Principles and Practice of Gynecologic Oncology

Overview

This updated Fourth Edition provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist.

A significant portion of this edition focuses on monoclonal antibodies, vaccines, and gene ...

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Overview

This updated Fourth Edition provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist.

A significant portion of this edition focuses on monoclonal antibodies, vaccines, and gene directed therapies and how they can greatly improve treatment outcomes. A new chapter on end-of-life care is also included. Three distinguished new editors—Richard R. Barakat, MD, Maurie Markman, MD, and Marcus E. Randall, MD—now join the editorial team.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Emily Berry, BA, MD (Northwestern University Feinberg School of Medicine)
Description: This comprehensive and current textbook addresses all relevant areas of gynecologic oncology, from disease sites and multidisciplinary treatment modalities, to cancer biology and special topics in patient care. The fourth edition, an update from the 2000 publication, continues to be aimed at the specialist in cancer care and is authored by leaders in the related fields.
Purpose: The purpose of this book is threefold: first, to present a text with disease-specific chapters written by a multidisciplinary team of authors; second, to provide the most up-to-date information available about gynecologic malignancies; and third, to highlight the increasing use of multimodal therapies when treating gynecologic malignancies. These are worthy objectives for many reasons. Using authors from the fields of gynecologic oncology, medical oncology, radiation oncology, and pathology ensures that the reader is presented with a comprehensive view in the sections dedicated to disease sites. Each of these specialties is crucial to the diagnosis and treatment of gynecologic malignancies and this book effectively and consistently combines all the relative and current information. There is no doubt when reading the book that the most up-to-date information related to diagnosis and, especially, treatment is presented, with references easy to locate in the bibliography. In sections discussing treatment options for various disease sites, the authors review historical data and end with mention of trials still accruing data. Finally, in regards to multimodal therapies in the field of gynecologic oncology, not only does the book have chapters on radiation oncology and chemotherapy in general, it also has chapters highlighting relatively newer treatment modalities such as immunotherapy, anti-angiogenesis agents, and novel radiotherapy techniques.
Audience: According to the three authors, the book is written for specialists in cancer care, including gynecologic and surgical oncologists, medical oncologists, and radiation oncologists. The authors further assert that the book is also designed to be of assistance to residents and fellows in training for a career in cancer care. I find it is most relevant for the gynecologic oncologist at the level of fellow and above. While it certainly could be useful for residents, the chapters covered material to a depth beyond the needs of newcomers to this topic. The authors are without a doubt credible authorities.
Features: This book covers a variety of topics relevant to the field of gynecologic oncology. In addition to the chapters on individual disease sites, it dedicates space to epidemiology of cancer, cancer cell biology, and biostatistics. In addition, topics in perioperative management, surgical principles, radiation oncology and chemotherapeutic agents are highlighted in depth. Finally, topics particular to care of the cancer patient are included, from pain management and treatment side effects to quality of life and end of life issues. What is best about this book is the solid foundation it provides the reader seeking knowledge about not only the basics, but also the more novel topics related to gynecologic oncology. In particular, the chapters related to specific disease sites are extremely comprehensive in both their material and bibliography of referenced sources. A reader should truly regard this book as their main source of information for the disease sites, and use the bibliography to more thoroughly explore current literature, especially literature pertinent to the treatment of the various diseases. Features particularly unique to this book include a section of color plates (photographs etc.) that can be easily accessed while reading through the book. They demonstrate classic examples of surgical anatomy, clinical exam findings, and characteristic radiographic appearances related to the diagnosis and treatment of gynecologic cancers. In addition, a concise and helpful chapter on diagnostic imaging techniques in gynecologic oncology not only explains what each modality is used for, but also gives advice on which imaging modality to use in a variety of clinical scenarios. Also, the chapter on innovative 21st century therapies provides the latest developments in all arenas of novel therapeutics, a topic that is increasingly important in gynecologic oncology. Finally, there is a section on international, national, and grant-making organizations relevant to gynecologic oncology. In terms of shortcomings, the chapters on radiation oncology and breast cancer are almost too comprehensive for the novice on these topics, and the nutrition chapter could use more visual aids to break up the text.
Assessment: This is truly a staple in the library of any gynecologic oncologist. Particularly useful for fellows and faculty in the field of gynecologic oncology, the book will also be useful for specialists in medical and radiation oncology. More than any other comprehensive book specific to gynecologic oncology, this one should be regarded as the authoritative text, most certainly in light of the additions made to this edition.
David A. Fishman
This is a comprehensive and thorough review of gynecologic oncology. The purpose is to provide a current, comprehensive review of the practice of gynecologic oncology, This is an essential book for anyone interested in this field. Any healthcare provider interested in the current practice of gynecologic oncology should read this book. The author is highly qualified. The overall appearance of the book is excellent. The illustrations are appropriate, and the references and the index are adequate. This text should be mandatory for all physicians caring for patients with gynecological malignancies. It represents a comprehensive effort by the leaders in gynecologic oncology.
Booknews
A text for all members of the team treating patients with gynecological cancer. Section I provides the basic science on oncologic practice and discusses the causes and epidemiology of gynecological cancer, essentials of cancer biology, and general biological principles as they relate to therapy. Section II presents basic principles of surgical treatment, including pre- and postoperative care, radiation therapy, and chemotherapeutic treatment. This section also reviews relevant areas of pain management, palliative care, and psychosexual issues. Section III focuses on specific diseases and disease sites and provides an integrated approach to therapy by stage of disease. This second edition contains new chapters on gynecological oncology for the general ob/gyn, cancer in the pregnant patient, and breast cancer. Annotation c. by Book News, Inc., Portland, Or.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780781746892
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 9/13/2004
  • Edition description: Fourth Edition
  • Edition number: 4
  • Pages: 1419
  • Product dimensions: 8.90 (w) x 11.30 (h) x 2.20 (d)

