Principles of Development / Edition 4

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Overview


Developmental biology is at the core of all biology. It deals with the processes by which the genes in the fertilized egg control cell behavior in the embryo and so determine its pattern, its form, and much of its behavior. The progress in developmental biology in recent years, with the applications of advances in cell and molecular biology, has been remarkable, and an enormous amount of information is now available.
Designed for undergraduates, Principles of Development emphasizes basic principles and key concepts in developmental biology. Central to the authors' approach is the idea that development can best be understood by analyzing how genes control cell behavior. They have assumed that students have some basic familiarity with cell biology and genetics, but all key concepts, like the control of gene activity, are explained in the text. The authors have resisted the temptation to cover every aspect of development and have instead focused on those systems that best illuminate common principles, demonstrating throughout the book that there are universal principles governing development. The focus of the text is on vertebrates and Drosophila, but not to the exclusion of other systems, such as the nematode and the sea urchin, where they best illustrate a concept. An important feature of the book is the inclusion of the development of plants, a topic that has some unique and significant attributes but one that is usually neglected in other texts. Principles are presented clearly and numerous summaries are provided, both in words and in pictures. The illustrations in the book have been carefully designed and chosen to illustrate both experiments and mechanisms.
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Editorial Reviews

From the Publisher
"This new edition is a significant and positive step in presenting a complex field of study to undergraduate students."—Craig M. Scott, Clarion University

"I like the boxes in each chapter. Experimental technique boxes work well when the reader just wants to look up a technique. Boxes are also a good way to highlight concepts, or to go into detail on subjects that may or may not be covered in lectures."—Deborah Garrity, Colorado State University

"Very clear writing style that the students will appreciate, and very clear figures."—Margaret Saha, College of William and Mary

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Product Details

  • ISBN-13: 9780199554287
  • Publisher: Oxford University Press, USA
  • Publication date: 12/1/2010
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 720
  • Sales rank: 229,640
  • Product dimensions: 8.20 (w) x 10.60 (h) x 1.00 (d)

Meet the Author

Lewis Wolpert, Department of Biochemistry and Molecular Biology, University College London

Jim Smith, Cancer Research UK Gurdon Institute, Cambridge

Tom Jessell, Department of Biochemistry and Molecular Biophysics, University of Columbia, New York Peter Lawrence, MRC Laboratory of Molecular Biology, Cambridge Elizabeth Robertson, The Wellcome Trust Centre for Human Genetics, Oxford

Elliot Meyerowitz, California Institute of Technology

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Table of Contents

Ch. 1 History and basic concepts 1
Ch. 2 Development of the Drosophila body plan 31
Ch. 3 Patterning the vertebrate body plan I : axes and germ layers 89
Ch. 4 Patterning the vertebrate body plan II : the somites and early nervous system 149
Ch. 5 Development of nematodes, sea urchins, ascidians, and slime molds 185
Ch. 6 Plant development 225
Ch. 7 Morphogenesis : change in form in the early embryo 257
Ch. 8 Cell differentiation and stem cells 297
Ch. 9 Organogenesis 339
Ch. 10 Development of the nervous system 387
Ch. 11 Germ cells, fertilization, and sex 421
Ch. 12 Growth and post-embryonic development 451
Ch. 13 Regeneration 475
Ch. 14 Evolution and development 497
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