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The subject of thermodynamics is rarely found in Nutrition and Exercise Physiology textbooks. Yet this material is fundamental to any serious inquisition concerning energy exchange.
This book provides a fresh approach to the study of energy expenditure by introducing the latest concepts in open system thermodynamics and cellular to whole-body energy exchange. The text traces biological energy exchange, from the molecules in the food we eat to the energy demands of rest, physical exertion and its recovery.
The carefully researched text advances traditional exercise physiology concepts by incorporating contemporary thermodynamic and cellular physiology principles into the context of a ‘working’ metabolism.
This book is written for upper level undergraduate and graduate students, but will also appeal to exercise physiologists, registered dieticians and nutritionists, and applies to cardiac rehabilitation, exercise science and health fitness programs.
Preface 1. Introduction: Thermodynamics, Bioenergetics, Energy Expenditure Part 1. Thermodynamics 2. Within and Without: Systems and Surroundings 2.1. Isolated systems 2.2. Closed systems 2.3. Open systems 2.4. Life is an open system 3. Conservation 4. Matter and Energy 4.1. Matter 4.2. Energy 4.3. Internal energy 4.4. Internal energy exchanges 5. Energy Accountability: Enthalpy (H) 5.1. The chemical reaction system 5.2. Chemical (standard) enthalpy exchanges 5.3. Biochemical (non-standard) enthalpy exchange 6. Energy has bias: Entropy (S) 6.1. 2nd laws of thermodynamics 6.2. Energy distribution 7. The energy exchange gradient: Gibbs energy (G) 7.1. Delta Go 7.2. Energy unification 7.3. Delta Go’: Closed systems under standard conditions 7.4. Delta G: Non-standard conditions Part 2. Bioenergetics 8. Life’s Currency: ATP 8.1. ATP: structure and content 8.2. ATP: energy exchange 8.3. ATP: turnover efficiency 8.4. ATP utilization (demand) 8.5. ATP re-synthesis 9. Metabolism as an Energy Exchange Device 9.1. Metabolic power: force and flow 9.2. Negative entropy (?) 9.3. Dynamics of a metabolic pathway 9.4. Intracellular transport 9.5. Time 9.6. Exergy synopsis 10. Anaerobic Metabolism 10.1. A brief history of anaerobic biochemistry 10.2. The glycolytic gradient 10.3. Glycolytic heat and entropy 10.4. 'High-energy' phosphate buffering 10.5. Anaerobic speed 11. Aerobic Metabolism 11.1. Mihondria 11.2. Krebs cycle: gradient 1 11.3. Electron transport chain: gradient 2 11.4. Proton-motive force: gradient 3 11.5. The creatine phosphate shuttle 11.6. ATP tally Part 3. Energy Expenditure 12. Aerobic Energy Expenditure 12.1. Combustion, respiration and heat 12.2. Thornton’s law: combustion 12.3. Respiration and energy expenditure 12.4. Heat and gas exchange 12.5. Aerobic energy expenditure as heat and entropy 12.6. CO2 and O2: aerobic and anaerobic energy exchange 13. Anaerobic Energy Expenditure 13.1. The oxygen deficit 13.2. Lactate 14. Energy Expenditure at Rest 14.1. Measuring energy expenditure: calorimetry 14.2. The energy expenditure of rest 14.3. Eating and energy expenditure 14.4. Pregnancy and energy expenditure 15. Energy Expenditure of Activity (Work and Exercise) 15.1. Rate vs capacity vs METs 15.2. Muscle 15.3. Work and energy expenditure relationships 15.4. Glycolytic versus respiratory efficiency 16. Total Energy Expenditure for Exercise and Recovery 16.1. Aerobic exercise energy expenditure 16.2. Anaerobic exercise energy expenditure 16.3. Aerobic recovery energy expenditure 16.4. Dismissing the oxygen debt hypothesis 16.5. Total energy expenditure 16.6. Weight loss: low vs high intensity activity
Posted January 27, 2011
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