Table of Contents

1 Epidemiology of gynecologic cancers 3
2 Clinical genetics of gynecologic cancer 33
3 The biology of gynecologic cancer 39
4 Tumor angiogenesis and metastasis : biology and clinical experience 73
5 Oncogenes and tumor-suppressor genes 93
6 Immunotherapy of gynecologic malignancies 123
7 Development and identification of tumor markers 157
8 Cancer prevention strategies 179
9 Clinical trials methodology and biostatistics 199
10 Diagnostic imaging techniques in gynecologic oncology 223
11 Perioperative and critical care 269
12 Surgical principles in gynecologic oncology 311
13 Laparoscopic surgery in gynecologic cancer 333
14 Biologic and physical aspects of radiation oncology 375
15 Principles of chemotherapy in gynecologic cancer 461
16 Pharmacology and therapeutics in gynecologic cancer 489
17 Hormones and human malignancies 561
18 Innovative twenty-first century therapies 587
19 Pathogenesis and diagonsis of preinvasive lesions of the lower genital tract 627
20 Vulva 665
21 Vagina 707
22 Uterine cervix 743
23 Corpus : epithelial tumors 823
24 Corpus : mesenchymal tumors 873
25 Epithelial ovarian cancer 895
26 Ovarian germ cell tumors 989
27 Ovarian sex cord-stromal tumors 989
28 Carcinoma of the fallopian tube 1035
29 Gestational Trophoblastic diseases 1055
30 Breast cancer 1077
31 Management of infections in gynecologic cancer patients 1173
32 Management of late effects of gynecologic cancer treatment 1193
33 Management of pain 1215
34 Rehabilitation as an integrative model : psychologic and surgical approaches 1241
35 Nutritional support of patients with gynecologic cancers 1263
36 Cancer in the pregnant patient 1279
37 AIDS and women 1313
38 Quality of life issues in gynecologic cancer 1333
39 End of life care 1343
App Source information on international, national, and grant-making organizations on relevance to gynecologic oncology 1361
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