Practical Lipid Management / Edition 1

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $29.64
Usually ships in 1-2 business days
(Save 67%)
Other sellers (Hardcover)
  • All (11) from $29.64   
  • New (6) from $64.58   
  • Used (5) from $29.64   


Practical Lipid Management: Concepts and Controversies presents a user-friendly overview of lipid management and a concise summary of best practice according to various international guidelines. Featuring a summary of the various international guidelines and highlights areas of consensus, the book provides balanced guidance on issues about which expert opinion is divided or rapidly evolving. It helps the busy clinician to focus on the key aspects of lipid management for the evaluation and treatment of lipid disorders. Practical Lipid Management: Concepts and Controversies forms an invaluable and useful tool for all primary care physicians and others involved in the management of dyslpidaemias and diseases such as diabetes and atherothrombosis.

Read More Show Less

Editorial Reviews

Doody's Review Service
Reviewer: Christopher Lee Allen, MD (University of Kentucky College of Medicine)
Description: In this thorough overview of lipid disorders and management, the authors present evidence-based guidelines for the practical management of patients with lipid disorders.
Purpose: The authors sought to provide a concise, user-friendly overview of the lipid management process, including areas of uncertainty and evolution. The authors do an outstanding job in meeting their objective.
Audience: The book is written for primary care clinicians, which the authors suggest include physicians, advanced practice nurses, and physician assistants, as well as clinicians in training, pharmacists, and dietitians. Given the complexity of this topic, and the detail the book provides, this may be an ambitious audience.
Features: The authors have provided an excellent resource for lipid management. They are able to provide sufficient epidemiological background and information on basic science, clinical management, and emerging strategies. The figures denoted as plates 1-9 are high quality and very useful. I would like to see a more concise summary of clinical recommendations.
Assessment: This is an essential book for physicians (both primary care and subspecialist) who manage patients with lipid disorders. There is no comparable book that provides the depth of information this one does while remaining practical in approach. As new therapies evolve, and additional clinical trials are published, an updated edition will be required. However, this version provides an excellent foundation for the understanding and management of lipid disorders.
From the Publisher
"This is an essential book for physicians who manage patients with lipid disorders. There is no comparable book that provides the depth of information this one does while remaining practical in approach." (Doody's, September 2009)
Read More Show Less

Product Details

  • ISBN-13: 9780470056905
  • Publisher: Wiley
  • Publication date: 12/10/2008
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 256
  • Product dimensions: 5.30 (w) x 7.80 (h) x 0.80 (d)

Table of Contents




Chapter 1 Epidemiology of Lipids, Lipid Management and Risk for Coronary Heart Disease: An Overview.

1.1 Early History of Cardiovascular Epidemiology.

1.2 Lipid Risk Factors are Central to Efforts at CHD Prevention.

1.3 LDL-C and CHD Risk.

1.4 LDL-C Lowering and CHD Risk Reduction.

1.5 Other Atherogenic Lipoproteins: Atherogenic Remnants.

1.6 HDL-C and CHD Risk.

1.7 Trends in Lipids and Lipid Management in the USA.

1.8 The National Cholesterol Education Program Evaluation Project Using Novel E-Technology (NEPTUNE) II Survey.

Controversy: Should a Measure of Atherogenic Lipoprotein Particle Number be used in Risk Assessment And/Or to Evaluate the Response to Lipid Therapy?

Chapter 2 Vascular Biology and Atherogenesis.

2.1 Introduction.

2.2 Arterial Structure.

2.3 Endothelial Cell Function and Dysfunction.

2.4 The Role of Monocytes and Lymphocytes.

2.5 Atheromatous Plaques.

Chapter 3 Detection, Evaluation, and Treatment Goals for Lipid Disorders in Adults.

3.1 Matching Aggressiveness of Treatment to Absolute Risk.

3.2 Screening for Dyslipidemias.

3.3 Risk Stratification.

3.4 Steps in the Risk Stratification Process – Major Risk Categories.

3.5 Tips for Calculating the Framingham Risk Score.

3.6 Subcategories for Consideration ofMore Aggressive Optional Treatment Goals.

3.7 Very High Risk Patients, Optional LDL-C Goal <70 mg dl−1 40.

3.8 Moderately High Risk Patients, OPTIONAL LDL-C Goal <100 mg dl−1 40.

3.9 Treatment Goals for Patients with Elevated Triglycerides.

3.10 Triglycerides and HDL-C as Targets for Therapy.

Controversy: Should Treatment Guidelines Include Targets for the Total/HDL Cholesterol Ratio?

Chapter 4 Therapeutic Lifestyle Changes in the Management of Lipid Disorders and the Metabolic Syndrome.

4.1 Nature and Nurture in the Development of CHD Risk Factors.

4.2 Lifestyle Factors as Determinants of CHD Risk in Populations.

4.3 Within Country Variations in Lifestyle and CHD Risk.

4.4 The Metabolic Syndrome.

4.5 Therapeutic Lifestyle Changes.

4.6 The TLC Diet.

4.7 Dietary Adjuncts: Viscous Fibers and Plant Sterol/Stanol Products.

4.8 Physical Activity and Weight Reduction.

4.9 Smoking Cessation.

4.10 Importance of Allied Health Professionals.

Chapter 5 Management of Elevated Low-Density Lipoprotein Cholesterol.

5.1 Relationship between LDL-C and Risk for Cardiovascular Events.

5.2 Clinical Trial Support for Very Aggressive LDL-C Reduction for Those at Highest Risk.

5.3 Genetic Disorders Associated with Elevated LDL-C.

5.4 Atherogenic Impact of LDL-C.

5.5 Management of Elevated LDL-C.

Controversy: How Low Should We Go?

Controversy: Risks and Benefits of High-Dose Statin Therapy Versus Combination Lipid Drug Therapy.

Controversy: Do the Benefits of Low-Density Lipoprotein Cholesterol Reduction Depend Strictly on “How Low You Go” or also on “How You Get There”?

Chapter 6 Management of Elevated Triglycerides and Non-High-Density Lipoprotein Cholesterol.

6.1 Clinical Factors Associated with Elevated TG and Non- HDL-C Levels.

6.2 Disorders of TG-Rich Lipoprotein Clearance.

6.3 Insulin Resistance and Hypertriglyceridemia.

6.4 Excessive Production of VLDL: The Primary Lipid Abnormality in the Insulin-Resistant State.

6.5 Reasons for Elevated Free Fatty Acid Levels in Insulin- Resistant States.

6.6 Body Fat Distribution and Insulin Resistance.

6.7 Insulin Resistance in the Nonobese Patient.

6.8 Hypertriglyceridemia and the Development of Atherogenic Dyslipidemia.

6.9 Lifestyle Management for the Metabolic Syndrome and Atherogenic Dyslipidemia.

6.10 Drug Therapies.

6.11 Intensification of Efforts to Lower LDL-C as a Means of Achieving the Non-HDL-C Goal.

6.12 Targeting Triglyceride-Rich Lipoprotein Reduction as a Means of Achieving Non-HDL-C Goal.

6.13 Fibrates.

6.14 Niacin.

6.15 Omega-3 Fatty Acids.

6.16 Management of Diabetic Dyslipidemia.

Controversy: Do we Need a Triglyceride Treatment Target to Insure a Predominance of Larger, More Buoyant LDLParticles?

Chapter 7 Management of Depressed High-Density Lipoprotein Cholesterol.

7.1 The Relationship between HDL and Risk For CVD.

7.2 Prevalence of Low HDL-C.

7.3 Goals for HDL Treatment.

7.4 Antiatherogenic Effects of HDL.

7.5 HDL and Insulin Resistance.

7.6 Effects of Lifestyle Modification on Serum HDL.

7.7 Pharmacologic Management of Low HDL.

Controversy: Do we Need HDL Treatment Goals?

Chapter 8 Lipid Management in Population Subsets: Women, the Elderly, Ethnic Minorities, Children, and Adolescents.

8.1 Women.

8.2 Lipids in Women.

8.3 Treatment of Dyslipidemia in Women.

8.4 Sex Hormone Therapy, Lipids, and Cardiovascular Risk in Menopausal Women.

8.5 The Elderly.

8.6 Special Considerations for LipidManagement in the Elderly.

8.7 Ethnic Minorities.

8.8 Risk Factor Incidence and Prevalence in Ethnic Minority Groups.

8.9 Children and Adolescents.

Chapter 9 Emerging Risk Factors and Biomarkers of Cardiovascular Disease.

9.1 Role of Inflammation in the Pathogenesis of Atherosclerosis.

9.2 Biomarkers of Cardiovascular Disease.

Chapter 10 A Primer on Clinical Trials and Critical Review of Clinical Trial Reports for the Clinician.

10.1 Design Issues Affecting the Validity and Generalizability of Clinical Trial Results.

10.2 Chance, Bias, and Confounding as Potential Explanations for Trial Results.

10.3 Efficacy versus Effectiveness.

10.4 Useful Questions to ask when Evaluating a Published Clinical Trial Report.

Chapter 11 Case Studies.


Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)