Principles of Cellular, Molecular, and Developmental Neuroscience

Overview

This volume provides an overview of the expanding interface between neuroscience and cellular and developmental biology. It is a suitable textbook for advanced undergraduate, graduate, and medical school integrated neuroscience programs. The focus is on the basic principles, major questions, unsolved problems, and experimental strategies vital to an understanding of the primary literature.

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Paperback (Softcover reprint of the original 1st ed. 1989)
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Overview

This volume provides an overview of the expanding interface between neuroscience and cellular and developmental biology. It is a suitable textbook for advanced undergraduate, graduate, and medical school integrated neuroscience programs. The focus is on the basic principles, major questions, unsolved problems, and experimental strategies vital to an understanding of the primary literature.

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Editorial Reviews

Booknews
Reviews structural features and functional activities of neurons; typology and functional role of glia; cellular processes associated with the synthesis of molecules involved in chemical neurotransmission; histogenesis of the nervous system; and recent advances in specific treatment strategies for preventing or reversing central nervous system injury or disease. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9781461281481
  • Publisher: Springer New York
  • Publication date: 7/31/2012
  • Edition description: Softcover reprint of the original 1st ed. 1989
  • Edition number: 1
  • Pages: 257
  • Product dimensions: 6.14 (w) x 9.21 (h) x 0.57 (d)

Table of Contents

1 Cell Biology of Neurons.- I. Neuronal Cell Structure and Its Relation to Function.- Neurons from a Cellular Perspective.- The Cytology of the Nerve Cell.- Axons.- Dendrites.- Neuronal Form and Its Relationship to Function.- Dendritic Form and Integrative Functions.- Spatiotemporal Summation.- II. Molecular Anatomy of Neurons, Intracellular Transport, and Gene Expression.- Molecular Anatomy of Neurons.- The Neuronal Cytoskeleton.- Axoplasmic Transport and the Distribution of Materials Within Neurons.- Gene Expression in Neurons.- Supplemental Reading.- 2 Cell Biology of Glia.- Glial Cells of the CNS.- Glial Cells of the Peripheral Nervous System (PNS).- Functional Roles of Glial Cells.- Functions of Microglia.- Gene Expression in Glial Cells.- Conclusion.- Supplemental Reading.- 3 Interneuronal Communication I: Neurotransmitters.- Nonpeptide Neurotransmitters.- Neuropeptides.- Cellular Mechanisms of Chemical Neurotransmission.- Delivery of Neurotransmitters or Their Enzymes and Storage Within Terminals.- Release (Stimulus-Coupled Secretion).- Inactivation or Degradation of Neurotransmitters.- Supplemental Reading.- 4 Interneuronal Communication II: Neurotransmitter Receptors and Second Messenger Systems.- Ionophore-Linked Receptors.- GABA and Glycine Receptors.- Receptors for Excitatory Amino Acids.- Second Messenger-Linked Receptors.- Functional Significance of Receptor-Mediated Second Messenger Systems.- Supplemental Reading.- 5 Histogenesis of the Nervous System.- The Formation of the Nervous System.- Proliferation and Migration of Neurons and Glia.- Role of Cell Adhesion Molecules in Neural Histogenesis.- Programmed Cell Death in the Nervous System.- Supplemental Reading.- 6 The Formation of Neural Connections I: Axon Growth and Guidance.- Elaboration of Axons and-Dendrites.- Axonal Overproliferation and Withdrawal.- Supplemental Reading.- 7 The Formation of Neural Connections II: Dendritic Development and the Establishment of Synaptic Connections.- The Development of Dendrites.- Specificity in the Formation of Topographically Ordered Projections.- Rearrangement of Synaptic Connections During Development.- Construction of Synaptic Connections.- Transsynaptic Regulation of Neuronal Differentiation.- Supplemental Reading.- 8 Nervous System Regeneration and Repair Following Injury.- Regressive Phenomena Following Injury.- Adaptive Changes in Response to Trauma.- Reactive Growth of Axons and Synapses.- Transplants and Grafts.- Supplemental Reading.

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