Polycystic Kidney Disease / Edition 1

Polycystic Kidney Disease / Edition 1

by Torres Watson, Michael L. Watson, Vicente E. Torres
     
 

ISBN-10: 0192625780

ISBN-13: 9780192625786

Pub. Date: 07/28/1996

Publisher: Oxford University Press, USA

Many inherited diseases and non-herediatry disorders have in common the development of renal cyctic disease. The most common, autosonal dominant polycystic kidney disease, is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation.
Since the publication six years ago of the last book on polycystic kidney disease, a number of genes

Overview

Many inherited diseases and non-herediatry disorders have in common the development of renal cyctic disease. The most common, autosonal dominant polycystic kidney disease, is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation.
Since the publication six years ago of the last book on polycystic kidney disease, a number of genes causing the disease have been identified, mapped, or sequenced; new experimental models and the application of molecular biology techniques have provided new insights into the pathogenesis of polycystic kidney disease; novel clinical studies have provided valuable information for the prevention, evaluation, and treatment of the complications of this disease. This book provides an updated, state-of-the-art review of the genetics, pathophysiology, evaluation, and management of these diseases and will be of interest to both basic researchers and clinicians in nephrology.

Product Details

ISBN-13:
9780192625786
Publisher:
Oxford University Press, USA
Publication date:
07/28/1996
Series:
Oxford Clinical Nephrology Series
Edition description:
New Edition
Pages:
608
Product dimensions:
8.81(w) x 9.75(h) x 1.49(d)

Table of Contents

Part I: Cystic renal disease: experimental models and pathology
1. Principles of molecular biology as applied to the study of disease
2. In vitro models in the study of renal cystogenesis
3. Mouse models of polycystic kidney disease
4. In vivo models in non-murine species
5. Pathogenesis of polycystic kidney disease: basement membrane and extracellular matric
6. Pathogenesis of polycystic kidney disease: altered cellular function
Part II: Cystic renal disease: clinical spectrum
7. Classification of cystic kidneys
8. Diagnostic imaging of renal cystic diseases
9. Autosomal recessive polycystic kidney disease: clinical and gentic profiles
10. Acquired renal cystic disease
11. Tuberous sclerosis
complex
12. Von Hippel-Lindau Disease
Part III: Adult polycystic kidney disease: natural history and genetics
13. Definition and natural history of autosomal dominant polycystic kidney disease
14. Cloning strategies and genetics of type 1 autosomal dominant polycystic kidney disease
Part IV: Adult polycystic kidney disease: clinical features
16. Hypertension in polycystic kidney disease
17. Progression to renal insufficiency
18. Management of end-stage renal failure and problems of transplantation in autosomal dominant polycystic kidney disease
19. Chronic pain and its medical and surgical management in renal cystic disease
Part V: Adult polycystic kidney disease: complications
20. Miscellaneous renal and systemic complications of autosomal dominant polycystic kidney disease including infection
21. Polycystic liver disease
22. Intracranial aneurysms in autosomal dominant polycystic kidney disease
23. Particular problems in childhood and adolescents in autosomal dominant polycystic kidney disease
24. Counselling and ethical considerations in autosomal polycystic kidney disease

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