Primary and Stem Cells: Gene Transfer Technologies and Applications

Primary and Stem Cells: Gene Transfer Technologies and Applications

by Uma Lakshmipathy, Bhaskar Thyagarajan
     
 

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This book describes basic cell engineering methods, emphasizing stem cell applications, and use of the genetically modified stem cells in cell therapy and drug discovery. Together, the chapters introduce and offer insights on new techniques for engineering of stem cells and the delivery of transgenes into stem cells via various viral and non-viral systems. The book

Overview

This book describes basic cell engineering methods, emphasizing stem cell applications, and use of the genetically modified stem cells in cell therapy and drug discovery. Together, the chapters introduce and offer insights on new techniques for engineering of stem cells and the delivery of transgenes into stem cells via various viral and non-viral systems. The book offers a guide to the types of manipulations currently available to create genetically engineered stem cells that suit any investigator's purpose, whether it's basic science investigation, creation of disease models and screens, or cells for therapeutic applications.

Editorial Reviews

From the Publisher
“This is an excellent resource on the new techniques for the engineering of stem cells and the delivery of transgenes into stem cells via various viral and nonviral systems. It provides comprehensive information on the concepts of cell engineering principles and their application in primary and stem cells.  Researchers, established stem cell scientists, and graduate students interested in this field will find this book very handy.”  (Doody’s, 17 August 2012)

Doody's Review Service
Reviewer: Omer Iqbal, MD, FACC, FESC (Loyola University Medical Center)
Description: This is an excellent guide to the currently available techniques to create genetically engineered stem cells that could be used to create disease models and screens, or cells for therapeutic applications.
Purpose: The purpose is to bridge the concepts of genetic engineering with primary and stem cells and to provide an understanding of cell engineering principles and outline their applications in primary and stem cells.
Audience: The book is written for researchers entering the field as well as established stem cell scientists looking to expand their areas of research. Graduate students interested in this field also will find this book very useful.
Features: The four parts of the book cover cloning and gene delivery, nonintegrating technologies, integrating technologies, and applications. Each chapter in these parts discusses a new technology and its applications in primary and stem cells. The book is well illustrated with beautiful figures.
Assessment: This is an excellent resource on the new techniques for the engineering of stem cells and the delivery of transgenes into stem cells via various viral and nonviral systems. It provides comprehensive information on the concepts of cell engineering principles and their application in primary and stem cells. Researchers, established stem cell scientists, and graduate students interested in this field will find this book very handy.

Product Details

ISBN-13:
9781118147160
Publisher:
Wiley
Publication date:
10/31/2011
Sold by:
Barnes & Noble
Format:
NOOK Book
Pages:
304
File size:
7 MB

Related Subjects

What People are saying about this

From the Publisher
“This is an excellent resource on the new techniques for the engineering of stem cells and the delivery of transgenes into stem cells via various viral and nonviral systems. It provides comprehensive information on the concepts of cell engineering principles and their application in primary and stem cells. Researchers, established stem cell scientists, and graduate students interested in this field will find this book very handy.” (Doody’s, 17 August 2012)

Meet the Author

UMA LAKSHMIPATHY is a principal investigator at Life Technologies. She has a PhD in life sciences, with academic and industry experience in molecular biology and stem cells. Dr. Lakshmipathy holds four patents and has authored more than forty publications.

BHASKAR THYAGARAJAN is a program manager at Life Technologies. He has a PhD in pharmacology, with expertise in the areas of molecular biology, DNA recombination, gene and cell therapy, and protein purification. He holds one patent and has authored more than twenty publications.

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