Practical Immunopathology of the Skin

by Bruce R. Smoller

Overview

Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and their multiple diagnostic uses in actual clinical case studies. The author presents in an easily digestible form a dictionary of antibody probes, summarizing for each antibody the targeted antigen and its cellular function, its diagnostic utility, and, when available, its sensitivities and specificities for identifying various neoplasms. Real clinical cases from the author's practice demonstrate the benefits of immunopathology.

Product Details

ISBN-13:	9781588291493
Publisher:	Springer-Verlag New York, LLC
Publication date:	08/23/2002
Series:	Current Clinical Pathology
Edition description:	2002
Pages:	198
Product dimensions:	5.98(w) x 9.02(h) x 0.03(d)

Table of Contents

I. Introduction.- 1 Overview.- 2 Immunoperoxidase: The Technique.- II. Antibody Directory.- 3 Epithelial Markers.- 4 Mesenchymal Markers (Nonhematopoietic).- 5 Hematopoietic Markers.- 6 Melanocyte Markers.- 7 Neuroectodermal (Other than Melanocytic) and Neuroendocrine Markers.- 8 Antibodies Used to Identify Infectious Diseases.- 9 Markers Useful in Detecting Metastatic Disease.- III. Vignettes.- 10 Vignettes.

Editorial Reviews

Referring readers to other sources for the theoretical aspects of immunopathology, Smoller (pathology and dermatology, U. of Arkansas for Medical Sciences-Little Rock) offers laboratory technicians a practical user's manual. He briefly reviews the science behind immunopathology, the immunoperoxidase technique and its most frequently used modifications, tissue preparation, antigen retrieval, and laboratory pitfalls. Then he profiles seven common antibody probes, arranged by the types of cells they help characterize. To conclude, he presents a number of vignettes taken from his own practice. The illustrations are monochromatic. Annotation c. Book News, Inc., Portland, OR

"This book contains the best discussion on the subject and I would recommend it as a requirement for dermatologists and pathologists. This field has become more and more technical and understanding this subject is a necessity for anyone dealing with skin pathology" - Doody's Health Sciences Book Review Journal

"The book fulfills its stated aim of providing dermatologists, in training or active practice, with a working repertoire of useful antibodies. Those reporting dermatopathology from a general histopathology background will come across few surprises, but will still find it valuable to savor and learn from an international expert in dermatopathology." - ACP News

"Residents in dermatology and pathology, clinicians, and practicing pathologists and dermatopathologists all will find this book valuable and highly instructive." - SkinMed

From the Publisher