Practical Differential Diagnosis in Surgical Neuropathology / Edition 1

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Overview

This well-organized guide to many of the more commonly encountered diagnostic problems in surgical neuropathology will serve as a day-to-day guide in most active pathology laboratories. The book focuses on the differential diagnosis of the most common neuropathologic entities encountered by general surgical pathologists. The authors go to great lengths to help readers with important diagnoses on very small amounts of tissue, or decide difficult situations where everything looks the same, or cope with intraoperative consultations when time is short and sample preparations are less than ideal. Richly detailed, Practical Differential Diagnosis in Surgical Neuropathology offers both general and specialist neuropathologists a user-friendly, decision-oriented guide to the major diagnostic problems in surgical neuropathology, one that will greatly facilitate successful day-to-day neuropathologic diagnosis, and thus the optimal care of patients.

The book contains black-and-white illustrations.

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Editorial Reviews

Joe Ma
This book is a description of the diagnostic challenges (neoplastic and non-neoplastic) of surgical neuropathology. Both authors are very experienced in the field and they have, for the most part, succeeded in the inclusion of the most practical information needed for diagnostic consideration. The text is surprisingly easy to read despite a few obvious typographic errors, and any surgical pathologist would enjoy the natural flow of information given. Radiologists and neurosurgeons, however, may find the indispensable morphologic details difficult to follow. The authors begin with a brief introduction to intraoperative consultation, followed by 34 concise chapters of different diseases, each replete with pathology, immunohistochemistry, genetics, clinical history, radiology, differential diagnoses, treatment of choice, and prognostic implications. Most are conveniently summarized in tables. They cover almost all neoplasms in the neuraxis and several important inflammatory diseases. In addition to the popular grading systems of diffuse fibrillary astrocytomas, specific variants of astrocytomas are delineated. The responsiveness to chemotherapy of oligodendrogliomas (well differentiated or anaplastic) and mixed oligoastrocytomas is emphasized. Important mimics of neoplasm, such as multiple sclerosis and radiation necrosis, are discussed separately. Pertinent immunohistochemical findings and caveats (such as immunoreactivity of astrocytic cytoplasm to antibodies against pancytokeratins) are included whenever applicable. All the key features are displayed in photomicrographs, although pathologists and non-pathologists alike may find the black-and-white illustrations less impressivethan colored ones. The references in each and every chapter are relevant and quite up-to-date, but this approach results in a few duplicate appearances and possible waste of space. Compared with three other references in surgical neuropathology of similar size: Burger's Tumors of the Central Nervous System (AFIP); Kleihues' Pathology and Genetics: Tumors of the Nervous System (International Agency for Research on Cancer, 1997); and Moss' Intra-Operative Diagnosis of CNS Tumors (Arnold, 1997), this monograph contains very practical information, is very easy to read and comprehend, and is convenient to use in daily intraoperative consultation and regular sign-out.
Booknews
Prayson (anatomic pathology, Cleveland Clinic Foundation) and Cohen (pathology, Case Western Reserve U.) present a guide to the more commonly encountered diagnostic problems in surgical neuropathology. They focus on the differential diagnosis of the most common neuropathological entities encountered by general surgical pathologists. Information is provided on how to work with very small amounts of tissues, decide difficult situations where everything looks the same, and cope with inoperative calculations when time is short and sample preparations are less than ideal. Annotation c. Book News, Inc., Portland, OR (booknews.com)
From The Critics
Reviewer: M. Joe Ma, M.D., Ph.D.(Associated Pathologists, Chartered)
Description: This book is a description of the diagnostic challenges (neoplastic and non-neoplastic) of surgical neuropathology.
Purpose: Both authors are very experienced in the field and they have, for the most part, succeeded in the inclusion of the most practical information needed for diagnostic consideration.
Audience: The text is surprisingly easy to read despite a few obvious typographic errors, and any surgical pathologist would enjoy the natural flow of information given. Radiologists and neurosurgeons, however, may find the indispensable morphologic details difficult to follow.
Features: The authors begin with a brief introduction to intraoperative consultation, followed by 34 concise chapters of different diseases, each replete with pathology, immunohistochemistry, genetics, clinical history, radiology, differential diagnoses, treatment of choice, and prognostic implications. Most are conveniently summarized in tables. They cover almost all neoplasms in the neuraxis and several important inflammatory diseases. In addition to the popular grading systems of diffuse fibrillary astrocytomas, specific variants of astrocytomas are delineated. The responsiveness to chemotherapy of oligodendrogliomas (well differentiated or anaplastic) and mixed oligoastrocytomas is emphasized. Important mimics of neoplasm, such as multiple sclerosis and radiation necrosis, are discussed separately. Pertinent immunohistochemical findings and caveats (such as immunoreactivity of astrocytic cytoplasm to antibodies against pancytokeratins) are included whenever applicable. All the key features are displayed in photomicrographs, although pathologists and non-pathologists alike may find the black-and-white illustrations less impressive than colored ones. The references in each and every chapter are relevant and quite up-to-date, but this approach results in a few duplicate appearances and possible waste of space.
Assessment: Compared with three other references in surgical neuropathology of similar size: Burger's Tumors of the Central Nervous System (AFIP); Kleihues' Pathology and Genetics: Tumors of the Nervous System (International Agency for Research on Cancer, 1997); and Moss' Intra-Operative Diagnosis of CNS Tumors (Arnold, 1997), this monograph contains very practical information, is very easy to read and comprehend, and is convenient to use in daily intraoperative consultation and regular sign-out.

3 Stars from Doody
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Product Details

  • ISBN-13: 9781617372018
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 11/5/2010
  • Edition description: Softcover reprint of hardcover 1st ed. 2000
  • Edition number: 1
  • Pages: 179
  • Product dimensions: 8.25 (w) x 11.00 (h) x 0.41 (d)

Table of Contents

Intraoperative Consultation. Gliosis. Fibrillary Astrocytoma. Low-Grade Astrocytoma Variants. High-Grade Astrocytoma Variants. Radiation Change. Pilocytic Astrocytoma. Pleomorphic Xanthoastrocytoma. Subependymal Giant Cell Astrocytoma. Oligodendroglioma. Mixed Gliomas. Ependymoma. Subependymoma. Myxopapillary Ependymoma. Central Neurocytoma. Dysembryoplastic Neuroepithelial Tumor. Ganglioma and Ganglion Cell Tumors. Choroid Plexus Tumors. Meningioma. Meningeal Sarcoma. Hemangioblastoma. Central Nervous System Primitive Neuroectodermal Tumors. Pineal Region Tumors. Pituitary Gland Lesions. Primary Central Nervous System Lymphoma. Schwannoma. Benign Epithelial Lesions-Craniopharyngiomas and Cysts. Melanocytic Lesions. Paraganglioma. Chordoma. Tumor-Like Demyelinating Lesion. Vascular Malformations. Central Nervous System Vasculitis. Granulomatous Inflammation. Meningitis, Abscess, and Encephalitis. Index.
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