Principles and Practice of Psychopharmacotherapy / Edition 4

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The fully updated Fourth Edition of this comprehensive clinical reference summarizes the latest data on hundreds of drug and device-based therapies and offers practical, evidence-based guidelines and treatment strategies for virtually every psychiatric disorder. Coverage includes the recently FDA-approved use of vagus nerve stimulation for treatment-resistant depression and current clinical guidelines on electroconvulsive therapy and transcranial magnetic stimulation, including indications, dosage, variations in treatment, and administration. Other topics addressed include the risks and benefits of psychopharmacotherapy for the pregnant, child, adolescent, geriatric, and dementia patient, and up-to-the-minute strategies for treating schizophrenia, bipolar disorder, anxiety, sleep disorders, obsessive-compulsive and panic disorders, dementia, and more.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: Written and edited by internationally recognized clinician-researchers, this fourth edition retains, at least for me, the status of the gold standard of psychopharmacology textbooks.
Purpose: This edition "is an attempt to organize" the developments in psychopharmacology since the third edition "by reviewing, synthesizing, and then organizing this material into clinical therapeutic strategies. Indeed the editor and chapter authors have produced a scholarly, up to date, and very practical textbook in treating these complicated disorders."
Audience: The intended audience includes "residents in psychiatry and family practice as well as the general practitioners of these medical specialties; psychiatric nurses, psychologists, and social workers; and other mental health professionals who are involved with patients taking psychotropic medications."
Features: The book covers, in sufficient detail, all the important aspects of psychopharmacological practice, including the general principles of psychopharmacology, pharmacodynamics and pharmacokinetics, assessment of efficacy, the indications and treatment for antipsychotic, antidepressants, electroconvulsive therapy and other device-based therapies, mood stabilizers, antianxiety and sedative agents, geriatric and pediatric psychopharmacology, and other special populations such as substance dependent patients, dementia, and delirium. What I especially like is that the editor "puts his nickel down" and provides the reader with stated conclusions regarding particular treatments based on clinical experience and evidence. Each chapter ends with relevant and timely references. The glossary is focused on pharmacologic terms. The index is quite detailed and helpful. The only suggestion I have is that financial disclosures of the chapter authors and editor should have been included, particularly in this era of the public mistrust of pharmaceutical research findings.
Assessment: This textbook remains an outstanding learning source for any clinician involved in the treatment of patients with mental illness. It should be required reading for all residents in psychiatry residency training programs.
Howard M. Kravitz
The second edition of this textbook on drug therapy for the management of mental disorders follows closely the format and organization of the first edition, published in 1993. The text is written by the same four authors, who have integrated their extensive research and clinical experience to produce a clinically oriented book grounded in literature-based evidence. The authors observe that in the four years since the first edition, the continued rapid development of new psychopharmacotherapies necessitated this update. As in the first edition, their goals were to organize the literature so that the readers could assimilate this mass of information and apply it to developing logical treatment strategies. The authors are credible experts who are adept at meeting their goals. The book is directed toward physicians, both residents and practitioners, primarily in psychiatry and family medicine. Others who may appreciate the content offered by the authors include psychiatric nurses, psychologists, social workers, and other mental health professionals who are involved with patients taking psychotropic medications. I might add that general internists and neurologists also may find this a useful reference text. The layout of this new edition is a strength. The print appears larger, key sentences within paragraphs are bolded more often, and there seems to be more liberal use of bullets to highlight major points. Tables and charts summarize groups of studies in ""box score"" fashion, show dose regimens and side effects, and present other useful facts at a glance. Line figures illustrate pharmacokinetics and relapse rates. For the most part, these tables, charts, and figures enhance thereadability. Except for figure 10.1, the authors did well to replace the awful appearing black-background figures. The authors attempted to diagram therapeutic recommendations as treatment algorithms; this venture was less successful. These roadmaps tend to be a bit too busy and overinclusive to be very informative. This remains a solid textbook on psychopharmacotherapeutics, now expanded by more than 100 pages and modified for DSM-IV. If you are watching your pennies, you may not need to purchase a new edition. The authors have been publishing updates covering the new agents, particularly antidepressants and antipsychotics. If the price is right, these updates might suffice for those who own the first edition. Also, some chapters in the second edition were revised more in form than substance. However, libraries need to be up-to-date and should have the newer edition, which incorporates all that was useful in the first edition. For the intended physician audience, residents and busy practitioners, this is a usable text. In a market that is glutted with psychopharmacology texts, both clinical and laboratory-based, this one may have its niche, which the authors hope to maintain by keeping current.
A guide for residents, practitioners, and nurses in psychiatry and family practice; psychologists; social workers; and other mental health professionals involved with patients taking psychotropic medications. Summarizes the current understanding of the principles and practices of drug therapies integrated into the overall management of the mentally ill. Updated from the 1993 edition to include several new drugs and strategies that are more precisely targeted and cause fewer and milder adverse affects, and the rapid growth in the database that must be consulted and applied to specific cases. Annotation c. by Book News, Inc., Portland, Or.
Conceived and written by four authors, each a professor of psychiatry, and in combination bringing some 100 years of research and clinical experience to the task, this volume provides a clinical logic that incorporates contemporary knowledge about drug therapies into the overall management of the mentally ill. Among its other features, the work is characterized by a comprehensive summarization of the literature (some 2,000 references, most since 1985), and by the development of treatment strategies based on the best scientific data available as well as the authors' combined clinical experience. Annotation c. Book News, Inc., Portland, OR (

5 Stars! from Doody
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Product Details

  • ISBN-13: 9780781760577
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 4/28/2006
  • Edition description: Fourth Edition
  • Edition number: 4
  • Pages: 718
  • Product dimensions: 7.10 (w) x 10.10 (h) x 1.50 (d)

Table of Contents

General Principles

Pharmacodynamics and Pharmacokinetics

Assessment of Drug Efficacy and Relevant Clinical Issues

Indications for Antipsychotics

Treatment with Antipsychotics

Indications for Antidepressants

Treatment with Antidepressants

Treatment with Electroconvulsive Therapy and Other Somatic Therapies

Indications for Mood Stabilizers

Treatment with Mood Stabilizers

Indications for Antianxiety and Sedative-Hypnotic Agents

Treatment with Antianxiety and Sedative-Hypnotic Agents

Assessment and Treatment of Anxiety-Related Disorders

Psychopharmacotherapy in Early Life

Psychopharmacotherapy in Later Life

Psychopharmacotherapy in Special Populations


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