Positron Emission Tomography: Basic Sciences / Edition 1

by Dale L. Bailey, David W. Townsend, Peter E. Valk, Michael N. Maisey

Overview

Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable.

This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters:

• 2 new (chapters 1, 16)
• 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18)
• 3 minor corrections (chapters 2, 6, 11)
• 5 unchanged (chapters 3, 7, 9, 10, 12)

Product Details

ISBN-13:	9781852334857
Publisher:	Springer London
Publication date:	05/12/2003
Edition description:	2003
Pages:	382
Product dimensions:	8.50(w) x 10.98(h) x 0.08(d)

Table of Contents

Positron Emission Tomography in Clinical Medicine.- Physics and Instrumentation in PET.- Data Acquisition and Performance Characterization in PET.- Image Reconstruction Algorithms in PET.- Quantitative Techniques in PET.- Tracer Kinetic Modeling in PET.- Coregistration of Structural and Functional Images.- Anato-Molecular Imaging: Combining Structure and Function.- Radiohalogens for PET Imaging.- Progress in 11C Radiochemistry.- Metal Radionuclides for PET Imaging.- Radiation Dosimetry and Protection in PET.- Whole-Body PET Imaging Methods.- Artefacts and Normal Variants in Whole-Body PET and PET/CT Imaging.- The Technologist’s Perspective.- PET Imaging in Oncology.- The Use of Positron Emission Tomography in Drug Discovery and Development.- PET as a Tool in Multimodality Imaging of Gene Expression and Therapy.

Editorial Reviews

From the reviews:

It is, simply put, the best work I have encountered on the "non-clinical" aspects of the important field of PET. The scientific features are explained clearly at all levels and are well illustrated so that the treatment will suit both experts in physics and radiochemistry and newcomers hoping to understand and perhaps use the techniques. The recent - and now seemingly indispensable - addition of CT to PET scanners is covered by discussions of theory, image registration and attenuation correction. At only £65 this book is a bargain. My only criticism of the book then is the sense of frustration it arouses by not having the equipment available to start exploiting it. [RAD Magazine, February, 2006]

According to the authors, the purpose is to provide a comprehensive "science of PET" textbook which is more focused and manageable than the original. The authors' intent is "to illustrate the power of clinical PET in substantially altering patient management, thereby avoiding futile aggressive therapy and improving cost effectiveness." The purpose and intent are very laudable, because PET is rapidly gaining momentum in the clinical arena. The book meets the authors' objectives in a superb manner. This book is a must read for physicists, chemists, physicians, and advanced technologists involved or interested in PET. It is the definitive reference in the field at the time of publication. (William R. Hendee, Doody Enterprises, Inc. - COPYRIGHT 2006)

"Positron Emission Tomography: Basic Sciences is a well written book … . This book provides a detailed discussion of the fusion process and the role of CT for anatomical localisation and attenuation correction … . What makes this book important and informative to any reader is that it is a collection of chapters written by luminaries in the field of PET. … We would recommend it to any scientists and clinicians with an interest in medical imaging." (Seu Som and Peter Lim,CancerForum, Vol. 30 (3), November, 2006)

"Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. … The technologist, the science engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will faind (sic) this book invaluable." (Rivista di Neuroradiologia, Vol. 18 (2), 2005)

From the Publisher

5 Stars! from Doody

Reviewer: William R. Hendee, PhD (Medical College of Wisconsin)
Description: This is an updated revision of a 900-page book entitled Positron Emission Tomography: Basic Science and Clinical Practice published in 2003. For this revision, the nonclinical chapters of the original version have been updated, and several chapters have been added to address the science and role of PET in clinical medicine today and in the near future.
Purpose: According to the authors, the purpose is to provide a comprehensive "science of PET" textbook which is more focused and manageable than the original. The authors' intent is "to illustrate the power of clinical PET in substantially altering patient management, thereby avoiding futile aggressive therapy and improving cost effectiveness." The purpose and intent are very laudable, because PET is rapidly gaining momentum in the clinical arena. The book meets the authors' objectives in a superb manner.
Audience: The intended audience for this book includes scientists, engineers, physicians, and medical and graduate students who want to learn more about PET. I agree with the authors that PET "is set to change the whole impact and role of Nuclear Medicine." This book offers those working or interested in nuclear medicine with a "one-stop" introduction to the basic science underlying PET, together with its current and potential clinical applications. The book is multiauthored, with well-known and highly respected editors. All are credible authorities in the field.
Features: This book covers the physics, engineering, and engineering principles of PET, as well as the fundamentals of using PET to image both structure and function and to produce co-registered images. It addresses the production and chemistry of various PET imaging agents, and discusses the role of PET in oncology, drug discovery, molecular imaging and gene expression. The book contains mathematical formulations appropriate to such topics as image reconstruction, quantitative techniques, spatial correspondence of images, and compartmental modeling. The illustrations, some of which are in color, are superb.
Assessment: This book is a must read for physicists, chemists, physicians, and advanced technologists involved or interested in PET. It is the definitive reference in the field at the time of publication. In comparing the book to its previous version published in 2003, I was struck by how much has changed in such a short time. This observation means, of course, that the authors should already be planning the next edition, as the field of PET imaging is expanding and moving very quickly.

Doody's Review Service