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Doody's Review ServiceReviewer: Nancy Schell, MD (Rush University Medical Center)
Description: This book brings together top investigators to discuss the role of prenatal factors in schizophrenia.
Purpose: The purpose is to consider the wide range of "epi-genetic" elements that may interact with abnormal genes in the development of schizophrenia.
Audience: It is intended for scientists and clinicians interested in schizophrenia and its possible etiologies.
Features: Evidence suggesting the disease may be the result of environmental factors combined with genetic predisposition is examined. The editors persuasively propose that schizophrenia may result from neurodevelopmental processes beginning before birth. The chapters are divided into four main sections, the first presenting overviews of conceptual models of prenatal influences and the remaining three focusing on infectious, nutritional, and immunological exposures. This book is up-to-date and thorough, yet easy to read, with presentation of ideas and data in an easy to understand framework. References are excellent and the contributors are distinguished in this field.
Assessment: This is an extremely useful book for those interested in the latest research on schizophrenia and, in particular, how it may develop. It is highly recommended.