murders, the science behind how the chemicals kill, and the race by toxicologists to keep up with detection of the advancing poisoning techniques. You'll learn a lot that will come in handy for future conversations.
Was this review helpful? Yes NoThank you for your feedback. Report this reviewThank you, this review has been flagged.Anonymous
Posted January 16, 2012
Blum shows perfectly balanced writing skills by blending intricate science details with engaging storytellling. The amount of research is impressive. While reading "Handbook" a second time I kept imagining who I would want to see play these characters in a movie. The story of these forensic pioneers should be known to everyone.
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Posted January 6, 2012
I just finished this book in two days, it was such a page-turner! I loved how the author managed to evoke the creepy and sinister atmosphere around the times, places, and people she wrote about. I also have a new respect for early forensic pioneers. A deft mix of history, science, and criminal mysrery with a dash of the deliciously ghoulish.
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Overview
Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie" (The New York Observer)
A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany ...