Practical Algorithms in Pediatric Hematology and Oncology

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This is the only comprehensive collection of algorithms which exclusively addresses hematologic and oncologic problems affecting neonates, children and adolescents. Examining clinical problems which challenge the pediatrician, general practitioner and family practice physician, each algorithm utilizes a concise, step-by-step approach based upon clues from the history, physical examination and laboratory studies. The algorithms addressing differential diagnosis clearly distinguish between the most common etiologies, those that are less frequent, and finally some that are rare but important to recognize. The 51 topics include evaluation of anemia, sickle cell anemia, thalassemia, hemolytic anemia, the bleeding child, thrombocytopenia and other platelet disorders, hemophilia, leukocyte disorders, leukemias, lymphadenopathy, splenomegaly, approaches to mass lesions in the mediastinum, abdomen, pelvis, bones and soft tissues as well as approaches to potential emergencies such as tumor lysis and superior vena cava syndromes. The oncology topics emphasize diagnostic approach and management of complications, and not the details of chemotherapy. All algorithms are presented with a page of explanatory notes and a list of selected reading. Pediatricians, family physicians and general practitioners will find this book very helpful in managing problems in their practices. Trainees in pediatric hematology will find it a useful tool in developing approaches to solve the problems they will encounter, and pediatric hematologists/oncologists will find it useful as a teaching tool.

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Product Details

  • ISBN-13: 9783805574327
  • Publisher: Karger, S. Inc.
  • Publication date: 2/1/2003
  • Series: Practical Algorithms in Pediatrics Series
  • Edition description: SPIRAL
  • Pages: 114
  • Sales rank: 1,287,804
  • Product dimensions: 10.90 (w) x 8.30 (h) x 0.20 (d)

Table of Contents

Contributors 1
Preface 2
Introduction 3
Red Cells Disorders
Initial evaluation of anemia 4
Microcytic anemia 6
Normocytic anemia 8
Macrocytic anemia 10
Pancytopenia 12
Anemia in the neonate 14
Neonatal anemia due to impaired RBC production 16
Hemolytic anemia 18
Hemoglobinuria 20
Presumed iron deficiency anemia which fails to respond to oral iron 22
Thalassemia 24
Newborn screening for hemoglobinopathies 26
Sickle cell anemia with fever 28
Management of painful vaso-occlusive episodes in sickle cell disease 30
Evaluation and management of anemia in sickle cell disease 32
Polycythemia (erythrocytosis) 34
Red cell transfusion 36
White Cell Disorders
Leukocytosis 38
Eosinophilia 40
Neutropenia 42
The child with recurrent infection: leukocyte dysfunction 44
Reticuloendothelial Disorders
Lymphadenopathy: 1. Generalized lymphadenopathy 46
Lymphadenopathy: 2. Localized adenopathy 48
Splenomegaly 50
Coagulation Disorders
Evaluation of a child with bleeding or abnormal coagulation screening tests 52
Evaluation of a child with thrombocytopenia 54
Thrombocytopenia in the well neonate 56
Thrombocytopenia in the ill neonate 58
Platelet dysfunction 60
Thrombocytosis 62
Treatment of bleeding in children with hemophilia 64
Evaluation of a child with hemophilia who fails infusion therapy 66
Consumptive coagulopathy 68
Thrombophilia evaluation in a newborn infant with thrombosis 70
Thrombophilia evaluation in a child with thrombosis 72
Malignant Disorders
Assessment of a child with suspected leukemia 74
Assessment of a mediastinal mass 76
Assessment of an abdominal mass 78
Assessment of a pelvic mass 80
Assessment of a soft tissue mass 82
Assessment of bone lesions 84
Initial management of a child with a newly diagnosed brain tumor 86
Supratentorial brain tumors 88
Brain tumors of the posterior fossa, brain stem and visual pathway 90
Initial management of a child with a tumor involving or near the spinal cord 92
Recognition and management of tumor lysis syndrome 94
Recognition and management of superior vena cava syndrome 96
Febrile neutropenia 98
Management of biopsy tissue in children with possible malignancies 100
Diagnosis and management of pulmonary infiltrates during chemotherapy 102
Monitoring for late effects in children with malignancies 104
Useful normal laboratory values 106
Index of Signs and Symptoms 108
Abbreviations 113
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